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The Siemens gas turbine SGT-800 is the largest industrial gas turbine produced by Siemens Industrial Turbomachinery (SIT) offering a dry low emission (DLE) capability below 15 ppm NOx. It has a very high reliability using an annular combustor system with passive damping and 30 DLE burners. To obtain a greater understanding of the mixing process and the flame dynamics and in order to further reduce
Abstract: Background: During breast cancer progression, the epithelial to mesenchymal transition has been associated with metastasis and endocrine therapy resistance; however, the underlying mechanisms remain elusive. To gain insight into this process, we studied the transition undergone by MCF7-derived cells, which is driven by the constitutive nuclear expression of a MKL1 variant devoid of the a
This is a review of the recent publication “Pharmaceutical Innovation, Competition and Patent Law – A Trilateral Perspective”, edited by Max Planck Director Josef Drexl and Finnish scholar Nari Lee (Edward Elgar 2013, 322 p., ISBN 978 0 85793 245 7). In summary, I conclude that the editors, who also contributed with excellent papers, have succeeded very well in the difficult task of structuring, s
Abstract Since the late 1970’s, China has rapidly increased its exports of industrial products and inflow of foreign direct investment (FDI) through the use of special economic areas (SEA), which offer special benefits to foreign investors and export producers. Common criticism against these SEAs, usually states that these areas show persistent low-standard working conditions and wages to remain c
Monitoring soil moisture at the Earth'surface is of great importance for drought early warnings. Spaceborne remote sensing is a keystone in monitoring at continental scale, as satellites can make observations of locations which are scarcely monitored by ground-based techniques. In recent years, several soil moisture products for continental scale monitoring became available from the main space age
A major unanswered question in the dementia field is whether cognitively unimpaired individuals who harbor both Alzheimer's disease neuropathological hallmarks (that is, amyloid-β plaques and tau neurofibrillary tangles) can preserve their cognition over time or are destined to decline. In this large multicenter amyloid and tau positron emission tomography (PET) study (n = 1,325), we examined the
The possibility to have a strongly first order electroweak phase transition, which is one of the Sakharov conditions for electroweak baryogenesis together with $\mathcal{CP}$ violation and baryon number violation, in general Two-Higgs-Doublet Models (2HDMs) is here investigated. Different kinds of $\mathbb{Z}_{2}$ breaking beyond standard assumptions are studied, in particular by allowing it to be
This thesis deals with collusion risks in e-commerce markets based on an analysis of economic theory on structural factors facilitating collusion and empirical findings from studies and case law. It further offers an analysis of the legal status of any such collusion and a discussion on competition policy in relation to it. Whereas the legal rules governing collusion in Article 81(1) of the EC Tre
Today’s global competition forces manufacturing companies to re-evaluate their existing processes, technologies, manufactured parts and services in order to focus on strategic activities. The question whether to make or to buy goods or services represents a problem faced by many companies when deciding between keeping technologies/processes in-house or purchasing them from an outside supplier. In
Nahoj Nim has for a long time been very successful at developing, producing and selling packaging solutions for the food industry. Today, however, Nahoj Nim faces a new challenge as competitors are gaining market shares. The purchasing unit Component & Technical Consultant Purchasing (hereafter referred to as C&TCP), involved in sourcing, contracting and managing the supplier base for comp
Over the last decades, the impact of human activities on the global nitrogen (N) cycle has drastically increased. Consequently, benthic N cycling has mainly been studied in anthropogenically impacted estuaries and coasts, while in oligotrophic systems its understanding is still scarce. Here we report on benthic solute fluxes and on rates of denitrification, anammox, and dissimilatory nitrate reduc
Biogenic volatile organic compounds (BVOC) are emitted naturally from the biosphere to the atmosphere and are a part of the global carbon emissions. BVOCs are contributing to around 5-10% of the total net carbon exchange to the atmosphere. The BVOC emissions from the biosphere are mainly from plants and other organisms and consists of many different compounds, such as isoprene, monoterpenes (MT) a
Background: Global transcriptional profiling of individual cells represents a powerful approach to systematically survey contributions from cell-specific molecular phenotypes to human disease states but requires tissue-specific protocols. Here we sought to comprehensively evaluate protocols for single cell isolation and transcriptional profiling from heart tissue, focusing particularly on frozen t
As for the automotive industry, industry and academia are making extensive efforts to create autonomous ships. The solutions for this are very technology-intense. Many building blocks, often relying on AI technology, need to work together to create a complete system that is safe and reliable to use. Even when the ships are fully unmanned, humans are still foreseen to guide the ships when unknown s
Breast cancer is the most common type of cancer globally. Early detection is important for reducing the morbidity and mortality of breast cancer. The aim of this study was to evaluate the performance of different machine learning models to classify malignant or benign lesions on breast ultrasound images. Three different convolutional neural network approaches were implemented: (a) Simple convoluti
Vegetation productivity is a critical indicator of global ecosystem health and is impacted by human activities and climate change. A wide range of optical sensing platforms, from ground-based to airborne and satellite, provide spatially continuous information on terrestrial vegetation status and functioning. As optical Earth observation (EO) data are usually routinely acquired, vegetation can be m
Humanity’s ever-growing energy demands require the implementation of more sustainable ways to harvest and store energy. At the same time, the reduction of greenhouse gas emission and thus global warming remains of paramount importance. To this end, solar energy harvesting presents an attractive route towards satisfying these requirements—be that by conversion to thermal energy, electricity or to c
There is scientific consensus that limiting warming in line with the Paris Agreement goals requires reaching net zero CO2 emissions by mid-century and net negative emissions thereafter. Because of the entrenchment of current fossil fuel energy and feedstock demand estimated in almost all global modelled scenarios, 'abated' fossil fuel and industrial process and product use (IPPU) CO2 emissions, us
