Formulations for buccal drug delivery often comprise polymers to facilitate mucoadhesion based on water sorption. The main objective of the current study was therefore to evaluate the effect of dehydration on drug uptake through oral mucosa. We have used diffusion cells with excised porcine mucosa to study uptake of three alternative drugs (i.e., Metronidazole, Benzydamine and Xylometazoline) toge

Objectives: Endometriosis has been associated with a wide range of factors. The disease share immunological features with autoimmune diseases, and the prevalence of both hypo- and hyperthyroidism has been reported to be increased. However, the associations have to be confirmed and the mechanisms explored. The aim of this observational study was to investigate socioeconomic factors, lifestyle habit

Food may induce inflammation and favor development of metabolic diseases, which have been associated with increased inflammation and potential risk of cognitive impairment. It is customary to know whether food or disease promote inflammation. Our hypothesis was that Okinawan-based Nordic (O-BN) diet leads to decreased circulating concentrations of inflammatory and neural biomarkers. The objectives

This article explores the intersection between the indiscernible forces of urbanisation and the materialisation of architectural form. Taking the design of architectural concept for an Accessory Dwelling Unit (ADU) at Råå in Sweden as an applied research project, the article argues that new techniques are needed to analyse interactions between artistic intentionality and indiscernible forces, and

This article investigates language use in sports, and more specific how trainers address their young trainees in athletics, jujutsu, and gymnastics. The article focuses the instructions that the trainees receive when performing different exercises during training. The primary theoretical framework is Bernstein’s (1971 and onwards) concepts classification, framing, and a collective as opposed to an

The post accelerator REX-ISOLDE is installed at the ISOLDE facility at CERN, where a broad variety of radioactive ions can be addressed. Since the end of 2001 beams at the final energy of 2.2 MeV/u are available. REX-ISOLDE uses a unique system of beam bunching and charge breeding. First a Penning trap accumulates and bunches the ions, which are delivered as a quasi-continuous beam from the ISOLDE

Denna rapport beskriver ett urval av 1184 vuxna svenskar (medelvärdesålder = 48.72 år, standardavvikelse = 12.17; 75.5 % kvinnor, 1.3 % annan eller ej angiven könsidentitet) som upplever olika typer av fysisk smärta. Data samlades in via en internetenkät, som under 2017 utannonserades via olika patientföreningar, sociala medier och vårdcentraler. I bortsett från att de flesta av deltagarna identifThis report presents the demographics of a community sample of 1184 Swedish adults (mean age = 48.72 years, SD = 12.17; 75.5 % women, 1.3 % other or undisclosed gender identity) who currently experience physical pain of various origins. Data was collected via an internet survey advertised through patient societies, social media, and healthcare clinics during 2017. Although the majority identified

Information on gross [Formula Presented]-decay properties of neutron-rich noble gas isotopes [Formula Presented] was obtained at the PSB-ISOLDE facility at CERN using isobaric selectivity achieved by the combination of a plasma ion source with a cooled transfer line and subsequent mass separation. A doubly charged beam was used in the case of [Formula Presented] to suppress the corresponding multi

A study of the low-lying levels of 128Ba was performed using three clover detectors in a compact arrangement. The levels were populated by beta decay of 128La which was produced by the fusion evaporation reaction 116Sn(16O, 1p3n). γ-γ angular correlations and polarization measurements were performed. The decay properties of several low-lying states were investigated. Spin assignments were made for

The mirror β+ decay of 61Ga was investigated by means of β- and γ-ray spectrometry at the ISOLDE-PSB facility using laser ionization and mass separation. The results for the 61Ga half-life and the QFC value are 168(3) ms and 9255(50) keV, respectively. The β-decay strength to the ground and low-lying excited states of the daughter 61Zn was deduced. The experimental results are in a good agreement