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Tendons are known to adapt their structural and mechanical properties in response to mechanical loading, but the precise mechanisms underlying this adaptation remain poorly understood. A previous study on rat Achilles tendons compared the effect of unloading (Botox injections and orthosis) with free cage activity (full loading) and revealed that unloading impaired the mechanical response and resul
Purpose: The virtualization of work has been high on the agenda during the new millennium, increasingly so after the pandemic. In this transition, co-working spaces (CWS) are often proposed to be the future-proof solution. The purpose of this paper is to explore how hybrid and virtual solutions are portrayed in co-working literature and whether they are shaping CWS in practice. Design/methodology/
Aims Cardiac allograft vasculopathy (CAV) is a significant complication that contributes to both morbidity and mortality after heart transplantation. The aim of this study was to (i) assess if quantitative cardiovascular magnetic resonance (CMR) myocardial perfusion could detect different stages of CAV and (ii) establish a myocardial perfusion reserve (MPR) cut-off for significant CAV. Methods and
INTRODUCTION: Opioid use disorder (OUD) is the leading cause of overdose morbidity and mortality globally. Retention in opioid agonist treatment (OAT) is crucial as it effectively reduces overdose mortality among individuals suffering from OUD. Previous research on treatment retention among heroin-dependent individuals referred from needle exchange programs (NEP) to OAT is scarce, and with predict
Brazil maintains its position at the top of the global ranking of plastic producers, yet recycling efforts have been incipient. Recent data reveals an annual production of approximately 14 million tons of plastic waste, not accounting for the surge in the usage of plastic masks and related materials due to the COVID-19 pandemic. However, what remains largely unreported is that over half of post-co
Objective: To study the impact of tumour necrosis factor-α inhibitor (TNFi) therapy on the use of non-steroidal anti inflammatory drugs (NSAIDs) in patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA), and axial spondyloarthritis (axSpA) in Iceland. Method: This registry cohort study used data from the nationwide database on biologics in Iceland (ICEBIO) and the Icelandic Prescriptio
Purpose: We aimed to analyze the risk of hereditary hemochromatosis (HH) among first-generation and second-generation immigrants in Sweden using Swedish-born individuals and Swedish-born individuals with Swedish-born parents as referents, respectively. Methods: All individuals aged 18 years of age and older, n = 6,180,500 in the first-generation study, and n = 4,589,930 in the second-generation st
The consumption of plastic bags is a global problem that leads to increased concentration of plastic in the world oceans. In 2014, annual consumption of plastic carrier bags amounted to around 100 billion in the EU, which corresponds to an average of about 200 bags per person per year, of which many plastic bags are used only once and/or end up as waste in nature. This thesis is a comparative case
Background: Hormone-sensitive lipase (HSL) is expressed predominantly in adipose tissue, where it plays an important role in catecholamine-stimulated hydrolysis of stored lipids, thus mobilizing fatty acids. HSL exhibits broad substrate specificity and besides acylglycerides it hydrolyzes cholesteryl esters, retinyl esters and lipoidal esters. Despite its role in fatty acid mobilization, HSL null
Many product-based companies have identified digital services as a promising way to differentiate themselves and to stimulate future growth. However, as digital services frequently induce a business model change to a pay-per-use or subscription model, companies see themselves increasingly challenged as their revenues are progressively dependent on customers’ actual usage. This is in contrast to th
The lack of accountability for human rights violations arising out of the activities of multinational enterprises has been identified as a key impediment to the fulfillment of universal human rights and the corresponding access to remedy for victims. However, the last couple of years have witnessed an increasing movement to bridge the accountability gap on the national and international level. Th
Under de senaste decennierna har samhället genomgått en snabb teknologisk utveckling som resulterat i nya arbetssätt. Det är nu lättare än någonsin att arbeta var, när och hur man vill. Att världen drabbades av en pandemi under inledningen av 2020 accelererade den teknologiska utvecklingen. Digitala arbetssätt blev därmed vardag för majoriteten av den kontorsarbetande befolkningen. När det bevisliIn recent decades, society has undergone rapid technological development, resulting in new ways of working. It is now easier than ever to work where, when and how you want. A global pandemic at the start of 2020 accelerated technological progress. Digital ways of working thus became commonplace for the majority of the office-working population. With the evidence that remote working is productive,
The rapid growth of the global electric vehicle (EV) market has led to an increased focus on the lifecycle management of electric vehicle batteries (EVBs), particularly concerning their end-of-life (EoL) handling. The thesis explores and evaluates the implementation of reverse logistics (RL) setups for EoL EVBs of electric motorcycles in Kenya, a market that is observing an increasing EV sector bu
This study investigates the relationship between income levels and carbon dioxide emissions to examine evidence for or against the Environmental Kuznets Curve (EKC) and thereby the possibility of continued growth without ongoing carbon dioxide emissions. The paper uses data on carbon dioxide emissions derived from both territorial and consumption-based accounting methods as dependent variables. Th
