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Energieffektivt- och miljömedvetet byggande – i ljuset av investeringsstöd för nyproduktion och renovering

This is a master thesis where I investigate if there is an environmental awareness, willingness and commitment in the municipal housing companies to reduce the energy use in the building sector. Furthermore I investigate if the concept passive house or some other type of low - energy houses are used as measures. The government has imposed a state investment. The main purpose of the investment su

LYST-intracting protein (LIP5) expression, purification and affinity analysis with Aquaporin 2

Har du tänkt på att du behöver kissa oftare än vanligt när du har druckit öl? Eller när du druckit te eller kaffe? Detta beror på ett hormon som heter vasopressin och som produceras i hypofysen. Vassopressin är en slags signal till njurarna att återvinna mer vatten från urinen. Koffein och alkohol påverkar hypofysen så att den producerar mindre vasopressin vilket gör så att mer vatten hamnar i uriAquaporin 2 (AQP2) acts as a water channel in the apical membrane of principal renal cells in the collecting ducts of the kidney. Upregulation is controlled by stimulation of these cells with vasopressin. Downregulation of the presence of AQP2 in the membrane occurs through ubiquitination and then sorting of the protein via the ESCRT-I, -II and –III complexes into the Multivesicular bodies (MVBs).

Brandteknisk riskvärdering av Gamlestadsskolan

Detta är en brandteknisk riskvärdering av Gamlestadsskolan i kursen Brandteknisk riskvärdering på LTH. Gamlestadsskolan är en grund- och särskola för ungefär 650 elever belägen i Göteborg. Riskvärderingen går ut på att avgöra om säker utrymning i händelse av brand kan ske samt innefattar endast personsäkerheten och inte byggnader eller egendom. För att kunna utföra denna riskvärdering gjordes detThis report is a fire safety evaluation of the elementary school of Gamlestadsskolan in Gothenburg, Sweden. The evaluation was done to assess whether the fire safety for students, teachers and other staff is adequate. The evaluation was made in several steps and consists of a scenario analysis, choice of the two most critical scenarios to evaluate further, fire and evacuation simulations, risk eva

Purification Methods for Solid-State NMR Analysis of Influenza A M2[18-60]

Virusinfektioner har utan tvekan blivit det största hälsoproblemet i världen. I skrivande stund når antalet COVID-19 infektioner i världen upp emot 151 800 000 vilket gör att behovet av vacciner och antivirala läkemedel är viktigare nu än någonsin tidigare. Influensa A är ytligare ett virus som orsakar överdödlighet, trotts att många klarar sig lindrigt vid infektion. För att kunna förhindra ellerWith viral infections becoming an ever-increasing health problem in the world, the study of viral proteins is a cornerstone for understanding and preventing future pandemics. The following work shows the purification and structural characterization of the Influenza A M2 proton channel through solid-state NMR (ssNMR). Despite previously published structures of the M2 proton channel, the method of p

An integrated simulation-based method for considering weather effects on concrete work tasks’ productivity and concrete curing

This report presents an integrated simulation-based approach to study the on-site production of concrete frameworks by considering the multiple effects of weather on work task productivity and concrete curing process. The suggested approach enable to systematically study how different weather conditions and the use of climate-improved concrete in combination with different methods to shield concre

”A difficult and delicate process that is not simply a matter of the head, but more so of the heart” : Om försoning

Reconciliation research consists of two practices, one focusing on the emotional and healing aspects of the process and another that focus on the political and legal actions. Yeudith Auerbach created a theory, the reconciliation pyramid, which aims to manage both aspects. The purpose of this thesis is to apply Auerbach's theory to the reconciliation process in two empirical cases, the Rwandan

Conservation Efforts for Pied Tamarins (Saguinus bicolor) - Evaluating Ecological Corridors for Restoring the Forest Fragments of Urban Manaus, Brazil

Conservation efforts for the Pied Tamarin in urban Manaus, Brazil One of the Amazons most endangered species is the small New World primate, ´pied tamarin´ (Saguinus bicolor). The species only occurs in the vicinity of the Brazilian Amazonas state capital city Manaus, where greatly scattered and fragmented small patches of highly degraded forest remain. The on-going growth of Manaus urban area hOne of the Amazon´s most endangered species is the small New World primate, ´pied tamarin´ (Saguinus bicolor). The species only occurs in the vicinity of the Brazilian Amazonas state capital city Manaus, where greatly scattered and fragmented small patches of highly degraded forest remain. The on-going growth of Manaus urban area has created habitat fragments where the pied tamarins now try to per

Evaluation of a miR-125a mimic using an established Luciferase assay and working towards a new model-system to study RNAi in Escherichia coli

Det finns tre grundläggande nivåer vid vilken en cell kan reglera mängden av ett visst protein. Den första nivån är i vilken omfattning den kodande delen av en gen transkriberas från DNA till RNA. Den andra delen är i vilken omfattning detta RNA, även kallat messengerRNA (mRNA), translateras till ett färdigt protein. Den tredje och sista delen är i vilken utsträckning detta protein bryts ner. RNA-RNA interference (RNAi) plays a major role in regulation of gene expression in most eukaryotic organisms. On a basic level it is a protein complex named RNA induced silencing complex (RISC) that binds a RNA strand, a micro RNA (miRNA) or a small interfering RNA (siRNA), which guides it to its intended target, an mRNA. The RISC then disrupts translation of the bound mRNA, either by restricting it t

The barriers of circular public procurement for ICTs

Offentlig upphandling är en inköpsprocess av nyttjas av offentliga verksamheter såsom myndigheter och kommuner. Årligen spenderar Sverige ca 800 miljarder kronor via offentliga upphandlingar, vilket har en stor inverkan på miljön då dessa kontrakt ofta följer den linjära ekonomiska modellen, slit- och släng samhället. Begreppen cirkularitet och cirkulär ekonomi är relativt nya koncept som har de sThe EU procured for roughly 202000 MEUR (14% of the EU GDP) during 2021 in the public sector. The majority of these contracts are traditional, linear business model purchases. The EU has been developing several strategies, guidelines, and policies for sustainable purchasing, with Circular Public Procurement for a Circular Economy (CE) being one of them, but the implementation rate is low. Electron

The Role of Open-Innovation for Product Development: A Study of Swedish Biotechnology Small-Medium-Sized Enterprises in the Healthcare Sector

In the rapidly-evolving technological landscape of today, even established research and development (R&D) companies are struggling to keep pace with the demands of innovation. It creates difficulties for small-medium-sized enterprises (SMEs) with especially limited resources to maintain competitiveness within the market. This study argues that open innovation practices can provide a solution t

A comparison between HPGe- and NaI(Tl)-systems in finding lost point sources and optimisation of collecting parameters

Up to recently mobile gamma spectrometry has mostly been performed with NaI(Tl)-based detector systems. However lately the interest of using HPGe(High Purity Germanium)-based systems have increased and one has realised that the excellent energy resolution of HPGe-detectors, in combination with the possibility to manufacture larger crystals than before, is an advantage not only when performing in s

Automatic exposure control in CT an investigation between different manufacturers considering radiation dose and image quality

Background: Data from 1998 showed that CT represents about 10% of all the diagnostic X-ray examinations and almost 70% of the total radiation dose from medical diagnostic examinations in Sweden. Because of this there is a strong need to minimize the radiation dose and adapt the dose to each patient’s examination area and anatomy. Today practically all-modern CT systems are delivered with automatic

Dimensioning load flow scenarios for capacity analysis - A case study of the 135 kV grid in Southern Sweden

Society is undergoing a great transformation with regard to the climate crisis, where electrification plays a crucial role in decarbonizing. To meet the future energy demand, improving power grid utilization is essential. This thesis develops standardized methods to evaluate and identify key parameters in terms of impact and branch loading, and to determine the probability of load flow scenarios u

Towards Quantifying Veto Power with the LDMX HCal prototype

Vad kan stoppa oss från att hitta mörk materia med LDMX? När astronomer tittar på de största objekten i vårt universum ser de att stora strukturer, så som som galaxer och galaxkluster, inte rör sig som de förväntar sig. Det visar sig att det finnas en stor mängd extra materia som vi inte kan se. Denna osynliga materia kallar vi ’mörk materia’. Många teorier för vad mörk materia består av har lagtAccording to astronomical observations of galaxies and other large scale dynamics, the universe contains more mass than what is visible. This missing mass is called "dark matter" and have been a subject of study for physicists for decades. The Light Dark Matter eXperiment (LDMX) is a proposed experiment with the purpose to search for dark matter in a low mass range that not many experime

Klimatreducerande lösningar för en prefabricerad betongstomme

Då byggbranschen står för en femtedel av den svenska ekonomins totala årliga växthusgasutsläpp, har sektorn en avgörande roll i arbetet mot en hållbar utveckling. Klimatpolitiska mål och styrmedel har tagits fram i syfte att leda branschen mot den hållbara utvecklingen. Lagstadgade klimatdeklarationer och gränsvärden för byggnaders klimatpåverkan är styrmedel för Sveriges färdplan mot uppfyllandetThe construction industry is responsible for approximately 20% of Sweden’s annual greenhouse gas emissions and plays a key role in achieving national climate goals. As building operations become more energy efficient, emissions from the construction phase, particularly from concrete frameworks become increasingly significant. This thesis investigates emission reducing alternatives for a fully pref

Assessing the Impact of the European Union in Kosovo Conflict Resolution : Building States and Societies upon Tabula Rasa?

The international relations has been marked with the increased intra state ethnic conflicts which are able to cause huge humanitarian disasters and harbour instability and various threats for the international community. As a result, conflict resolution as a long term process combining social, economic and political levels and activities concerning structural change has been advocated in recent ye

Indonesian Literature vs New Order Orthodoxy. The Aftermath of 1965-1966.

Popular Abstract in Swedish Regimskiftet 1965-1966 i Indonesien åtföljdes av en massaker på kommunister och vänstersympatisörer, varvid uppskattningsvis 1/2 miljon människor fick sätta livet till. Ytterligare 100.000-tals personer internerades i över ett decennium, somliga så länge som 30 år utan att deras sak blev prövad i en rättegång. Andra blev summariskt avrättade. Så sent som på 1990 talet vStarting from Theodor Adorno´s assertion that art is negative knowledge of the real world, the book analyses Indonesian literature produced during the New Order which deal with the events of 1965-1966 and its consequences. A number of Indonesia´s best known authors have written on the subject. The central issue raised is the extent to which this literature has contributed to undermining and thereb

The Epistle of Jude : Its Text and Transmission

Popular Abstract in Swedish Avhandlingen behandlar det nytestamentliga Judasbrevets texthistoria. Monografin inleds med en översikt av textforskningen på de Katolska Breven i allmänhet och Judasbrevet i synnerhet, från 1800-talet och fram till nutid. Mot bakgrund av det tecknade forskningsläget beskriver så författaren studiens upplägg och syfte, samt antyder några av resultaten. Det handlar främsThis study treats the textual tradition of the Epistle of Jude. After an introductory survey of earlier text-critical research, the two main purposes of this investigation are formulated: to gather and to analyze the complete textual evidence of the Epistle of Jude. The first task, to gather the evidence, involves the collation of all Greek continuous text MSS of the Epistle of Jude. The evidence

Mönsteranalys av inomhusluft. Undersökning av luftkvaliteten i sjuka hus med flytspackelproblem

Den hälsomässiga effekten som rapporteras i samband med sjuka-hus syndromet (SBS), vars orsak är okänd, kan betraktas som ett mönster av icke specifika symptom såsom irritationer i ögon, näsa och mun, upplevelser av torra sletnhinnor och hud, hudrodnad, mental trötthet och upplevelse av svag men ihållande lukt. Aven exponeringar i inomhusluften kan beskrivas som ett mönster av en mängd olika ämnen

Gene×dietary pattern interactions in obesity: analysis of up to 68,317 adults of European ancestry.

Obesity is highly heritable. Genetic variants showing robust associations with obesity traits have been identified through genome-wide association studies. We investigated whether a composite score representing healthy diet modifies associations of these variants with obesity traits. 32 BMI- and 14 waist-hip ratio (WHR)-associated SNPs were genotyped and genetic risk scores (GRS) calculated in 18