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The main function of erythropoietin (EPO) is in hematopoiesis where EPO stimulates increased proliferation, survival and differentiation of erythrocytic precursors in response to hypoxia. The EPO effect is mediated via binding to the EPO receptor (EPOR), which induces activation of different intracellular signaling pathways. Recombinant human EPO (rhEPO) is also used in treatment of cancer patient
A search for a Standard Model Higgs boson decaying via H -> ZZ -> l(+)l(-) nu(nu) over bar, where l represents electrons or muons, is presented. It is based on proton-proton collision data at root s = 7 TeV, collected by the ATLAS experiment at the LHC during 2011 and corresponding to an integrated luminosity of 4.7 fb(-1). The data agree with the expected Standard Model backgrounds. Upper limits
Nanowires were grown by means of a novel aerosol-based method called Aerotaxy. Here an aerosol of Au catalyst nanoparticles in N-2 is mixed with MOVPE precursors in a flow-through reactor at atmospheric pressure, whereby nanowires are produced continuously in high concentrations. We demonstrate the possibility of in situ doping of the NWs and the realization of well-controlled p-type GaAs nanowire
Generalized frequency division multiplexing (GFDM) is a new digital multicarrier concept. The GFDM modulation technique is extremely attractive for applications in a fragmented spectrum, as it provides the flexibility to choose a pulse shape and thus allows reduction of the out-of-band leakage of opportunistic cognitive radio signals into incumbent frequency space. However, this degree of freedom
Laminar burning velocities of syngas/air premixed flames, varying with H-2/CO ratio (from 5/95 to 75/25) and N-2 or CO2 dilution rate (from 0% to 60%), were accurately measured using a Teflon coated Heat Flux burner and OH-PLIF based Bunsen flame method. Experiments were carried out at atmospheric pressure and room temperature, with fuel/air equivalence ratios ranging from fuel-lean to fuel-rich.
Popular Abstract in Swedish Diabetes är en av de vanligaste folksjukdomarna och tusentals diagnostiseras med sjukdomen varje år. Det finns två typer av diabetes, typ 1 och typ 2. I typ 1 förstörs de insulin producerande β-cellerna som finns i de Langerhanska öarna av kroppens immunförsvar. β-cellerna har till uppgift att reglera blodsockernivåerna. Avsaknaden av egen insulinproduktion leder till dDiabetes affects enormous amounts of patients. In type 1 diabetes the insulin producing β cells in the islet of Langerhans are destroyed by the immune system. The β cells, which are located in the pancreas, regulate blood glucose levels. The lack of insulin production requires administration of insulin. This is accomplished by insulin injections. Even though the treatment methods have been improve
Terahertz spectroscopy is employed for the noncontact measurement of transversal mobility in InP nanowires, wherein photonic effects (waveguiding of excitation beam and propagation of terahertz beam in a complex gradient environment) were successfully deconvoluted. Monte Carlo calculations accounting for electron localization and heavy doping were used to determine electron momentum relaxation tim
The intense competition between places means that new and more differentiated marketing strategies are becoming increasingly important in order to attract visitors and other target groups. In order to be seen, gain positive media attention and put the place on the map many cities try to develop marketing concepts based on experiences, among other things. One such strategy used by many places is to
Background: The aim was to describe the feeding-and stooling patterns of infants with colic and evaluate the influence of minimal acupuncture. Methods: A prospective, randomized, controlled, blind clinical study was conducted at a private acupuncture clinic in Sweden. 90 otherwise healthy 2-8 weeks old infants, born after gestational week 36, fulfilling the criteria for infantile colic and not med
In this study we explored how men diagnosed with prostate cancer experienced their sexuality from a lifeworld perspective. One essential meaning was identified: "having the elixir of life stolen." This essential meaning had four constituents: "something that no longer exists," "the threat to manhood," "intimacy," and "staged manhood." The lifeworld for these men comprised the dynamic interaction b
We report the development of a high-level bacterial expression system for the Alzheimer's disease-associated amyloid beta-peptide (A beta), together with a scaleable and inexpensive purification procedure. A beta(1-40) and A beta(1-42) coding sequences together with added ATG codons were cloned directly into a Pet vector to facilitate production of Met-A beta(1-40) and Met-A beta(1-42), referred t
This paper describes how focus group interviews were used in a project on developing research support services. The object of the interviews was to understand the everyday lives of researchers and the obstacles they experience in their research process. Advantages and challenges of the method are discussed, e.g. the benefits of the interaction and the free form that the method allows for and the c
The aim of this pilot study was to assess the association between perceived environmental barriers and perceived participation in everyday life situations encountered by people with late effects of polio. A sample of 45 persons with clinically verified late effects of polio answered the Swedish versions of the Impact on Participation and Autonomy Questionnaire (IPA-S) and the Craig Hospital Invent
In this conceptual paper, we introduce a meso-level theoretical framework (Consumption Field Refinement) to explain the development of market systems and suggest methods for researching this development. Our framework centres on the idea that the market system consists of interlinked subsystems (consumption fields), each focused on a particular consumption activity.
Background:The digestion of sphingolipids (SL) is slow and is catalyzed by mucosal enzymes. Dietary SL was shown to inhibit cholesterol absorption and to lower plasma cholesterol, triglycerides (TG) and hepatic fat accumulation in animal models.Aim:A dairy formulation based on fractionation of buttermilk, which is enriched in milk polar lipids of which SL account for a large part is now available.
This paper explores the interaction between brand orientation and market orientation. Brand orientation is an inside-out, identity-driven approach that sees brands as a hub for an organization and its strategy. Similarly, market orientation is an outside-in, image-driven approach. Initially, brand orientation and market orientation appear to be two different strategic options. Though synergistic c
Electrode grounding resistance is a major factor affecting measurement quality in electric resistivity tomography (ERT) measurements for cryospheric applications. Still, little information is available on grounding resistances in the geophysical literature, mainly because it is difficult to measure. The focus-one protocol is a new method for estimating single electrode grounding resistances by mea
Type 1 diabetes is one of the most common chronic diseases in childhood and adolescence with an increasing incidence worldwide. It is an autoimmune disease with many autoimmune markers, where the zinc transporter 8 autoantibody (ZnT8A) is the most recent autoantibody discovered. The most important genetic susceptibility towards type 1 diabetes is found within the HLA-region on chromosome 6. We sho
