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A flexible method of preparing and macroscopically aligning nanoparticles of crystalline silver into millimeter long fibers is presented. The approach utilizes the dual functionality of a reverse hexagonal liquid crystalline template containing a built-in reducing agent facing the aqueous domain. The method is advantageous in that its slow kinetics allows for a thorough introduction of a silver sa
Objective: To compare the healthcare costs and effects of budesonide/formoterol in,a single inhaler with those of budesonide and formoterol monotherapies, and placebo, in a multinational study in patients with chronic obstructive pulmonary disease (COPD), National Heart, Lung and Blood Institute (NHLBI)/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) stages III or IV. Previous an
A long chain of pulse-coupled oscillators was studied. The oscillators interacted via a phase response curve similar to those obtained from pacemaker cells in the heart. The natural frequencies were random numbers from a distribution with finite bandwidth. Stable frequency-entrained states were shown always to exist above a critical coupling strength. Below the critical coupling, the probability t
We review some work done by us calculating matrix elements for Kaons. Emphasis is put on the matrix elements which are relevant to predict non-leptonic Kaon CP violating observables. In particular, we recall our results for the (B) over cap (K) parameter which governs the (K-0) over bar - K-0 mixing and update our results for epsilon(K)' including estimated all-higher-order CHPT corrections and th
We study oscillator chains of the form phi(k)=omega(k)+K[Gamma(phi(k-1)-phi(k))+Gamma(phi(k+1)-phi(k))], where phi(k)is an element of[0,2pi) is the phase of oscillator k. In the thermodynamic limit where the number of oscillators goes to infinity, for suitable choices of Gamma(x), we prove that there is a critical coupling strength K-c, above which a stable frequency-entrained state exists, but be
Altered levels of enzymes in the central carbon metabolism in Streptococcus thermophilus increased the exopolysaccharide (EPS) production 3.3 times over that of the parent strain. The influence of enhanced EPS production on the rheological properties of fermented milk is described for engineered strains of S. thermophilus which produce different levels of EPSs.
Hearing function lost by degeneration of inner ear spiral ganglion neurons (SGNs) in the auditory nervous system could potentially be compensated by cellular replacement using suitable donor cells. Donor cell-derived neuronal development with functional synaptic formation with auditory neurons of the cochlear nucleus (CN) in the brainstem is a prerequisite for a successful transplantation. Here a
Bronchoalveolar lavage was performed in 51 patients with sarcoidosis and in 21 healthy nonsmokers. The concentration of fibronectin was significantly higher (p less than 0.001) in lavage fluid from sarcoid patients (median 267 micrograms.l-1) than in that of controls (46 micrograms.l-1). Furthermore, a significantly higher concentration of fibronectin was found in patients with active disease than
Cathelicidins are a family of diverse antimicrobial peptides found in granules of mammalian neutrophils. Cathelicidins are active against a broad range of microbes in different environments. Aside from their antimicrobial activity, cathelicidins possess other biological properties including cytotoxic activity towards mammalian cells. Several studies have shown that the amino acid sequence of cathe
We develop a density-functional theory for polydisperse polymer fluids satisfying the Schulz-Flory distribution. The resulting equations are remarkably simple and quickly solved, the computational effort scaling with the polydispersity index, rather than the average molecular weight. Equilibrium, or "living", polymers enter naturally as very polydisperse samples. We illustrate the importance of po
Critical to the successful application of deep brain stimulation for the treatment Parkinson's disease is the proper selection of patients who will reliably benefit from this procedure and the successful evaluation of the responses obtained. This review will discuss the various factors influencing patient selection and summarize the recommended approach to patient assessment by using the Core Asse
The ionizable amino acid side chains of proteins are usually located at the surface. However, in some proteins an ionizable group is embedded in an apolar internal region. Such buried ionizable groups destabilize the protein and may trigger conformational changes in response to pH variations. Because of the prohibitive energetic cost of transferring a charged group from water to an apolar medium,
Acute synovitis was induced in rabbit knee joints by intraarticular injection of preformed bovine serum albumin (BSA) -anti BSA immune complexes (ICs). Polymorphonuclear granulocytes (PMNGs) which had migrated into joints injected with ICs were degranulated and contained ICs as revealed by electron microscopy and were activated as revealed by the measurement of chemiluminescence (CL). In contrast,
Random Boolean networks, the Kauffman model, are revisited by means of a novel decimation algorithm, which removes variables that cannot be relevant to the asymptotic dynamics of the system. The major part of the removed variables have the same fixed state in all limit cycles. These variables are denoted as the stable core of the network and their number grows approximately linearly with N, the nu
Coexistence conditions for prewetting and layering at a hard surface in additive hard sphere polymer solutions, where the solvent particles are smaller than the monomers, have been calculated by density functional methods. Various chain lengths and pressures have been investigated. An unexpected finding is that prewetting in these systems may proceed below the bulk critical pressure. We rationaliz
The human neuroblastoma cell line SH-SY5Y/TrkA differentiates in vitro and acquires a sympathetic phenotype in response to phorbolester (activator of protein kinase C, PKC) in the presence of serum or growth factors, or nerve growth factor (NGF). We have now investigated to what extent phorbolester and NGF cause activation of Ras and Raf-1 and the involvement of PKC in this response in differentia
