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The peptide GSFSIQYTYHV derived from human semenogelin I forms a transparent hydrogel through spontaneous self-assembly in water at neutral pH. Linear rheology measurements demonstrate that the gel shows a dominating elastic response over a large frequency interval. CD, fluorescence and FTIR spectroscopy and cryo-TEM studies imply long fibrillar aggregates of extended β-sheet. Dynamic light scatte
Novel field effect transistors with suspended graphene gates are demonstrated. By incorporating mechanical motion of the gate electrode, it is possible to improve the switching characteristics compared to a static gate, as shown by a combination of experimental measurements and numerical simulations. The mechanical motion of the graphene gate is confirmed by using atomic force microscopy to direct
Popular Abstract in Swedish Förtroende och nationella perspektiv i multinationell krishantering: en studie av Europeiska Unionens militärstrategiska nivå Doktorsavhandling av Olof Ekman, avdelningen för Brandteknik och Riskhantering vid Lunds Tekniska Högskola (LTH), Lunds Universitet, försvarad den 9 december 2011. Tidigare forskning pekar på att förtroende i större kriser är viktigt för att saThis thesis is motivated by an increasing degree of unfamiliarity and prominence of national dimensions in multinational crisis management. The research rationale rests on the argument that trust is important but may erode when roles conflict, which in turn may result when stakeholder interests diverge. The thesis describes trust and national perspectives in terms of role conflict in an EU Operati
Introduction. Radioiodine and most cytostatic treatments are contraindicated in pregnancy. Still, inadvertent therapy does occur. Radioiodine was given to two pregnant women with Graves' disease and thyroid cancer respectively, both in their 20th gestational week. Routine pregnancy tests based on urinary β-hCG had failed to indicate pregnancy in both cases. Methods. Estimation of doses to the foet
OBJECTIVES: To study long-term patient-relevant outcomes after meniscectomy, a surgical procedure associated with a high risk of knee osteoarthritis (OA). Principal objectives were to compare traumatic with degenerative meniscal tear and partial with subtotal meniscectomy.METHODS: We studied a well-defined cohort of 205 patients who had undergone isolated unilateral meniscectomy between 1983 and 1
The mechanical integrity of tin-doped indium oxide (ITO) thin films sputtered onto a high temperature aromatic polyester developed for flexible display applications was investigated by means of tensile experiments equipped with electrical measurement, and carried out in-situ in an optical microscope. Attention was paid to the influence of ITO thickness, composition and crystalline microstructure,
High-resolution digital Holter recording was carried out in 21 patients (15 men, 64 +/- 12 yr) with chronic atrial fibrillation. Dominating atrial cycle length (DACL) was derived by frequency domain analysis of QRST-reduced electrocardiograms. Daytime mean DACL was 150 +/- 17 ms, and nighttime mean was 157 +/- 22 ms (P = 0. 0002). Diurnal fluctuation in DACL differed among patients: it tended to b
The pretreatment of softwood with sulfuric acid impregnation in the production of ethanol, based on enzymatic hydrolysis, has been investigated. The parameters investigated were: H2SO4 concentration (0.5-4.4% w/w liquid), temperature (180-240 degrees C), and residence time (1-20 minutes). The combined severity (log Ro-pH) was used to combine the parameters into a single reaction ordinate. The high
Objective: Several biological activities have been ascribed to islet amyloid polypeptide (IAPP). However, their physiological relevance remains unclear. Previous studies in rats with exogenous administration of IAPP suggest that the peptide may increase splanchnic vascular resistance and redistribute the blood flow within the pancreas to the islets. In this study, the use of IAPP-deficient mice al
BACKGROUND: The role of long-acting, inhaled beta2-agonists in treating asthma is uncertain. In a double-blind study, we evaluated the effects of adding inhaled formoterol to both lower and higher doses of the inhaled glucocorticoid budesonide. METHODS: After a four-week run-in period of treatment with budesonide (800 microg twice daily), 852 patients being treated with glucocorticoids were random
Natural radiative lifetimes have been measured along the 6sns S-3(1) (n=7-10) and 6snd D-3(1) (n=6-11) Rydberg series of neutral mercury using time-resolved laser-induced fluorescence spectroscopy in a laser-produced mercury plasma. The states of Hg I investigated in the present work were populated from the ground state by a stepwise excitation process. Relativistic Hartree-Fock calculations, incl
A new chromatographic method based on affinity supermacroporous monolithic cryogels is developed for binding and analyzing inclusion bodies during fermentation. The work demonstrated that it is possible to bind specific IgG and IgY antibodies to the 15 and 17 amino acids at the terminus ends of a 33 kDa target protein aggregated as inclusion bodies. The antibody treated inclusion bodies from lysed
α1-microglobulin (A1M) is a 26 kDa plasma and tissue protein with reductase activity and radical- and heme-binding anti-oxidative functions. In addition, exposure of A1M to hemoglobin has been shown to induce proteolytic elimination of a C-terminal tetrapeptide yielding a heme-degrading form, truncated A1M (t-A1M). Myeloperoxidase (MPO), a heme-containing enzyme that catalyzes the production of fr
CCAAT-enhancer binding protein β (C/EBPβ) is a transcription factor that has a critical role in mammary gland development and breast cancer progression. Loss of C/EBPβ increases metastatic dissemination of mouse mammary tumor cells. However, the mechanism by which C/EBPβ expression affects metastasis formation remains unknown. This study aims at determining the relationship between C/EBPβ and surv
As most manufacturing companies Alfa Laval needs to find new ways to differentiate by shifting the current product focus towards a more service oriented approach. Many manufacturing companies find it difficult to increase service revenues successfully. High investments in extending the service business do not result in the expected higher returns, providing a service paradox. To overcome the parad
Värdebaserad styrning utgörs av en samling principer, vilka ska ge en vägledning för att mäta prestationer, allokera resurser samt sätta finansiella mål. Detta görs utifrån den grundläggande förutsättningen att aktieägarvärde skapas när avkastningen överstiger investerarens kapitalkostnad. För att lyckas med implementeringen och den fortsatta tillämpningen av VBM anser vi att företaget bör följa n
Syftet med uppsatsen är att beskriva och analysera välkända strategimodellers applikationsförmåga för de specifika förutsättningar som tjänsteföretag inom storhushåll verkar inom. Metoden som vi valt är kvalitativ och materialet som används tar sin utgångspunkt i sekundärdata i form av offentliga och institutionella källor från kända strategiforskare och branschspecialister. Uppsatsen utgår teorim
