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PURPOSE: Compare the radiological characteristics of screening images preceding interval cancers that occurred in women screened with digital breast tomosynthesis (DBT) plus digital mammography (DM) vs. those in women screened with DM alone.MATERIALS AND METHODS: From two randomized trials comparing DBT + DM vs. DM, 91 (43 from DBT + DM arm and 48 from DM arm) images preceding interval cancers and

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How do political blocs form, consolidate, and dissolve? And can we trace these dynamics through the language of parliamentary debate? We address these questions by analyzing speeches in the Swedish Riksdag, using supervised machine learning to examine changes in rhetorical alignment among parties. Adapting classification methods developed for two-party systems to a multiparty context, we assess rh

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Notation frameworks have long existed to help structure propositional logic, and to map out philosophical arguments. Similar frameworks exist for outlining long texts and scaffolding manuscript drafting. These frameworks are helpful in structuring texts and developing drafts, yet can still leave the draft with hidden incoherence. To address this gap I propose ArgMap, a notation system based on cat

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In this paper, we have studied the sensitivity of the ESSnuSB far detector to supernova neutrinos. ESSnuSB is a proposed long-baseline neutrino experiment in Sweden, which will use a 538 kt water Cherenkov detector to probe the leptonic phase δCP by studying the second oscillation maximum. However, given the very large detector volume, it will have an excellent sensitivity to supernova neutrinos i

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The first generation of medical artificial intelligence (AI) was judged on whether algorithms could match clinicians. The next generation should be judged on whether carefully designed human–AI systems can improve patient outcomes.

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This thesis investigates the use of performance bounds in radar signal processing, with particular emphasis on the Cramér-Rao bound (CRB) and its misspecified and Bayesian variants, the MCRB and the BCRB. These bounds characterize fundamental limits on estimation accuracy and can therefore be used to assess the performance attainable under a given signal model. However, they can also be used prosp

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Background: Adenosquamous carcinoma of the pancreas (ASCP) is a rare and aggressive subtype of pancreatic cancer with a dismal prognosis. Futility in ASCP has been inadequately studied. The aim is to assess the incidence of futility in ASCP cases within a European cohort. Methods: Retrospective, multicenter European study including all consecutive patients who underwent surgery for ASCP between 20

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We address how surface topology controls the multiscale flow alignment of cellulose nanocrystal (CNC) suspensions using a single in-situ experiment that combines rheology, polarized light imaging (PLI), and small-angle X-ray scattering (SAXS). Across a series of azetidinium-based dialkyl linker topologies, we resolve the propagation of alignment from the mesoscale (PLI) to the nanoscale (SAXS). Wh

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At MAX IV pixelated area detectors are operated at high frame rates to take advantage of the X-ray beam properties available from the fourth generation synchrotron in scattering, diffraction and imaging applications. A variety of photon counting and charge integrating detectors and sCMOS cameras have been integrated into a common data acquisition (DAQ) system in which data are streamed to a centra

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In an internet age when a viral sensationalist story gains far more traction than a nuanced and balanced discussion, we have become used to some politicians, media and web-based influencers bending the truth to create a misguided or distorted narrative that many people unquestioningly believe. This should never happen in science, but even here standards are sadly deteriorating. In my editorial I w

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Context. The present-day spatial and kinematic distribution of stars in the Milky Way provides key constraints on its internal dynamics and evolutionary history. However, identifying the correct tracers that highlight the mechanisms is far from straightforward. The best probes are stars that stand out in terms of kinematics, chemistry, or age compared to the underlying population to which they bel

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TiSe2 has long been considered one of the best candidate materials to host the elusive excitonic insulator (EI) phase. However, a finite coupling to the lattice can generically be expected, while a lack of "smoking-gun"signatures for the importance of the electron-hole interaction in driving the phase transition has rendered it challenging to distinguish the EI from the conventional charge-density

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Construction with timber is becoming increasingly popular, partially due to its environmental benefits in comparison to steel and concrete. This is especially true for cross-laminated timber (CLT) panels an engineered wood product consisting of stacked timber lamellae oriented perpendicu-larly to each other. CLT panels have high stiffness in comparison to its mass, which leads to a sensitivity to

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Radicalization is most often seen as a gradual process that may or may not lead to radical or extreme behaviors such as terrorism. Theories on the radicalization process often highlight the potential role of social exclusion in the propensity for radicalization. We here present some of the major radicalization theories and discuss exclusion as a common denominator that could trigger a radicalizati

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DNA replication relies on precise coordination between proteins, including the sliding clamp proliferating cell nuclear antigen (PCNA), which encircles DNA to interact with key players in replication and repair. While biochemical studies have demonstrated interactions between PCNA and DNA polymerases δ and ε during DNA synthesis, the functional role of the Pol ε–PCNA interaction in vivo, particula

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People often draw inferences from sequences of past performance, sometimes perceiving patterns even in random outcomes. This has fueled debates regarding phenomena such as the hot hand and gambler’s fallacies. With the growing use of artificial intelligence (AI) systems for forecasting and decision support, it becomes important to understand how people form beliefs from sequences of outcomes attri