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Abstract in UndeterminedBearing in mind the potential and importance of enzymatic processes it is somewhat surprising that we are not yet able to fully exploit the possibilities that such processes offer. The main reason is that we do not know the mechanism on the molecular scale in terms of the interaction between the enzyme and the substrate or rather the assembly of substrate molecules (see Fig
Popular Abstract in Swedish För att öka förståelsen för hur ljud sprider sig och strålar från byggnadskonstruktioner utförda i lättbyggnadsteknik så behövs teoretiska beräkningsmodeller. Sådana modeller presenteras i avhandlingen. Med lättbyggnadsteknik avses konstruktioner som inte är massiva, exempelvis väggar och bjälklag bestående av trä- eller stålreglar/bjälkar. Stegljudet, det vill säga detIn order to increase our knowledge of the sound transmission and radiation processes of lightweight wall and floor structures, theoretical models are needed. Detailed models may form a valuable tool. In lightweight floor structures, impact sound insulation is perhaps the most important property to consider. This thesis presents an overview of various solution strategies that may be useful in findi
Global land-use change has drastic consequences for biodiversity leading to losses of ecological functioning, ecosystem services and human well-being. While species dependent on undisturbed natural habitat are most affected by conversion to agriculture, even populations of disturbance-tolerant species can be endangered in landscapes dominated by high-input mono-cultural cropping systems. This has
Association studies were carried out on a sample of 87 patients from Sweden who had survived a myocardial infarction (MI) at a young age and 93 age-matched healthy individuals, to compare the impact of polymorphisms (PvuII, HindIII and Serine447-Stop) at the lipoprotein lipase (LPL) gene locus on among-individual differences in plasma lipid traits and progression of atherosclerosis. Significant li
Vegetation productivity is a critical indicator of global ecosystem health and is impacted by human activities and climate change. A wide range of optical sensing platforms, from ground-based to airborne and satellite, provide spatially continuous information on terrestrial vegetation status and functioning. As optical Earth observation (EO) data are usually routinely acquired, vegetation can be m
Humanity’s ever-growing energy demands require the implementation of more sustainable ways to harvest and store energy. At the same time, the reduction of greenhouse gas emission and thus global warming remains of paramount importance. To this end, solar energy harvesting presents an attractive route towards satisfying these requirements—be that by conversion to thermal energy, electricity or to c
Breast cancer is the most common type of cancer globally. Early detection is important for reducing the morbidity and mortality of breast cancer. The aim of this study was to evaluate the performance of different machine learning models to classify malignant or benign lesions on breast ultrasound images. Three different convolutional neural network approaches were implemented: (a) Simple convoluti
There is scientific consensus that limiting warming in line with the Paris Agreement goals requires reaching net zero CO2 emissions by mid-century and net negative emissions thereafter. Because of the entrenchment of current fossil fuel energy and feedstock demand estimated in almost all global modelled scenarios, 'abated' fossil fuel and industrial process and product use (IPPU) CO2 emissions, us
Understanding monthly runoff variability, its spatio-temporal characteristics, and key drivers under climate change and human impacts is crucial for long-term water resource management. However, current knowledge remains limited, especially in high-elevation, seasonally cold regions. Focusing on 10 sub-basins along an elevation gradient (1000 to 5900 ma.s.l.) in the hydrologically complex Yalong R
Background: Recent randomized trials demonstrated that laparoscopic lavage compared with resection for Hinchey III perforated diverticulitis was associated with similar mortality, less stoma formation but a higher rate of early reintervention. The aim of this study was to compare 1-year outcomes in patients who participated in the randomized Scandinavian Diverticulitis (SCANDIV) trial. Methods: Be
Monitoring soil moisture at the Earth'surface is of great importance for drought early warnings. Spaceborne remote sensing is a keystone in monitoring at continental scale, as satellites can make observations of locations which are scarcely monitored by ground-based techniques. In recent years, several soil moisture products for continental scale monitoring became available from the main space age
Over the last decades, the impact of human activities on the global nitrogen (N) cycle has drastically increased. Consequently, benthic N cycling has mainly been studied in anthropogenically impacted estuaries and coasts, while in oligotrophic systems its understanding is still scarce. Here we report on benthic solute fluxes and on rates of denitrification, anammox, and dissimilatory nitrate reduc
We report the first successful use of miniature Global Positioning System loggers to track the ocean-going behaviour of a c. 400g seabird, the Manx Shearwater Puffinus puffinus. During three field seasons, breeding birds were tracked during the incubation and chick rearing periods on their foraging excursions from the large colony on Skomer Island, Pembrokeshire, UK. Foraging effort was concentrat
Policy-makers in the European Union (EU) have increasingly emphasised public procurement as an instrument that can be used to stimulate innovation. These developments reflect and respond to a growing concern among EU member states and regions about how to maintain competitive advantage in an economic environment increasingly subject to global competition The Lisbon goals set for the EU in 2000 req
NOx pollution from diesel engines has been stated as causing over 10 000 pre-mature deaths annually and predictions are showing that this level will increase [1]. In order to decrease this growing global problem, exhaust after-treatment systems for diesel engines have to be improved, this is especially so for vehicles carrying freight as their use of diesel engines is expected to carry on into the
The possibility to have a strongly first order electroweak phase transition, which is one of the Sakharov conditions for electroweak baryogenesis together with $\mathcal{CP}$ violation and baryon number violation, in general Two-Higgs-Doublet Models (2HDMs) is here investigated. Different kinds of $\mathbb{Z}_{2}$ breaking beyond standard assumptions are studied, in particular by allowing it to be
