Sökresultat

BACKGROUND: Periampullary cancer is a term for cancers arising in or in close proximity to the pancreas. Pancreatic cancer is the 3rd leading cause of cancer death for both sexes and while surgery is the only option for cure, chemotherapy is given in both the adjuvant and palliative settings. The aim of this study was to investigate any sex and gender differences in patients with pancreatic and ot

During the summer of 2018, a widespread drought developed over Northern and Central Europe. The increase in temperature and the reduction of soil moisture have influenced carbon dioxide (CO 2) exchange between the atmosphere and terrestrial ecosystems in various ways, such as a reduction of photosynthesis, changes in ecosystem respiration, or allowing more frequent fires. In this study, we charact

In studies recruited on a voluntary basis, lack of representativity may impair the ability to generalize findings to the target population. Previous studies, primarily based on surveys, have suggested that generalizability may be improved by exploiting data on individuals who agreed to participate only after receiving one or several reminders, as such individuals may be more similar to non-partici

The birth prevalence of cleft lip and/or palate (CL/P) varies globally, and regional differences have previously been observed within Sweden. Updated data on CL/P birth prevalence is needed and has been requested nationally and internationally. This study investigated regional differences and temporal trends in the birth prevalences of CL/P and specific cleft subtypes across Sweden’s six health ca

The AU Microscopii planetary system is only 24 Myr old, and its geometry may provide clues about the early dynamical history of planetary systems. Here, we present the first measurement of the Rossiter–McLaughlin effect for the warm sub-Neptune AU Mic c, using two transits observed simultaneously with the European Southern Observatory’s (ESO’s) Very Large Telescope (VLT)/Echelle SPectrograph for R

Aims. We aim to observe the transits and occultations of WASP-33 b, which orbits a rapidly rotating δ Scuti pulsator, with the goal of measuring the orbital obliquity via the gravity-darkening effect, and constraining the geometric albedo via the occultation depth. Methods. We observed four transits and four occultations with CHEOPS, and employ a variety of techniques to remove the effects of the

Context. AU Mic is a very active M dwarf star with an edge-on debris disk and two known transiting sub-Neptunes with a possible third planetary companion. The two transiting planets exhibit significant transit-timing variations (TTVs) that are caused by the gravi tational interaction between the bodies in the system. Aims. Using photometrical observations taken with the CHaracterizing ExOPlanet Sa

High-grade serous ovarian cancer (HGSOC) is the most prevalent and aggressive subtype of ovarian cancer. The combination of late-stage diagnosis and the tendency to exhibit resistance to existing treatments highlights a critical gap in effective therapeutic options. There is thus a need for novel strategies for targeting HGSOC, particularly in its advanced stages. To address this gap, we developed

Transformer models pre-trained on self-supervised tasks and fine-tuned on downstream objectives have achieved remarkable results across a variety of domains. However, fine-tuning these models for clinical predictions from longitudinal medical data, such as electronic health records (EHR), remains challenging due to limited labeled data and the complex, event-driven nature of medical sequences. Whi

Road traffic pollution is one of the most important factors among other environmental factors that influence the roadside vegetation. The present research examines the impact of motorway flyovers and at-grade roads on air pollution (PM10, SOx, NOx, and air quality index (AQI)) and roadside vegetation in Dehradun by considering the important biochemical parameters such as chlorophyll, ascorbic acid

This paper introduces a novel diffusion-based method for learning representations from categorical data. Conditional diffusion models have demonstrated their potential to extract meaningful representations from input samples. However, they often struggle to yield versatile, multi-task information, limiting their adaptability to unforeseen tasks. To address this, we propose a cycle conditioning app

Surface water pollution consists of various pollutants like heavy metals (Cu, Cr, Pb, and Ni), metalloids (Se, As, and Ag), and organic pollutants (dyes, antibiotics, pharmaceuticals, pesticides, and phenolic compounds). The escalating issue of water pollution requires innovative solutions for mitigation and climate resilience. Although various advanced techniques are being developed for removing

High fidelity fluid simulations have important applications in science and engineering, examples include numerical weather prediction and simulation aided design. Discontinuous Galerkin (DG) methods are promising high order discretizations for simulating unsteady compressible fluid flow in three dimensions. Systems arising from such discretizations are often stiff and require implicit time integra

The evolutionary dynamics of diurnal Aletis moths (Lepidoptera: Geometridae: Sterrhinae) in the Afrotropics have been obscured by their allopatric distributions, significant inter- and intraspecific variation in adult and caterpillar phenotypes, and involvement in complex mimicry systems. Extensive phenotypic disparity, alongside conserved genital morphology and a lack of suitable material for gen

Objectives: Mammographically spiculated breast cancer is frequently less aggressive than cancers with alternative appearances. This study aims to investigate whether the degree of spiculations relative to the tumor mass on mammography, termed the spic mass ratio (SMR), is associated with breast cancer characteristics and survival. Materials and methods: This retrospective exploratory single-center

Rates of molecular, phenotypic, and lineage diversification typically scale negatively with time interval of measurement, raising longstanding questions about time-dependency of evolutionary processes. These patterns and their potential meaning have recently re-entered evolutionary discussions. In this Perspective, we revisit the general challenges in interpreting rate–time relationships. Much app

The causal role of pollinators in driving the divergence of plant traits is a fundamental tenet of angiosperm evolution, providing hallmark examples of evolution in response to natural selection. However, it remains unclear how geographic variation in pollinator assemblages relates to the divergence of pollination traits in pollination-generalized plants. We characterized pollinator assemblages th

Memories link elements across event boundaries, integrating overlapping content experienced at different times and places. Such memory representations are thought to rely on memory integration mechanisms. The present study used multivariate pattern analysis (MVPA) of electroencephalographic (EEG) data to elucidate the temporal dynamics of integrative encoding memory processes. Memory integration w