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To meet future challenges from an older and physically less active population innovative solutions are needed. Modern Technology against Falls (MoTFall) aims to prevent falls, increase physical activity and improve self-rated health among older people by means of an information and communication technology based system. The project has developed technology-based solutions, focusing on person-centr
Introduction: The relationship between urate and biomarkers for Alzheimer's disease (AD) pathophysiology has not been investigated. Methods: We examined whether serum concentration of urate was associated with cerebrospinal fluid biomarkers, amyloid beta (Aβ)42, Aβ40, phosphorylated tau (p-tau), total tau (t-tau), neurofilament light (NfL), and Aβ42/Aβ40 ratio, in cognitively unimpaired 70-year-ol
We recently described four distinct types of plexiform lesions in human idiopathic and familial pulmonary arterial hypertension (PAH) [1], visualising the three-dimensional lesion structure using synchrotron-based phase-contrast micro-CT (SPµCT). Two types, 1 and 2, are shunt-type lesions that connect pulmonary arteries to the bronchial circulation: type 1 to the vasa vasorum, and type 2 to peribr
BACKGROUND: There is emerging evidence that exposure to prenatal methylmercury (MeHg) from maternal fish consumption during pregnancy can differ between individuals due to genetic variation. In previous studies, we have reported that maternal polymorphisms in ABC-transporter genes were associated with maternal hair MeHg concentrations, and with children's early neurodevelopmental tests. In this st
Heart failure (HF) affects 64 million people worldwide. Despite advancements in prevention and therapy, quality of life remains poor for many HF patients due to associated target organ damage. Pulmonary manifestations of HF are well-established. However, difficulties in the treatment of HF patients with chronic lung phenotypes remain as the underlying patho-mechanistic links are still incompletely
Evidence that a 1,2-dihydroxycyclohexadienide anion is stabilized by aromatic "negative hyperconjugation" is described. It complements an earlier inference of "positive" hyperconjugative aromaticity for the cyclohexadienyl cation. The anion is a reactive intermediate in the dehydration of benzene cis-1,2-dihydrodiol to phenol. Rate constants for 3-substituted benzene cis-dihydrodiols are correlate
We investigated the relationship between lipid binding glycoprotein apolipoprotein E (apoE; gene APOE) polymorphisms (ε4 allele carriers versus no carriers = ε4+/ε4−) and trace elements (TEs) (e.g., (methyl)mercury, arsenic, lead, cadmium, selenium, manganese, copper, and zinc) in mothers (N = 223) and their new-borns (N = 213) exposed to potentially toxic metal(loid)s from seafood consumption. Th
OBJECTIVE: To estimate patient acceptable symptom state (PASS) and treatment failure (TF) threshold values for Work Productivity and Activity Impairment (WPAI) measure and EQ-5D-5L among people with hip or knee osteoarthritis (OA) 3 and 12 months following participation in a digital self-management intervention (Joint Academy®).METHODS: Among the participants, we computed work and activity impairm
IntroductionResearch evidence suggests that radiographers often rely on previous training, traditional practices, work experience and protocols developed within the department rather than up-to-date research-based evidence in their daily practice. The aim of the study was to investigate factors that might impact the development of evidence-based practice amongst radiographers in clinical public se
[The project Millora 2.0: Results 2018–2022] Based on repeated yearly surveys of the vascular plant flora in 120 hectar plots in the province of Scania, southernmost Sweden, analysed in combination with speciesspecific traits and ecological indicator values (EIVs), changes in the flora and vegetation over the last four years are reported. Many of the changes observed, such as significant increasesBased on repeated yearly surveys of the vascular plant flora in 120 hectar plots in the province of Scania, southernmost Sweden, analysed in combination with speciesspecific traits and ecological indicator values (EIVs), changes in the flora and vegetation over the last four years are reported. Many of the changes observed, such as significant increases in lightdemanding, shortlived, pollinatorind
BACKGROUND: Globally, the number of small-scale miners (SSM) is estimated to be more than 25 million, but it supports the livelihoods of around 100 million individuals. In Tanzania, the number of SSM has increased from an estimated 150,000 in 1987 to ~1.5 million in 2017. The miners are at a high risk of occupational-related health challenges. The study aimed to assess the concentrations of respir
In this study of the effects of lead on the endocrine system, 77 secondary lead-smelter workers (i.e., 62 active and 15 retired) were compared with 26 referents. Lead concentrations were determined in plasma with inductively coupled plasma mass spectrometry (i.e., index of recent exposure), in blood with atomic absorption spectrophotometry, and in fingerbone with K x-ray fluorescence technique (i.
The study was undertaken to obtain simultaneous measurements of circulating anterior pituitary hormone levels after the i.v. injection of arginine-vasopressin (AVP). Nine healthy men, mean age 31 years (range 24-41), received single blind with at least one week apart, after resting in the supine position for 30 min, AVP 0.26 microgram/kg body weight i.v. (Pitressin, Parke-Davis) or saline in rando
Although there are some epigenome-wide association studies (EWAS) of insulin resistance, most of them did not replicate their findings and are focused in populations of European ancestry limiting the generalizability. In EPIPREG (294 Europeans and 162 South Asians), we conducted an EWAS of insulin resistance in maternal peripheral blood leukocytes, with replication in Born in Bradford (n=879; 430
The surface expression of a recently described plasma glycoprotein called human complex-forming glycoprotein, hetergeneous in charge (protein HC) on a number of different human cell types was investigated. By means of direct and indirect immunofluorescence, protein HC was shown to be associated with the surface of virtually all cells of the investigated normal cell types including erythrocytes, pe
AbstractThis research aims to investigate and compare how computers work on five different workstation setups of multiple or large screens and viewing distances (27-inch and 49-inch at 70 or 90 cm viewing distance) affect muscular load in neck/shoulders, working postures, and perceived exertions of non-presbyopic participants. The electrical activity in the trapezius shoulder and trapezius neck muThis research aims to investigate and compare how computers work on five different workstation setups of multiple or large screens and viewing distances (27-inch and 49-inch at 70 or 90 cm viewing distance) affect muscular load in neck/shoulders, working postures, and perceived exertions of non-presbyopic participants. The electrical activity in the trapezius shoulder and trapezius neck muscles, a
Syftet med denna uppsats är att med hjälp av en fallstudie undersöka den interna kommunikationens betydelse innan och under en NPM förändring implementeras i en offentlig myndighet för att förändringen ska uppnås och slutföras. Detta är en kvalitativ fallstudie gjord på Länsstyrelsen Skåne där vi genomfört tio semistrukturerade intervjuer med nyckelpersoner från myndigheten. Vi har använt oss av
The concept of a circular economy (CE) has gained traction in the EU as a pathway towards sustainability. However, beyond the goal of closing resource loops there is no consensus on the key components of CE. Efforts to triangulate a definition of CE found that it is mainly a model for economic prosperity that aims to reconcile economic growth with sustainability. In 2020, the Swedish government ad
Här har vi samlat information, råd, tester och övningar inom olika områden som har betydelse för din hälsa. Hållbar hälsaEn hållbar hälsa och livsstil ger dig goda marginaler att klara av ditt arbete och ger kraft för en meningsfull fritid, vilket är gynnsamt för dig både på lång och kort sikt.Arbetsplatsen bör främja hälsosamma beteenden, vilket skapar förutsättningar för ett hållbart arbetsliv,
Studenthälsan arbetar med att främja studenters hälsa under studietiden. Vi erbjuder förebyggande insatser och stöd vid studierelaterad ohälsa. För dig som i ditt arbete möter studenter eller som arbetar med frågor som berör studenters arbetsmiljö och lika villkor ger vi råd, stöd och information. För dig som arbetar med studenterHänvisa student till StudenthälsanStudenthälsan möter studenter som
https://www.medarbetarwebben.lu.se/forska-och-utbilda/stod-till-utbildning/mota-och-stotta-studenter/studenthalsan - 2026-09-10
