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Apolipoprotein E (APOE) is distributed across various human tissues and plays a crucial role in lipid metabolism. Recent investigations have uncovered an additional facet of APOE's functionality, revealing its role in host defense against bacterial infections. To assess the antibacterial attributes of APOE3 and APOE4, we conducted antibacterial assays using Pseudomonas aeruginosa and Escherichia c

It has been suggested that intake of fatty fish may protect against both type 1 and type 2 diabetes. Hypotheses rest on the high marine omega-3 fatty acid eicosapentaenoic acid+docosahexaenoic acid (EPA+DHA) and vitamin D contents, with possible beneficial effects on immune function and glucose metabolism. Our aim was to investigate, for the first time, fatty fish consumption in relation to the ri

Abstract in French La mutilation génitale féminine (MGF) ou bien le terme neutre de plus de valeur, l'excision génitale féminine (EGF) est pratiquée un peu partout au Soudan, où environ 90% des femmes subissent le type le plus coûteux de l'infibulation, l'EGF. Une nouvelle approche pour combattre l'EGF au Soudan consiste à reconnaître l'ancienne forme cachée de l'EGF, la reinfibulation après l'accFemale Genital Mutilation (FGM) or the more value neutral term, Female Genital Cutting (FGC) is widely practised in northern Sudan, where around 90% of women undergo the most extensive form of FGC, infibulation. One new approach to combating FGC in Sudan is to acknowledge the previously hidden form of FGC, reinfibulation (RI) after delivery, when the woman is sewn back so much as to mimic virginit

Intracoronary near-infrared spectroscopy (NIRS) in ST-segment elevation myocardial infarction (STEMI) has demonstrated substantial lipid in STEMI culprit plaques. Thrombus aspiration during primary PCI reduces distal embolization and improves reperfusion. This study was performed to examine if aspiration thrombectomy reduces the lipid content of acute coronary syndrome (ACS) culprit plaques.

The identification, prevention, and prompt treatment of exacerbations are major objectives of asthma management. We looked at change in PEF, symptoms, and use of rescue beta-agonists during the 425 severe exacerbations that occurred during a 12-mo parallel group study (FACET) in which low and high doses of budesonide with and without formoterol were compared in patients with asthma. Oral corticost

En sedimenttransekt bestående av tio punkter borrades med hjälp av en ryssborr i alkärret vid Kalvöviken på Biskopsmålahalvön i centrala Blekinge. I huvudpunkten togs tre parallella 1 m långa borrkärnor. Sedimentprov togs ur borrkärnorna och undersöktes med hjälp av glödförlust, mineralmagnetiska-, makrofossil-, pollen- och strukturanalyser. Kronologin fastställdes genom två kol-14-dateringar kompA sediment transect based on ten corings were performed with a Russian peat corer in the aldercarr at Kalvöviken on the Biskopsmåla Peninsula in central Blekinge. Three parallel sediment cores were collected at the master coring point. These cores were subsampled and studied by means of loss of ignition (LOI), mineral magnetic measurements, macrofossil analysis, pollen analysis and structural anal

BACKGROUND: There was a decrease 1982-2001 in smoking during early pregnancy in Swedish women. We sought to determine whether there was a parallel decrease in socio-economic inequality in smoking. METHODS: Registry data indicating educational level and smoking status at first antenatal visit in all 2,022,469 pregnancies in Sweden 1982-2001 was analysed. Prevalence differences, odds ratios based on

The striatum is widely viewed as the fulcrum of pathophysiology in Parkinson's disease (PD) and L-DOPA-induced dyskinesia (LID). In these disease states, the balance in activity of striatal direct pathway spiny projection neurons (dSPNs) and indirect pathway spiny projection neurons (iSPNs) is disrupted, leading to aberrant action selection. However, it is unclear whether countervailing mechanisms

OBJECTIVES: To evaluate the recurrence rate after deep calf-vein thrombosis treated with 6 weeks of oral anticoagulation. DESIGN AND SUBJECTS: A 2 year follow-up of 126 consecutive patients admitted to the Department of Internal Medicine with venographically verified deep calf-vein thrombosis. RESULTS: One hundred and twenty-six patients were treated with warfarin for 6 weeks, 18 of them having ha

Reaction of [Ru-3(CO)(12)] with tri(2-furyl)phosphine, P(C4H3O)(3), at 40 degrees C in the presence of a catalytic amount of Na[Ph2CO] furnishes two triruthenium complexes [Ru-3(CO)(10){P(C4H3O)(3)}(2)] (1) and [Ru-3(CO)(9){P(C4H3O)(3)}(3)] (2) with the ligand coordinated through the phosphorus atom. Treatment of 1 and 2 with Me3NO at 40 degrees C affords the dinuclear phosphido-bridged complexes

Syftet är att beskriva och analysera hur ett kundrelationsperspektiv kan förbättra kunskapsintensiva organisationer. Frågeställningen är följande: Hur kan kundrelationsperspektivet förbättra förvaltandet av kunskap inom kunskapsintensiva organisationer? För att ta reda på detta utgår vi från Relationsmarknadsföringsteorier. De aspekter och centrala begrepp ur tankegångarna kring kundrelationer som

A noncompetitive flow immunoassay system (FIA) for the analysis of interleukin-8 (IL-8) in cell samples was developed. Affinity interaction assays based on offline incubation of excess labeled antibodies and antigen (IL-8) were carried out. The residual unbound labeled antibody was trapped in an immunoaffinity column with immobilized IL-8 while the immunocomplex, labeled antibody/IL-8, was detecte