Filtyp
Background: The contribution of smoking to rheumatoid arthritis (RA) is hypothesized to be mediated through formation of anti-citrullinated protein antibodies (ACPA). In RA, however, autoantibodies such as ACPA, rheumatoid factor (RF), and anti-carbamylated protein antibodies (anti-CarP) often occur together, and it is thus unclear whether smoking is specifically associated with some autoantibodie
Summary: Why do forest productivity and biomass decline with elevation? To address this question, research to date generally has focused on correlative approaches describing changes in woody growth and biomass with elevation. We present a novel, mechanistic approach to this question by quantifying the autotrophic carbon budget in 16 forest plots along a 3300 m elevation transect in Peru. Low growt
BACKGROUND: Recent outbreaks of poliomyelitis caused by vaccine-derived virus have raised concerns that vaccine-derived poliovirus may continue to circulate after eradication. In these outbreaks, the virus appears to have replicated for > or =2 years before detection. Early detection is critical for an effective response to these outbreaks. Although acute flaccid paralysis (AFP) surveillance will
Human immunodeficiency virus type 1-based lentivirus vectors containing the green fluorescent protein (GFP) gene were used to transduce murine Lin(-) c-kit(+) Sca1(+) primitive hematopoietic progenitor cells. Following transduction, the cells were plated into hematopoietic progenitor cell assays in methylcellulose and the colonies were scored for GFP positivity. After incubation for 20 h, lentivir
Climate change has the potential to affect the ecology and evolution of every species on Earth. Although the ecological consequences of climate change are increasingly well documented, the effects of climate on the key evolutionary process driving adaptation - natural selection - are largely unknown. We report that aspects of precipitation and potential evapotranspiration, along with the North Atl
The Paleoproterozoic Era witnessed crucial steps in the evolution of Earth's surface environments following the first appreciable rise of free atmospheric oxygen concentrations ∼2.3 to 2.1 Ga ago, and concomitant shallow ocean oxygenation. While most sedimentary successions deposited during this time interval have experienced thermal overprinting from burial diagenesis and metamorphism, the ca. 2.
Osteoarthritis (OA) constitutes a major and increasing burden on patients, health care systems and the broader society. It is estimated that around a quarter of the adult population is affected by OA in the knee and hip and that the prevalence of OA will increase over the coming decades largely due to aging and adverse life-style factors. Prevention and effective care are critical to manage the ch
Graft-versus-host disease (GVHD) is the major complication of allogeneic hematopoietic cell transplantation, a potentially curative therapy for hematologic diseases. It has long been thought that murine bone marrow-derived T cells do not mediate severe GVHD because of their quantity and/or phenotype. During the course of experiments testing the impact of housing temperatures on GVHD, we discovered
BACKGROUND: Protein S is an important regulatory protein of the coagulation cascade. The risk for venous thrombosis associated with protein S deficiency has been uncertain because all previous risk estimates used phenotypic evaluation alone, which can be ambiguous.OBJECTIVE: To quantitate the risk for thrombosis associated with a characterized protein S gene mutation that causes a Gly295-->Val sub
Plants make specialized bioactive metabolites to defend themselves against attackers. The conserved control mechanisms are based on transcriptional activation of the respective plant species-specific biosynthetic pathways by the phytohormone jasmonate. Knowledge of the transcription factors involved, particularly in terpenoid biosynthesis, remains fragmentary. By transcriptome analysis and functio
BACKGROUND: A mutation found in the BRCA1 or BRCA2 gene of a breast tumor could be either germline or somatically acquired. The prevalence of somatic BRCA1/2 mutations and the ratio between somatic and germline BRCA1/2 mutations in unselected breast cancer patients are currently unclear.PATIENTS AND METHODS: Paired normal and tumor DNA was analyzed for BRCA1/2 mutations by massively parallel seque
Genes encoding the DNA helicase TWINKLE (C10orf2) or the two subunits of mtDNA polymerase γ (POLγ) (POLG1 and POLG2) have a direct effect on the mitochondrial DNA replication machinery and were reported in many mitochondrial disorders. Friedreich's ataxia (FRDA) is the common cause of ataxia often associated with the expansion of a GAA repeat in intron 1 of the frataxin gene (FXN). Mitochondrial D
The best current model of breast cancer evolution suggests that most cancers arise from certain premalignant lesions. We have identified a common (34%) somatic mutation in the estrogen receptor (ER)-alpha gene in a series of 59 typical hyperplasias, a type of early premalignant breast lesion. The mutation, which affects the border of the hinge and hormone binding domains of ER-alpha, showed increa
Verksamhetsplan och resursfördelning 2022 Verksamhetsplan och resursfördelning 2022 Planeringsförutsättningar för 2023 och 2024 LUNDS UNIVERSITET | DNR STYR 2021/19 | BESLUT 2021-10-29 3 FÖREKOMMANDE FÖRKORTNINGAR EHL – Ekonomihögskolan, HT – Humanistiska och teologiska fakulteterna J – Juridiska fakulteten K – Konstnärliga fakulteten LTH – Lunds tekniska högskola M – Medicinska fakulteten N – Nat
Årshögtid Lunds universitet | 29 januari 2016 4 ÅRSHÖGTID 5ÅRSHÖGTID Program Årshögtid 29 januari 2016 Produktion: Akademiintendenturen vid Lunds universitet. Layout: Gunilla Albertén, Media-Tryck. Foto: sidan 1, 2 och 27: Kennet Ruona; sidan 7: Gunnar Menander. Upplaga: 600 ex. Tryck: Media-Tryck, Lund 2016 Procession Tyleman Susato: La Mourisque Lunds universitets brassband Tal av rektor Profess
https://www.lu.se/sites/www.lu.se/files/arshogtiden_-2016.pdf - 2026-10-13
Brist på handledning stressar Superchefer utvecklar goda ledare Donationsorgan går till spillo Tall i tanken LUNDS UNIVERSITETS MAGASIN | NR 5 | 2018 HÅLLBARARE BILKÖRNING MED GRÖN BENSIN 2 LUM NR 5 | 2018 Erik Hannerz och Peter Bengtsen stude- rar hur urban kreativitet, som till exempel graffiti, påverkar det offentliga rummet. LUM NR 5 | 2018 3 Banksys gatukonstmålningar har sedan länge flyttat
https://www.lu.se/sites/www.lu.se/files/lunds-universitets-magasin-5-2018.pdf - 2026-10-13
Skissernas nyinvigs Hemarbete utmanar hierarkier Forskare värnar om administratörer GENOM UNIVERSITETET UNDER 350 ÅR En tidsresa LUNDS UNIVERSITETS MAGASIN | NR 8 | 2016 2 LUM NR 8 | 2016 LUM NR 8 | 2016 3 – Relevansen för all den tid man lagt ner på sin avhandling ökar om man försöker nå ut i samhället med sin kunskap och sina resultat. I synnerhet med ett ämne som mitt som direkt berör skolan, s
https://www.lu.se/sites/www.lu.se/files/lunds-universitets-magasin-8-2016.pdf - 2026-10-13
