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The principle of the persistent objector strikes at the heart of international law creating uncertainty over issues as how customary international law is created, whom it binds and how states actively can evade being bound by certain customary international laws. The mere existence of this principle gives rise to a great number of diverging interpretations. The study presented herein analyses the
To find the optimal by-pass road alignment in the Tlokweng Planning Area in Botswana, a multi-criteria spatial-based model is developed using the GIS-MCE approach. In respect to the environmental impact assessment (EIA) approach, in this research a set of criteria is classified under 3 themes – economic, environmental and social. To determine the criterion and theme weights and perform their aggre
Abstract This Master Thesis project was carried out at Tetra Pak Business Support (TPBuS), which is a company within the Tetra Pak group. Tetra Pak is a global company, they supply packaging solutions for the packaging industry. TPBuS main task is to support the core activities. They provide services such as goods handling, a company restaurant and a company shop for office equipment and supplies.
Detailed (222)radon (Rn-222) flux maps are an essential pre-requisite for the use of radon in atmospheric transport studies. Here we present a high-resolution Rn-222 flux map for Europe, based on a parameterization of Rn-222 production and transport in the soil. The Rn-222 exhalation rate is parameterized based on soil properties, uranium content, and modelled soil moisture from two different land
Soil organic matter (SOM) stores the largest quantity of C in terrestrial ecosystems. Most SOM can be decomposed by microorganisms and released as CO2 into the atmosphere. The remaining fraction of SOM can be resistant against microbial decomposition over centuries to millennia. Changes in the magnitude of this stable SOM pool can have a substantial effect on the atmospheric CO2 concentration and
Objectives: The aims were to identify patients with rheumatoid arthritis (RA) who had stopped drinking alcohol and compare them with patients drinking alcohol, and to explore reasons for stopping drinking alcohol. Design: A sequential explanatory mixed methods design was used. Setting: Six rheumatology clinics in Southern Sweden Better Anti-Rheumatic FarmacOTherapy cohort. Participants: A total of
Proteins are tiny chemical machines that play many critical roles in our body. Some proteins send important messages, some carry crucial supplies, some fight with invaders and protect body from diseases, some clear trash etc. Proteins are strings of hundreds and thousands of small units called amino acids. If the string is built from less than hundred amino acids, it is called a peptide. DNA, a loThe pathogenesis of Alzheimer’s disease is widely believed to be due to production and deposition of the amyloid β-peptide. Several variants of the Aβ peptide are known to exist in in vivo. Variations include mutations or additional functional groups attached to residue side chains and may affect the aggregation process. Early on-set Alzheimer’s is caused by a variety of single amino acid substitu
OBJECTIVE: To examine the cross-sectional associations between regional tau, β-amyloid (Aβ), and cortical thickness and neuropsychological function across the preclinical and clinical spectrum of Alzheimer disease (AD). METHODS: We included 106 participants from the Swedish Biomarkers for Identifying Neurodegenerative Disorders Early and Reliably (BioFINDER) study, of whom 33 had preclinical AD (A
Ciliate assemblages play a significant role in the microbial food web. The effects of environmental temperature on assemblage composition may be influenced by abiotic factors such as seasonality and disturbance, but the effects of temperature on ciliate assemblages found on different substrata have not been explored. Sandy bottoms and submerged rocks harbour dissimilar ciliate assemblages, and it
Lubricants are used in numerous applications in our society, for instance, as hydraulic fluids. When used in forestry, 60-80% of these hydraulic fluids are released into the environment. This is one of the reasons for the growing interest for developing and utilising hydraulic fluids with good environmental performance. Another driving force in the development of hydraulic fluids is to replace fos
Popular Abstract in Swedish Populärvetenskaplig sammanfattning Ledgångsreumatism (Reumatoid Artrit, RA) leder hos många patienter till omfattande ledskador, vilket kan ge upphov till behov av operation. Med tillgång till nya och bättre läkemedel för behandling av RA förefaller behovet av reumakirurgiska operationer ha minskat, åtminstone för vissa typer av ingrepp. Det är dock tydligt att det finnOrthopedic surgery is used effectively in many patients with severe rheumatoid arthritis RA). The aim of modern pharmacologic treatment is to prevent joint destruction and reduce the need for orthopedic surgery. Patient reported outcomes (PROs) are important measures of the burden of RA. A large, community based RA cohort, established in 1997, was investigated. Patients were classified according t
Background: A polymorphism in the activating component of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex, neutrophil cytosolic factor 1 (NCFI), has previously been identified as a regulator of arthritis severity in mice and rats. This discovery resulted in a search for NADPH oxidase- activating substances as a potential new approach to treat autoimmune disorders such as rh
Over the last two decades there has been a striking and continuous increase in the prevalence of obesity both in industrialized and developing countries. Despite this global consistency there is a variation within countries with a higher prevalence of obesity within rural areas. The overall aim was to explore the prevalence of obesity and factors that influence the development of obesity in a rura
Popular Abstract in Swedish I takt med att den stratosferiska ozonskikten tunnas ut når mera av solens skadliga ultraviolet-B strålning (UV-B, 280 - 320 nm) jordytan. I avhandlingen beskrivs det effekter av ökad UV-B strålning på komponenter (mossor) och processer (nedbrytning av förna, biomassa produktion, arternas samspel) i ekosystem på höga breddgrader. Experiment utfördes där en hed och en myBiologically harmful ultraviolet-B radiation (UV-B, 280-320 nm) is increasing at the Earth´s surface owing to stratospheric ozone depletion. This is of global concern due to potential impacts of enhanced UV-B radiation on the biosphere. The aim of this thesis was to investigate effects of enhanced UV-B radiation on components (bryophytes) and processes (decomposition, productivity, species interac
An open European market for goods and services, including transport services, stimulates trade, global competitiveness and economic growth. At the same time, concerns about domestic job security and the environment have sparked debate. This report should be considered a first modest contribution to a mainly unexplored area in the past. Cabotagestudien consists of a walkthrough of previous research
The present text is a theoretical framework that has been developed with the aim to generate knowledge of and policy recommendations for the promotion of integrated mobility services (IMS), with specific regard to institutional dimensions. Integrated mobility services are services where the passenger’s transport needs are met by a service that not only integrates a range of mobility services, both
© 2018 The Author(s). Background: Administration of antimicrobials to food-producing animals is regarded as a major contributor to the overall emergence of resistance in bacteria worldwide. However, few data are available on global antimicrobial use and resistance (AMR) in livestock, especially from low- and middle-income countries. Methods: We conducted a structured survey of 91 small-scale pig f
The uncertainties and sources of variation in projected impacts of climate change on agriculture and terrestrial ecosystems depend not only on the emission scenarios and climate models used for projecting future climates, but also on the impact models used, and the local soil and climatic conditions of the managed or unmanaged ecosystems under study. We addressed these uncertainties by applying di
In the evolution of bird migration, partial migration is assumed to be an important intermediate step between migration and residency. Partial migration is characterised by the existence of both migratory and resident individuals in a given population. Compared to regular migration, relatively little is known about partial migrants and their migratory performances. In my thesis, I have studied th
