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Background: Adjunctive corticosteroid therapy appears to be beneficial for adults with severe community-acquired pneumonia (CAP), but data on Mycoplasma pneumoniae CAP are limited. This study aimed to evaluate if adjunctive betamethasone reduced time to resolution of hypoxaemia in adults hospitalised with M. pneumoniae CAP. Methods: An open-label, multicentre, randomised, controlled trial was cond
Up to recently mobile gamma spectrometry has mostly been performed with NaI(Tl)-based detector systems. However lately the interest of using HPGe(High Purity Germanium)-based systems have increased and one has realised that the excellent energy resolution of HPGe-detectors, in combination with the possibility to manufacture larger crystals than before, is an advantage not only when performing in s
Background: Data from 1998 showed that CT represents about 10% of all the diagnostic X-ray examinations and almost 70% of the total radiation dose from medical diagnostic examinations in Sweden. Because of this there is a strong need to minimize the radiation dose and adapt the dose to each patient’s examination area and anatomy. Today practically all-modern CT systems are delivered with automatic
Introduction: The purpose of this study was to develop a technique for automatic segmentation based on Fourier descriptors for separating smooth objects from the background in SPECT-images. The aim of the segmentation method was to be able to automatically outline kidneys in SPECT-images of patients undergoing radionuclide therapy with 177Lu-DOTATATE. The potential advantage of combining SPECT- an
The international relations has been marked with the increased intra state ethnic conflicts which are able to cause huge humanitarian disasters and harbour instability and various threats for the international community. As a result, conflict resolution as a long term process combining social, economic and political levels and activities concerning structural change has been advocated in recent ye
IMPORTANCE: Randomized controlled trials (RCTs) in children and adolescents provide evidence for patients, families, researchers, clinicians, regulators, funders, policymakers, and other interest holders to inform decisions about health care interventions and improve outcomes for young patients and their families. To critically evaluate, interpret, and apply trial results, readers require access t
Functional p53 protein is essential for the cellular response to drug-induced DNA damage. We investigated p53 accumulation in tumour specimens from premenopausal breast cancer patients who were randomised to adjuvant chemotherapy (CMF) or postoperative radiotherapy. Of the tumours from 139 patients, 20 showed abnormal accumulation as judged with immunohistochemistry (> 10% positive tumour cells).
In a large multicentre sample of cognitively normal subjects, as a function of age, gender and APOE genotype, we studied the frequency of abnormal cerebrospinal fluid levels of Alzheimer's disease biomarkers including: total tau, phosphorylated tau and amyloid-β1-42. Fifteen cohorts from 12 different centres with either enzyme-linked immunosorbent assays or Luminex® measurements were selected for
The majority of genetic risk variants for type 2 diabetes (T2D) affect insulin secretion, but the mechanisms through which they influence pancreatic islet function remain largely unknown. We functionally characterized human islets to determine secretory, biophysical, and ultrastructural features in relation to genetic risk profiles in diabetic and nondiabetic donors. Islets from donors with T2D ex
In this presentation we report the results of our systematic review of recent empirical studies that focus on making use of the scholarship of teaching and learning to support the development of university teaching. Given its potential as a strategy for individual development and, as importantly, for a university’s “aggregated ability to support student learning” (Mårtensson, Roxå, & Olsson, 2
Storm surges combine the power of two natural hazards, strong winds and flooding, and can have devastating effects on people, infrastructure, and nature in coastal areas. Ongoing global changes, including rising sea levels and shifting storm patterns, are expected to increase both the frequency and amplitude of such events in the future. There are, however, significant regional variations and someStorm surges combine the power of two natural hazards, strong winds and flooding, and can have devastating effects on people, infrastructure, and nature in coastal areas. Ongoing global changes, including rising sea levels and shifting storm patterns, are expected to increase both the frequency and amplitude of such events in the future. There are, however, significant regional variations and some
Popular Abstract in English Nanoscience and nanotechnology have existed in this world before scientists actually coined the terms. Nature around us and human beings themselves are all made of nanomaterials (1-100 nm), such as DNA, proteins, liposomes, and enzymes. These building blocks possess molecular recognition properties, resulting in their self-assembly to form various two- and three-dimensiMolecularly imprinted polymers (MIPs) are artificial receptors made by imprinting template molecules in a polymer matrix followed by their removal through washing to obtain a specific and selective template cavities. This property of the MIPs have made them a very efficient material for diverse applications such as chromatography, purification, drug sensing, etc. Recently, zero-dimensional polymer
Popular Abstract in Undetermined All of our present information technology culture with computers, internet, smart-phones, Bluetooth links, 3D-Tv, iPad tablets, programmable washing/cooking machines, car engines, navigation computers, etc. (the list goes on and on) is based on small electrical circuits. The smaller these circuits can be made, the faster and the better microelectronics can perform.Present-day electronics employ circuits of smaller and smaller dimensions, and today the length scales are so small that the laws of physics which rule micro-cosmos, quantum mechanics, become directly important. This thesis reports on theoretical work on electron transport in different nanostructures. We have studied semiconductor quantum wells, layered materials where each layer can be only a few
Popular Abstract in Swedish Avhandlingen behandlar det nytestamentliga Judasbrevets texthistoria. Monografin inleds med en översikt av textforskningen på de Katolska Breven i allmänhet och Judasbrevet i synnerhet, från 1800-talet och fram till nutid. Mot bakgrund av det tecknade forskningsläget beskriver så författaren studiens upplägg och syfte, samt antyder några av resultaten. Det handlar främsThis study treats the textual tradition of the Epistle of Jude. After an introductory survey of earlier text-critical research, the two main purposes of this investigation are formulated: to gather and to analyze the complete textual evidence of the Epistle of Jude. The first task, to gather the evidence, involves the collation of all Greek continuous text MSS of the Epistle of Jude. The evidence
Popular Abstract in Swedish Kambrium är en tidsperiod i jordens historia som sträckte sig från 542 till 488 miljoner år sedan. Denna period kan vidare delas in i tre epoker: tidigkambrium, mellankambrium och furongian. I kambriums inledningsskede ägde en intensiv och snabb utveckling av livet rum och det var under denna tid som i stort sett alla kända djurstammar utvecklades. Denna viktiga händelsThis thesis is based on studies of upper middle Cambrian through Furongian strata in Scandinavia with focus on trilobite biostratigraphy, taxonomy, paleoecology, and intercontinental correlation. The material studied derives mainly from Västergötland and Scania, southern Sweden. Three new trilobite species are described: Macropyge (Promacropyge) scandinavica, Elkanaspis kinnekullensis, and Parabol
Gamma-ray lines from Sn-103 have been identified for the first time using EUROBALL and ancillary detectors. The level scheme of Sn-103 has been established by means of particle-gated gamma gamma coincidences. The energy spacing between the g(7/2) and d(5/2) neutron single-particle orbitals is determined from the excited states in Sn-103.
Excited states of Cd-101 were studied in the reaction Ni-58(Cr-50,2p alpha n)Cd-101. The NORDBALL array with a Neutron Wall and a Silicon Ball was employed for the detection of gamma-rays and evaporated particles, The level scheme of Cd-101 was significantly extended, Shell-model calculations were performed and the excited states were interpreted in terms of neutron particle and proton hole excita
Den hälsomässiga effekten som rapporteras i samband med sjuka-hus syndromet (SBS), vars orsak är okänd, kan betraktas som ett mönster av icke specifika symptom såsom irritationer i ögon, näsa och mun, upplevelser av torra sletnhinnor och hud, hudrodnad, mental trötthet och upplevelse av svag men ihållande lukt. Aven exponeringar i inomhusluften kan beskrivas som ett mönster av en mängd olika ämnen
Excited states in the very neutron deficient odd cadmium isotopes Cd-99, Cd-101 and Cd-103 are discussed in terms of the nuclear shell model. Systematics of excited states in Cd99-109 is presented.
