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Electron extraction from excited quantum dots with higher order coulomb scattering
The electron kinetics in nanowire-based hot-carrier solar cells is studied, where both relaxation and extraction are considered concurrently. Our kinetics is formulated in the many-particle basis of the interacting system. Detailed comparison with simplified calculations based on product states shows that this includes the Coulomb interaction both in lowest and higher orders. While relaxation rate
Humoral first-line mucosal innate defence in vivo
Based on observations in vivo in guinea-pig and human airways, this review presents plasma exudation as non-sieved transmission of bulk plasma across an unperturbed mucosa that maintains its normal barrier functions. Several steps have led to the present understanding of plasma exudation as a non-injurious response to mucosal challenges. The implication of a swift appearance of all circulating mul
Äktenskap i Theorin : en lundensisk kärleksskandal från 1878
En lundensisk stadsläkare, en dansk diktare, och en pappersfabrikants dotter bor under samma tak – det skulle kunna vara inledningen på ett dålig vits, men är i själva verket början på ett kärleks- och triangeldrama som skakade Lund under andra halvan av artonhundratalet. Arkivarien vid universitetsarkivet Henrik Ullstad skriver om en äktenskapsskandal som slog sönder familjer, krossade en lovandeA town medical officer in Lund, a Danish poet and a paper manufacturer’s daughter living under the same roof – it could be the start to a bad joke, however, it is actually the start of a dramatic love triangle that shook Lund during the second half of the nineteenth century. University archivist Henrik Ullstad writes about a relationship scandal that destroyed families, crushed a promising career,
Quantitative, qualitative and spatial analysis of lymphocyte infiltration in periampullary and pancreatic adenocarcinoma
Immunotherapeutic modalities are currently revolutionizing cancer treatment. In pancreatic cancer, however, early clinical trials have been disappointing. The optimization of immunotherapeutic strategies requires better understanding of the inflammatory tumor microenvironment. Therefore, the aim of our study was to perform a detailed in situ description of lymphocyte infiltration patterns in resec
‘We are rich in mass graves’ : representing a history of violence through Êzîdî poetry
The 2014 Êzîdî Genocide caused a rupture in the social fabric of the Iraqi religious Êzîdî minority. A search for meaning in the aftermath of violence has caused a group of Şingalî poets to reconstruct memories of the past through their narration in Arabic prose poetry. A narrative analysis has been used on a selection of poems written and interviews conducted with five poets. I investigate their
Smartphones and Newton's first law in escalators and roller coasters
Your body is not a point particle. The nature and direction of the forces counteracting gravity influence your experience of uniform rectilinear motion- A s does your own orientation in relation to the force of gravity. Sensors in smartphones or other devices can capture these forces, and help establish a connection between the personal experience of motion and the textbook description of forces a
Body surface temperature responses to food restriction in wild and captive great tits
During winter at temperate and high latitudes, the low ambient temperatures, limited food supplies and short foraging periods mean small passerines show behavioural, morphological and physiological adaptations to reduce the risk of facing energy shortages. Peripheral tissues vasoconstrict in low ambient temperatures to reduce heat loss and cold injury. Peripheral vasoconstriction has been observed
Experimental facilitation of heat loss affects work rate and innate immune function in a breeding passerine bird
The capacity to get rid of excess heat produced during hard work is a possible constraint on parental effort during reproduction [heat dissipation limit (HDL) theory]. We released hard-working blue tits (Cyanistes caeruleus) from this constraint by experimentally removing ventral plumage. We then assessed whether this changed their reproductive effort (feeding rate and nestling size) and levels ofThe capacity to get rid of excess heat produced during hard work is a possible constraint on parental effort during reproduction [heat dissipation limit (HDL) theory]. We released hard-working blue tits (Cyanistes caeruleus) from this constraint by experimentally removing ventral plumage. We then assessed whether this changed their reproductive effort (feeding rate and nestling size) and levels of
Preface : The evolving scenario of Parkinson's research
Age differences in night-time metabolic rate and body temperature in a small passerine
Spending the winter in northern climes with short days and cold ambient temperatures (Ta) can be energetically challenging for small birds that have high metabolic and heat loss rates. Hence, maintaining body temperature (Tb) in Ta below thermoneutrality can be energetically costly for a small bird. We still know little about how increased heat production below thermoneutrality affects the level aSpending the winter in northern climes with short days and cold ambient temperatures (Ta) can be energetically challenging for small birds that have high metabolic and heat loss rates. Hence, maintaining body temperature (Tb) in Ta below thermoneutrality can be energetically costly for a small bird. We still know little about how increased heat production below thermoneutrality affects the level a
Reduced immune responsiveness contributes to winter energy conservation in an Arctic bird
Animals in seasonal environments must prudently manage energyexpenditure to survive the winter. This may be achieved throughreductions in the allocation of energy for various purposes (e.g.thermoregulation, locomotion, etc.). We studied whether such tradeoffsalso include suppression of the innate immune response, bysubjecting captive male Svalbard ptarmigan (Lagopus mutahyperborea) to bacterial liAnimals in seasonal environments must prudently manage energyexpenditure to survive the winter. This may be achieved throughreductions in the allocation of energy for various purposes (e.g.thermoregulation, locomotion, etc.). We studied whether such tradeoffsalso include suppression of the innate immune response, bysubjecting captive male Svalbard ptarmigan (Lagopus mutahyperborea) to bacterial li
Proliferation and benevolence—A framework for dissecting the mechanisms of microbial virulence and health promotion
Key topics in the study of host–microbe interactions—such as the prevention of drug resistance and the exploitation of beneficial effects of bacteria—would benefit from concerted efforts with both mechanistic and evolutionary approaches. But due to differences in intellectual traditions, insights gained in one field rarely benefit the other. Here, we develop a conceptual and analytical framework f
Night conditions affect morning incubation behaviour differently across a latitudinal gradient
Intermittently incubating birds alternate between sessions of egg warming and recesses for foraging during the day, but stay on the nest continuously at night. Hence, energy costs of nocturnal incubation (which increase during longer and colder nights) cannot be replenished until the next day. Night conditions might therefore be expected to affect morning incubation behaviour the day after. We tesIntermittently incubating birds alternate between sessions of egg warming and recesses for foraging during the day, but stay on the nest continuously at night. Hence, energy costs of nocturnal incubation (which increase during longer and colder nights) cannot be replenished until the next day. Night conditions might therefore be expected to affect morning incubation behaviour the day after. We tes
Multivariate Analysis of Orthogonal Range Searching and Graph Distances
We show that the eccentricities, diameter, radius, and Wiener index of an undirected n-vertex graph with nonnegative edge lengths can be computed in time O(n·(k+⌈logn⌉k)·2klogn), where k is linear in the treewidth of the graph. For every ϵ> 0 , this bound is n1 + ϵexp O(k) , which matches a hardness result of Abboud et al. (in: Proceedings of the Twenty-Seventh Annual ACM-SIAM Symposium on Discret
A new maximal bicycle test using a prediction algorithm developed from four large COPD studies
Background: Maximum exercise workload (WMAX) is today assessed as the first part of Cardiopulmonary Exercise testing. The WMAX test exposes patients with COPD, often having cardiovascular comorbidity, to risks. Our research project was initiated with the final aim to eliminate the WMAX test and replace this test with a predicted value of WMAX, based on a prediction algorithm of WMAX derived from m
Perceived Barriers to Decision Quality in Three Swedish Public Authorities
Barriers to decision quality were reported by 473 administrative officers and investigators in three Swedish national public authorities: the Tax Agency, Social Insurance Agency, and Police Authority. In line with previous research, we assumed that limited possibilities to plan one’s work would hinder decision quality. Both disruption of workflow and high workload were reported to inhibit work pla
Optimization study on periodic counter-current chromatography integrated in a monoclonal antibody downstream process
An optimization study of an integrated periodic counter-current chromatography (PCC) process in a monoclonal antibody (mAb) downstream process at lab scale, is presented in this paper. The optimization was based on a mechanistic model of the breakthrough curve in the protein-A capture step. Productivity and resin utilization were the objective functions, while yield during the loading of the captu
Phase-field fracture modelling of crack nucleation and propagation in porous rock
In this work, we suggest a modified phase-field model for simulating the evolution of mixed mode fractures and compressive driven fractures in porous artificial rocks and Neapolitan Fine Grained Tuff. The numerical model has been calibrated using experimental observations of rock samples with a single saw cut under uniaxial plane strain compression. For the purpose of validation, results from the
Cellular and molecular mechanisms in immune mediated hepatic fibrosis. A study of the inflammatory syndrome and fibrosis development of the NIF mouse liver.
Fibrosis is the result of dysregulated inflammation and tissue repair, and is characterized by the excessive accumulation of extra cellular matrix (ECM) proteins. It causes detrimental effects to the afflicted tissue and can subsequently lead to organ failure. Sterile liver inflammation and hepatic fibrosis are associated with many liver disorders of different etiologies. Both type 1 and type 2 in
