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In the setting of transplantation, T cells are deliberately depleted to prevent allograft rejection. However, this IL-7 activates the accelerated proliferation of effector memory T cells, which are the predominant mediators of graft rejection. Multipotent adult progenitor cells (MAPC) have been previously shown to modulate the response of T cells to IL-7, in vitro but not in vivo. Here, for the fi

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Yacon (Smallanthus sonchifolius (Poepp. and Endl.) H. Robinson) is a storage root originally grown in the Andean highlands. The fresh roots are perishable and quickly turn brown during handling and processing. Aiming to prolong shelf-life and to preserve the antioxidant compounds in yacon roots, 3 mm thick yacon slices were dried in a drying cabinet at 40, 50, and 60 degrees C to a moisture conten

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Syfte: Syftet är att utveckla en modell för värdering av företag i konkurs och där avsikten är att driva företaget vidare efter genomförd konkurs. Metod: Vår uppsats grundar sig främst på empirin och kan därför sägas ha en induktiv ansats. Vi har använt oss av kvalitativa metoder där vi har intervjuat personer som har god kännedom om företagsvärdering samt nyckelpersoner hos två företag. Företagen

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Huvudtes: Hur kan det komma sig att de flesta företag inom besöksnäringen väljer att rekrytera internt? Frågeställning: Inom besöksnäringen är den externa rekryteringen av chefspositioner begränsad: - Varför föredrar företagen inom besöksnäringen att rekrytera internt? Syfte: Syftet med uppsatsen är att undersöka hur och i vilken utsträckning företag i besöksnäringen rekryterar. Vi vill även belys

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Chronic pain is a prevalent and debilitating condition, conveying immense human burden. Suffering is caused not only by painful symptoms, but also through psychopathological and detrimental physical consequences, generating enormous societal costs. The current treatment armamentarium often fails to achieve satisfying pain relief; thus, research directed toward elucidating the complex pathophysiolo

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Autoantibodies to GAD65 (GAD65Ab) are prominent in type 1 diabetes. These autoantibodies may be present both years before and after the clinical diagnosis of type 1 diabetes and are widely used as a marker for the disease. Recently it has been demonstrated that progression to type 1 diabetes is accompanied by GAD65Ab epitope maturation. Here we examine whether autoantibody maturation processes als

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The authors sought to non-invasively defect changes in atrial fibrillation rhythm during autonomic provocative maneuvers. Digital Holter from 23 patients with chronic AF before and after active postural change were subjected to routine editing, and then underwent QRS and T wave subtraction, leaving pure atrial fibrillatory records. Spectral analysis by autoregressive method was performed on this r

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A fracture risk assessment tool (FRAX (TM)) is developed based on the use of clinical risk factors with or without bone mineral density tests applied to the UK. Introduction The aim of this study was to apply an assessment tool for the prediction of fracture in men and women with the use of clinical risk factors (CRFs) for fracture with and without the use of femoral neck bone mineral density (BMD

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Using a choice experiment, this paper investigates how Swedish citizens value three environmental quality objectives. In addition, a follow-up question is used to investigate whether respondents ignored any attributes when responding. The resulting information is used in model estimation by restricting the individual parameters for the ignored attributes to zero. When taking the shares of responde

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Tissue factor pathway inhibitor 2 (TFPI-2) is a matrix-associated serine protease inhibitor with an enigmatic function in vivo. Here, we describe that TFPI-2 is present in fibrin of wounds and also expressed in skin, where it is up-regulated upon wounding.

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Models of community organization involve variations of the top-down (predator control) or bottom-up (nutrient limitation) hypotheses. Verbal models, however, can be interpreted in different ways leading to confusion. Therefore, we predict from first principles the range of possible trophic level interactions, and define mathematically the instantaneous effects of experimental perturbations. Some o

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Cytomegalovirus (CMV) has been implicated in the pathogenesis of atherosclerosis. Abdominal aortic aneurysm is regarded traditionally as a consequence of atherosclerosis. Several microorganisms have been suggested as possible contributing factors for the development of abdominal aortic aneurysm. The relevance of CMV in the processes underlying the development, expansion, and rupture of abdominal a