Filtyp
The evolution of digital manufacturing is inherently linked with Computer Integrated Manufacturing (CIM) since 1980. CIM triggers the partial or fully automation in the industrial sector. Due to the global competitiveness and mandatory requirement of triple bottom line sustainability approach, the industries are on the verge of adapting digitalized sustainable manufacturing. The Digital manufactur
Background Colorectal cancer (CRC) remains a major global health challenge with high morbidity and mortality despite advances in detection and treatment. Dietary polyphenols are secondary metabolites widely found in plant-derived foods and beverages, and have gained attention for their potential in CRC prevention and therapy due to their diverse biological activities. Methods This review synthesiz
Arsenic contamination in soil and water poses significant health risks globally through contaminated crops. 1,2,3 Modern cultivated rice ( Oryza sativa ), particularly the subspecies japonica , accumulates high levels of arsenic. 1,3,4,5,6 This may possibly result from unintended physiological and genomic changes during rice domestication, which have significantly altered traits such as plant arch
INTRODUCTION: Amyloid-induced tauopathy drives clinical decline in Alzheimer's disease (AD). Because age and sex shape tau trajectories, defining patient-centered amyloid thresholds for tauopathy onset could facilitate pre-tauopathy AD identification and aid treatment decisions and prognosis. METHODS: By including two samples (Alzheimer's Disease Neuroimaging Initiative [ADNI, n = 301]; and 18F-AV
The intense stellar irradiation of ultra-hot Jupiters results in some of the most extreme atmospheric environments in the planetary regime. On their daysides, temperatures can be sufficiently high for key atmospheric constituents to thermally dissociate into simpler molecular species and atoms. This dissociation drastically changes the atmospheric opacities and, in turn, critically alters the temp
Group A Streptococcus (GAS) causes extensive global morbidity and rising rates of invasive disease, for which clinical outcomes remain poor despite antibiotic treatment of susceptible strains. This limitation of current therapy underscores the need for alternative or adjunctive approaches. Antibody-based interventions represent a promising but underexplored strategy. Historically, the streptococca
Many different types of insects make seasonal migrations over vast distances, typically from one broad geographical region to another, most often involving a latitudinal change in one direction in spring with a reversal of this direction in autumn. However, a small handful of these species instead migrate from an enormous geographical area to a highly specific destination they have never previousl
Globally, a substantial number of children experience various forms of parental maltreatment. Child protection agencies work to support these children and prevent further abuse or neglect, often through targeted interventions directed at the parents. Previous research has indicated that social workers may approach male and female perpetrators of maltreatment differently once a case is reported. To
Ion exchange membranes (IEMs) have consolidated applications in energy conversion and storage systems, like fuel cells and battery separators. Moreover, in the perspective to address the global need for non-carbon-based and renewable energies, salinity-gradient power (SGP) harvesting by reverse electrodialysis (RED) is attracting significant interest in recent years. In particular, brine solutions
BACKGROUND: People with a migration background are underrepresented in dementia research and disfavored in assessment and treatment, and many foreign-born individuals with dementia remain undiagnosed.OBJECTIVE: The aim of this study was to examine whether there is inequality in the clinical assessment of dementia between native and foreign-born individuals in Sweden.METHODS: Information was gather
Background: Sequencing parasite genomes in the presence of host DNA is challenging. Sequence capture can overcome this problem by using RNA probes that hybridize with the parasite DNA and then are removed from solution, thus isolating the parasite DNA for efficient sequencing. Methods: Here we describe a set of sequence capture probes designed to target 1035 genes (c. 2.5 Mbp) of the globally dist
Salinomycin, a naturally occurring polyether ionophore was recently found to selectively reduce the proportion of CD44(+)/CD24(-) cells, a phenotype associated with breast cancer stem cells. Subsequent studies from our group showed that chemical modification of the allylic C20 hydroxyl of salinomycin, located at the C-ring, can enhance the activity of derivatives against breast cancer cells over 5
BACKGROUND: Breast cancer, which is the most prevalent form of cancer among women globally, encompasses various subtypes that demand distinct treatment approaches. The tumor microenvironment and immune response are of crucial significance in the development and progression of breast cancer. Nevertheless, there has been scant evidence concerning the genes within breast cancer - specific immune cell
Background: Pain fluctuations are a characteristic phenomenon in advanced Parkinson's disease (PD), but their temporal association with motor and non-motor symptom (NMS) fluctuations remains largely enigmatic. Moreover, data on their importance for disease severity perception and health-related quality-of-life (hr-QoL) is limited. Objective: To dissect pain fluctuations with respect to pain type a
Haemolysis occurring during cardiac surgery with cardiopulmonary bypass (CPB) is assumed to be a risk factor for postoperative acute kidney injury (AKI). Plasma alpha-1 microglobulin (A1M) may have a protective role as haem scavenger. The aim of this study was to evaluate the association between AKI and the degree of haemolysis and the course of A1M concentrations during cardiac surgery, respectiv
The emergence of antibiotic resistance is a global health concern. Therefore, understanding the mechanisms of its spread is crucial for implementing evidence-based strategies to tackle resistance in the context of the One Health approach. In developing countries where sanitation systems and access to clean and safe water are still major challenges, contamination may introduce bacteria and bacterio
A paradigm shift is emerging in higher education especially regarding how universities should address personalized and collaborative mobile learning. Experiences from three international benchmarking-projects through the European Association of Distance teaching Universities (EADTU), the European Centre for Strategic Management of Universities (ESMU) and the First dual mode benchmarking club on qu
An energy system that relies on fossil fuel is not sustainable. Emissions, such as carbon dioxide, nitric oxide and corpuscles, affect the climate and pollute the air. Furthermore, the supply of oil, coal and natural gas is located a few places worldwide, which can give rise to geopolitical conflicts for access to these areas. This is not a local issue for Tjörn, nor even a national issue for Swed
Vocal learning is a critical behavioral substrate for spoken human language. It is a rare trait found in three distantly related groups of birds-songbirds, hummingbirds, and parrots. These avian groups have remarkably similar systems of cerebral vocal nuclei for the control of learned vocalizations that are not found in their more closely related vocal non-learning relatives. These findings led to
