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Visions, or revelations, played an enormously important role in late medieval society. So much so that the question what constituted an authentic vision was debated at the highest ecclesiastical levels. Furthermore, the majority of visionaries in this period were women, and visions afforded them with unique opportunities to exercise their abilities in contexts otherwise almost exclusively reservedVisions, or revelations, played an enormously important role in late medieval society. So much so that the question what constituted an authentic vision was debated at the highest ecclesiastical levels. Furthermore, the majority of visionaries in this period were women, and visions afforded them with unique opportunities to exercise their abilities in contexts otherwise almost exclusively reserved

BACKGROUND: Multi-atlas segmentation, a popular technique implemented in the Automated Segmentation of Hippocampal Subfields (ASHS) software, utilizes multiple expert-labelled images ("atlases") to delineate medial temporal lobe substructures. This multi-atlas method is increasingly being employed in early Alzheimer's disease (AD) research, it is therefore becoming important to know how the constr

Approximately 70% of breast cancers express estrogen receptor α (ERα) and depend on this key transcriptional regulator for proliferation and differentiation. While patients with this disease can be treated with targeted antiendocrine agents, drug resistance remains a significant issue, with almost half of patients ultimately relapsing. Elucidating the mechanisms that control ERα function may furth

INTRODUCTION: Height, body mass index (BMI), and weight gain are associated with breast cancer risk in the general population. It is unclear whether these associations also exist for carriers of pathogenic variants in the BRCA1 or BRCA2 genes.PATIENTS AND METHODS: An international pooled cohort of 8091 BRCA1/2 variant carriers was used for retrospective and prospective analyses separately for prem

The new genus Kudratoviella for the former Caloplaca zeorina group having the highest level of bootstrap support in the phylogenetic tree of the Teloschistaceae, based on combined dataset of nrITS, 28S nrLSU DNA and 12S SSU mtDNA sequences, which does not belong to any other earlier proposed genera of the subfamily Xanthorioideae, is described. The genus Oceanoplaca Arup, Søchting et Bungartz founThe new genus Kudratoviella for the former Caloplaca zeorina group having the highest level of bootstrap support in the phylogenetic tree of the Teloschistaceae, based on combined dataset of nrITS, 28S nrLSU DNA and 12S SSU mtDNA sequences, which does not belong to any other earlier proposed genera of the subfamily Xanthorioideae, is described. The genus Oceanoplaca Arup, Søchting et Bungartz foun

Prosperous cities have constantly changed and their ability to adapt to contemporary commercial demands has always been rewarded, but this may no longer be the case. Delhi residents are now paying a high price for this endeavor with schools closed due to toxic air caused by high levels of carbon dioxide. Although previous urban transformations by drastic demolition had an insignificant climate imp

Prostate-specific antigen (PSA) screening for prostate cancer remains controversial because it increases overdiagnosis and overtreatment of clinically insignificant tumors. Accounting for genetic determinants of constitutive, non-cancer-related PSA variation has potential to improve screening utility. In this study, we discovered 128 genome-wide significant associations (P < 5 × 10 -8) in a multi

Civic integration is an essential part of contemporary migration control regimes. This thesis examines what happens when civic integration policy enters domestic courts, by focusing on how Sweden’s migration courts (which are part of the administrative courts) apply the income and housing requirements for family reunification.The thesis revolves around a common discussion in the legal literature,

Epigenetic silencing defends against LINE-1 (L1) retrotransposition in mammalian cells. However, the mechanisms that repress young L1 families and how L1 escapes to cause somatic genome mosaicism in the brain remain unclear. Here we report that a conserved Yin Yang 1 (YY1) transcription factor binding site mediates L1 promoter DNA methylation in pluripotent and differentiated cells. By analyzing 2

BACKGROUND AND AIMS: This study aimed to expand the European Prospective Investigation into Cancer and Nutrition (EPIC) nutrient database (ENDB) by adding amino acid (AA) values, using the U.S. nutrient database (USNDB). Additionally, we aimed to evaluate these new protein and AA intake estimates from the EPIC dietary questionnaires (DQ) and 24-h dietary recalls (24-HDR) using different matching p

Havsnivån stiger till följd av den globala uppvärmningen. Fastigheter kommer att drabbas av översvämningar och stora fastighetsvärden kommer att påverkas. Länsförsäkringar beslutade 2018 att sluta försäkra nybyggnation av bostäder inom områden som löper risk för översvämning där länsstyrelsen har avrått från byggnation. Flera kommuner planerar för skydd av befintlig bebyggelse, men examensarbe

Popular Abstract in Swedish Alla friska människor har 46 kromosomer, 23 av dessa härstammar från modern och 23 från fadern. Kromosomer är långa kedjor av nukleinsyror som innehåller den genetiska informationen (arvsanlagen) som behövs för att ett befruktat ägg skall kunna utvecklas till en individ bestående av miljontals celler med mycket specialiserade och avancerade uppgifter. Den här utvecklingThe cells in B cell development can be divided into several subgroups or fractions, e.g. early-pro-B-, pro-B, large-pre-B-, small-pre-B-, immature and mature B cells, where the stages reflect the maturity degree of the cells. This characterization is based on the expression of intracellular markers such as the recombination activating genes 1 and 2(Rag 1 and Rag 2), the terminal deoxynucleotidyl t

Deep brain stimulation (DBS) is associated with significant improvement of motor complications in patients with severe Parkinson's disease after some 6-12 months of treatment. Long-term results in a large number of patients have been reported only from a single study centre. We report 69 Parkinson's disease patients treated with bilateral DBS of the subthalamic nucleus (STN, n = 49) or globus pall

Objective: To describe anthropometric characteristics of participants of the European Prospective Investigation into Cancer and Nutrition (EPIC). Design: A cross-sectional analysis of baseline data of a European prospective cohort study. Subjects: This analysis includes study populations from 25 centres in nine European countries. The British populations comprised both a population-based and a 'he

Projectile fragmentation of a 750 MeV/nucleon U-238 beam was used to populate neutron-deficient nuclei around A similar to190. Isomeric states in Hg, Tl, Pb, Bi, and Po isotopes were identified and their lifetimes determined, with the ultimate aim of measuring their isomeric ratios to provide information on the spin population in such reactions.

Popular Abstract in Swedish Avhandlingen utgångspunkt tas från den senmesolitiska boplatsen vid Motala ström, Motala stad, Östergötland, Sverige. Problematiken som diskuteras i texten utgår från frågeställningarna vad som formade de materiella uttrycken under en 500-årig tidsperiod, 5500-5000 f.Kr, dokumenterade genom arkeologiska undersökningar. Texten i avhandlingen är i analysen strukturerad i This dissertation focuses on the Strandvägen site located in the town of Motala, Östergötland, Sweden. The problem concerns what shaped the material expressions on the site during 5500?5000 B.C. For reasons of text structure the space outside the settlement site (the home) is divided into the world, the district, and the neighbourhood. These spatial concepts are finally brought together in the syn

Popular Abstract in Swedish Forskarna inom Chicagoskolan var de första i ett akademiskt ramverk som systematiskt och etnografiskt satte gruppen och människan i centrum i en modern urban kontext. Det hade förekommit andra som skrivit om industrialism, modernism, urbanitet och de fattiga i slummen, men inte på ett lika systematiskt och genomträngande sätt som Chicagoskolan. Skolans strävan att föranThe main purpose of my thesis is to investigate how the Chicago School in urban sociology, that was active between 1915 and 1935, developed and why it produced so many classical monographs during a period of about ten to fifteen years. To outline the historical reasons for the School to develop I have chosen to view the historical context as a field with different actors. Another related and overa