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Apolipoprotein M: Progress in understanding its regulation and metabolic functions

ApoM is a novel apolipoprotein mainly present in high-density lipoprotein (HDL). It belongs to the lipocalin protein superfamily and may bind a small but so far unknown lipophilic ligand. It is secreted without cleavage of its hydrophobic signal peptide, which probably anchors apoM in the phospholipid moiety of plasma lipoproteins. Recent studies suggest that apoM may affect HDL metabolism and hav

Greater reduction of knee than hip pain in osteoarthritis treated with naproxen, as evaluated by WOMAC and SF-36

Objectives: To compare the improvement of hip and knee osteoarthritis during treatment with naproxen. Methods: Men and women aged 40 to 75 years with symptomatic osteoarthritis of the knee or hip of at least three months' duration participated in a six week placebo controlled, double blind study with naproxen 500 mg twice daily as one treatment arm. Naproxen was given to 403 patients (280 knee, 12

The Euro cash changeover process

This article describes and analyzes the Euro cash changeover process. The European Monetary Union, EMU, is a unique event in history, although other monetary unions were formed and existed long before. Still, this giant experiment makes it possible to study changes in the monetary environment from a unique and new position. The article tries to find factors that can help to explain the different p

Industrial development of car disassembly - ergonomics and system performance

Popular Abstract in Swedish Ett nytt EU-direktiv om uttjänta fordon har nyligen antagits. Direktivet kräver att från och med 2006 skall 85% av bilens vikt återvinnas och 95% från och med år 2015. Idag återvinns cirka 80%. Bildemonteringsindustrin har valts som studieobjekt i denna avhandling. De höjda återvinningskraven förväntas leda till att bildemonteringsindustrin genomgår omfattande rationaliA new EU directive on used vehicles has recently been introduced. It demands that for every scrapped car, at least 85% by weight must be recycled by the year 2006 and 95% by 2015. The current level is about 80%. The car disassembly industry was chosen as the study object of this thesis. Due to the increased demands on recycling, the disassembly industry may undergo comprehensive rationalizations a

Wound healing and expression of antimicrobial peptides/polypeptides in human keratinocytes, a consequence of common growth factors

In addition to acting as a physical barrier against microorganisms, the skin produces antimicrobial peptides and proteins. After wounding, growth factors are produced to stimulate the regeneration of tissue. The growth factor response ceases after regeneration of the tissue, when the physical barrier protecting against microbial infections is re-established. We found that the growth factors import

Balance in single-limb stance after surgically treated ankle fractures: a 14-month follow-up

Background: The maintenance of postural control is fundamental for different types of physical activity. This can be measured by having subjects stand on one leg on a force plate. Many studies assessing standing balance have previously been carried out in patients with ankle ligament injuries but not in patients with ankle fractures. The aim of this study was to evaluate whether patients operated

Submaximal-exercise-induced impairment of human muscle to develop and maintain force at low frequencies of electrical stimulation

The aim of this study was to test the hypothesis that low intensity exercise-induced low frequency fatigue is caused by failure of excitation-contraction coupling. Changes in knee extension torque at 5, 10, 15, 20 and 50 Hz electrical stimulation of quadriceps muscle in ten healthy, young, male subjects were recorded during 20-min voluntary exercise followed by 60-min recovery. In seven of the ten

The mechanisms controlling heat and mass transfer on frying of beefburgers. III. Mass transfer evolution during frying

The effects of five different meat raw materials used for making beefburgers on the evolution of mass transfer (total, water and fat losses), patty diameter shrinkage and porosity were studied during frying from the frozen state (-20 degrees C) to a centre temperature of 72 degrees C in a double-sided pan fryer. The normalised water losses increased linearly with increasing average temperature at

Land use effects on soil N, P, C and pH persist over 40-80 years of forest growth on agricultural soils

Previous cultivation may have long-lasting effects on oak forests, e.g., nitrogen (N) and carbon (C) depletion, phosphorus (P) enrichment and lowered soil acidity, which may influence soil processes, wood production and plant diversity. We used a large database on land use to sample 18 sites where oak had been planted 40-80 years ago on continuously forested land and formerly cultivated fields tha

Amplification of photon echo signals by use of a fiber amplifier

The efficiency of photon-echo processes typically lies in the 0.1–1% range. For many photon-echo-based applications suggested in optical storage and all-optical communication the photon-echo output pulses would need to be used as input data to a new photon-echo process. In such cases amplification of the photon-echo output signals would be necessary for an acceptable signal-to-noise ratio to be ob

Are gadolinium-based contrast media really safer than iodinated media for digital subtraction angiography in patients with azotemia?

Gadolinium chelates, intended as intravenous contrast media for magnetic resonance imaging, have been regarded as nonnephrotoxic and recommended to replace iodinated contrast media in patients with azotemia who are undergoing digital subtraction angiography (DSA). High intraarterial doses (up to 220 mmol of gadodiamide) have been used, with a 40% incidence of nephropathy. The authors discourage th

No relation between maternal weight gain and stillbirth

BACKGROUND. To evaluate the relationship between stillbirth in singleton pregnancy (> or = 28 weeks gestation) and maternal weight (weight gain) from 24 completed weeks. METHODS. All fetal deaths (n = 210) at five delivery units during seven years in southern Sweden were analysed. To each case a control mother was selected, the only matching criteria being parity and place of delivery. Regression

Analysis of the hypoxia-induced ADH2-promoter of the respiratory yeast Pichia stipitis reveals a new mechanism for sensing of oxygen limitation in yeast

We introduced a reporter gene system into Pichia stipitis using the gene for the artificial green fluorescent protein (GFP), variant yEGFP. This system was used to analyse hypoxia-dependent PsADH2 regulation. Reporter gene activity was only found under oxygen limitation on a fermentable carbon source. The promoter was not induced by oxygen limitation in the Crabtree-positive yeast Saccharomyces ce

New species of Xanthoria (Teloschistaceae) from Australia

New species of Xanthoria (Teloschistaceae) from Australia. Nuytsia 16(1) 63–76(2006). Xanthoria elixii S. Kondr. & Kärnefelt, sp. nov. and X. streimannii S. Kondr. & Kärnefelt, sp. nov. are described, illustrated and compared with allied taxa, and a detailed description of the common and widespread species X. filsonii Elix is also given. A key to Australian taxa of Xanthoria is provided.

Sexual child abuse in a defined Swedish area 1993-97: a population-based survey

Attempting to avoid some of the most common methodological problems involved in research on sexual child abuse, we collected data on crimes, perpetrators, and sanctions in all convicted cases of sexual child abuse in a defined population during a 5-year period. This approach provided amply documented and ascertained cases with precise definitions and descriptions of the crimes involved, no clinica

Soil solution electrical conductivity measurements using different dielectric techniques

Accurate measurements of soil solution electrical conductivity (or.) are needed in various applications. One recently developed technique that measures sigma(w) is the Sigma Probe (SP). The SP is supposed to give accurate readings only-slightly dependent on water content (theta) and soil type. To test the performance of the SP, it was compared with another dielectric technique, time domain reflect

Age, parasites, and condition affect humoral immune response in tropical pythons

Mounting an immune response has been suggested to be physiologically costly because of metabolic requirements of immune cells specifically and upregulation of the immune system in general. We investigated such costs in free-living water pythons (Liasis fuscus), immunized with a harmless antigen, keyhole limpet hemocyanin. In the present study, we analyze the independent effects of age, blood paras