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Background: Global ischemic stroke is one of the most prominent consequences of cardiac arrest, since the diminished blood flow to the brain results in cell damage and sometimes permanently impaired neurological function. The post-arrest period is often characterised by cerebral hypoperfusion due to subacute hemodynamic disturbances, the pathophysiology of which are poorly understood. In two other

The adage “think global, act local” can be a fitting description of how to address climate change. Municipalities are often responsible for implementing the measures required to reduce greenhouse gas emissions and shift to a more climate-neutral development trajectory. However, there is a vast spectrum of municipal ambition regarding climate, and not all municipalities manage to have robust and am

This thesis investigates the volatility spillover and contagion effects to the frontier markets from the developed markets and emerging markets and tries to identify if there exists any potential volatility effect which may have impact on the investment decision of these markets. In view of the growing globalization, financial markets become increasingly interdependent and the chances for the vola

Climate change is real and imminent, and mitigation and adaptation responses are vital and urgent. Denmark is renowned for its aspirations for sustainability and concerns in that regard, especially among its citizenry. Nevertheless, high-impact lifestyles persist which put an excessive pressure on the global climate system and expose a tension between pro-environmental dispositions and actual cons

This study looks at how non-governmental organizations (NGOs) help improve education in Kenya and Bangladesh, as well as the challenges they face. It focuses on two examples: Room to Read in Kenya and Barnmissionen in Bangladesh. The study explores how NGOs use different strategies to fill gaps in education where the government cannot meet all needs. Neo-institutionalism is used to understand how

Denna uppsats analyserar hur Europeiska unionen bedömer ekvivalensen av Income Inclusion Rules (IIR) som antagits av jurisdiktioner utanför EU enligt rådets direktiv (EU) 2022/2523 av den 14 december 2022 om säkerställande av en global minimiskattenivå för multinationella koncerner och storskaliga nationella koncerner i unionen. Direktivet utgör en del av EU:s genomförande av OECD:s och G20:s PelaThis thesis examines how the European Union assesses the equivalence of Income Inclusion Rules (IIRs) adopted by non-EU jurisdictions according to Council Directive (EU) 2022/2523 on ensuring a global minimum level of taxation. As part of the EU’s adoption of the OECD/G20 Inclusive Frame-work’s Pillar Two initiative, the Directive establishes a minimum effective tax rate for large multinational en

Water-related impacts due to change in climatic conditions ranging from water scarcity to intense floods and storms are increasing in developing countries like Pakistan. Water quality and waterborne diseases like hepatitis, cholera, typhoid, malaria and dengue fever are increasing due to chaotic urbanization, industrialization, poor hygienic conditions, and inappropriate water management. The morb

Rapid deforestation is a major sustainability challenge, partly as the loss of carbon sinks exacerbates global climate change. In Cambodia, more than 13% of the total land area has been contracted out to foreign and domestic agribusinesses in the form of economic land concessions, causing rapid large-scale land use change and deforestation. Additionally, the distant drivers of local and global env

Background: We evaluated the role of cortical amyloid deposition as a factor contributing to memory dysfunction and increased risk of dementia associated with late-life depression (LLD). Methods: A total of 119 older adult participants with a current diagnosis of major depression (LLD) from the Alzheimer's Disease Neuroimaging Initiative (ADNI) Depression Project study and 119 nondepressed (ND) co

Även om vi skulle lyckas minska de globala utsläppen av växthusgaser, så finns det ett angeläget behov att anpassa samhället för att kunna motstå klimatförändringens skadliga effekter. Denna process kallas klimatanpassning. Städer står inför särskilda risker från klimatförändringen och nuvarande tillvägagångssätt, som ofta förlitar sig på tekniska lösningar och toppstyrd implementering, bedöms intEven if current attempts to reduce global greenhouse gas emissions would succeed, society-wide adjustment to the harmful effects of climate change is urgently needed. This process is known as climate adaptation. Cities face particular risks from climate change, and there is increasing evidence that traditional approaches, which have often relied on technical solutions and top-down management struc

Objective: To examine the relationship between extended high-frequency pure tone hearing thresholds (frequencies 10 to 14 kHz) and working memory capacity (WMC), inhibitory control, and cognitive flexibility. Design: Experimental study measuring correlations between different high-frequency hearing threshold measures and cognitive measures. Study: Pure tone audiometry was assessed in the extended

Data on the impact of long term treatment with immunomodulatory drugs (IMiD) on health-related quality of life (HRQoL) is limited. The HOVON-87/NMSG18 study was a randomized, phase 3 study in newly diagnosed transplant ineligible patients with multiple myeloma, comparing melphalan-prednisolone in combination with thalidomide or lenalidomide, followed by maintenance therapy until progression (MPT-T

Aims of the study: Neurological impairment after resuscitated cardiac arrest (CA) remains a significant unmet medical need. Brain ischemia associated with CA and subsequent reperfusion is evident as two fundamentally different types of damage on neuropathological examination: frank necrosis (involving all cell types) and selective eosinophilic neuronal death (SEND). These types of damage are not o

As found in the health studies literature, the levels of climate association between epidemiological diseases have been found to vary across regions. Therefore, it seems reasonable to allow for the possibility that relationships might vary spatially within regions. We implemented the geographically weighted random forest (GWRF) machine learning method to analyze ecological disease patterns caused