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Popular Abstract in Swedish Alla friska människor har 46 kromosomer, 23 av dessa härstammar från modern och 23 från fadern. Kromosomer är långa kedjor av nukleinsyror som innehåller den genetiska informationen (arvsanlagen) som behövs för att ett befruktat ägg skall kunna utvecklas till en individ bestående av miljontals celler med mycket specialiserade och avancerade uppgifter. Den här utvecklingThe cells in B cell development can be divided into several subgroups or fractions, e.g. early-pro-B-, pro-B, large-pre-B-, small-pre-B-, immature and mature B cells, where the stages reflect the maturity degree of the cells. This characterization is based on the expression of intracellular markers such as the recombination activating genes 1 and 2(Rag 1 and Rag 2), the terminal deoxynucleotidyl t

Adherence by Helicobacter pylori increases the risk of gastric disease. Here, we report that more than 95% of strains that bind fucosylated blood group antigen bind A, B, and O antigens (generalists), whereas 60% of adherent South American Amerindian strains bind blood group O antigens best (specialists). This specialization coincides with the unique predominance of blood group O in these Amerindi

Popular Abstract in Swedish Avhandlingen utgångspunkt tas från den senmesolitiska boplatsen vid Motala ström, Motala stad, Östergötland, Sverige. Problematiken som diskuteras i texten utgår från frågeställningarna vad som formade de materiella uttrycken under en 500-årig tidsperiod, 5500-5000 f.Kr, dokumenterade genom arkeologiska undersökningar. Texten i avhandlingen är i analysen strukturerad i This dissertation focuses on the Strandvägen site located in the town of Motala, Östergötland, Sweden. The problem concerns what shaped the material expressions on the site during 5500?5000 B.C. For reasons of text structure the space outside the settlement site (the home) is divided into the world, the district, and the neighbourhood. These spatial concepts are finally brought together in the syn

A systematic study of the population probabilities of nanosecond and microsecond isomers produced following the projectile fragmentation of U-238 at 750 MeV/nucleon has been undertaken at the SIS/FRS facility at GSI. Approximately 15 isomeric states in neutron-deficient nuclei around A similar to 190 were identified and the corresponding. isomeric ratios determined. The results are compared with a

Popular Abstract in Swedish Forskarna inom Chicagoskolan var de första i ett akademiskt ramverk som systematiskt och etnografiskt satte gruppen och människan i centrum i en modern urban kontext. Det hade förekommit andra som skrivit om industrialism, modernism, urbanitet och de fattiga i slummen, men inte på ett lika systematiskt och genomträngande sätt som Chicagoskolan. Skolans strävan att föranThe main purpose of my thesis is to investigate how the Chicago School in urban sociology, that was active between 1915 and 1935, developed and why it produced so many classical monographs during a period of about ten to fifteen years. To outline the historical reasons for the School to develop I have chosen to view the historical context as a field with different actors. Another related and overa

Gamma ray spectroscopy of neutron deficient nuclei close to the doubly magic nucleus Sn-100 has been performed using a heavy-ion reaction and the NORDBALL Ge-detector array. Evaporation residues were identified by means of charged particle and neutron detection. Transitions in 31 different evaporation residues were identified. New results on Cd-102 are presented.

Popular Abstract in Swedish Syftet med den här studien är att undersöka utvecklingen av språkfärdigheten i skriftlig produktion av franska som främmande språk. Vi har följt 5 inlärares produktion av franska i en 30 månader lång longitudinell studie. För att kunna utvärdera färdigheten har vi använt oss av parametrarna flyt, komplexitet och korrekthet. Flyt och komplexitet har utvärderats med hjälpThe aim of this study is to examine the development of linguistic proficiency in written production of second-language French. In a longitudinal study of 30 months, we follow the written production of 5 guided learners of French as a second language. In order to apprehend proficiency we use the conventional parameters fluency, complexity and accuracy. The fluency and complexity are apprehended by

High-spin states in Lu-165 were populated in the La-139(Si-30, 4n) reaction at a beam energy of 152 MeV and gamma-ray coincidences were measured with the EUROBALL spectrometer array. Nine new rotational bands were discovered, known band structures were considerably extended and many inter-band transitions were found. Structures with normal deformation coexist with bands associated with the strongl

The magnitude of the Coulomb mixing parameter delta (l)(IM) has been experimentally deduced, for the first time, for the B decay of Rb-74. Th, estimated magnitude is derived from the feeding of the non-analog first excited 0(+) state in Kr-74. The inferred upper Limit of 0.07% is small compared to theoretical predictions. The half-life was measured to be 64.90(9) ms. (C) 2001 Published by Elsevier

Excited states of Ga-65 and Ga-67 nuclei were populated through the C-12(Ni-58,alpha p) and C-12(Ni-58,3p) reactions, respectively, and investigated by in-beam gamma-ray spectroscopic methods. The NORDBALL array equipped with a charged particle ball and 11 neutron detectors was used to detect the evaporated particles and gamma rays. The level schemes of Ga-6.5.67 were constructed On the basis of g

To determine the frequency of each American College of Rheumatology (ACR) criterion met at time of enrollment, and the increase in each of the criteria over 5 years.

NF-κB is constitutively activated in chronic lymphocytic leukemia (CLL); however, the implicated molecular mechanisms remain largely unknown. Thus, we performed targeted deep sequencing of 18 core complex genes within the NF-κB pathway in a discovery and validation CLL cohort totaling 315 cases. The most frequently mutated gene was NFKBIE (21/315 cases; 7%), which encodes IκBε, a negative regulato

Susceptibility to lung cancer may in part be attributable to inter-individual variability in metabolic activation or detoxification of tobacco carcinogens. The glutathione S-transferase M1 (GSTM1) genetic polymorphism has been extensively studied in this context; two recent meta-analyses of case-control studies suggested an association between GSTM1 deletion and lung cancer. At least 15 studies ha

Objective. To examine, in an inception cohort of systemic lupus erythematosus (SLE) patients, the association between neuropsychiatric (NP) events and anti-ribosomal P (anti-P), antiphospholipid (lupus anticoagulant [LAC], anticardiolipin), anti-beta 2-glycoprotein I, and anti-NR2 glutamate receptor antibodies. Methods. NP events were identified using the American College of Rheumatology case defi

The ELDCARE study aims to investigate, at the ecological level, the relationships between socio-economic variables and cancer survival in patients aged 65 years and over. Survival data for patients diagnosed during the period 1985-1989 and followed up to 1994 were provided by 43 European Cancer Registries in 16 countries participating in the EUROCARE 2 project. Relative survival was computed by Ha

IL-5 is a Th2 cytokine which activates eosinophils and is suggested to have an atheroprotective role. Genetic variants in the IL5 locus have been associated with increased risk of CAD and ischemic stroke. In this study we aimed to identify genetic variants associated with IL-5 concentrations and apply a Mendelian randomisation approach to assess IL-5 levels for causal effect on intima-media thickn

To assess the role of CHCHD2 variants in patients with Parkinson disease (PD) and Lewy body disease (LBD) in Caucasian populations.

Context: Polymorphisms in genes involved in regulation, biosynthesis, metabolism, and actions of testicular sex hormones may influence hormone balance and phenotype of aging men. Objective: We investigated the relationships between polymorphisms in genes related to pituitary-testicular endocrine function and health status. Design and Setting: Using cross-sectional baseline data, we conducted a mul

Popular Abstract in Swedish Vi går mot ett mer och mer energikrävande samhälle. För att klara ett ökande behov av energi med de begränsande naturresurser som finns på jorden, har ett forskningsprojekt, som denna avhandling är en del av, som mål att utveckla artificiell fotosyntes. Den naturliga fotosyntesen använder sig av solljus för att omvandla koldioxid och vatten till energirika produkter såsThe work in thesis aims for artificial photosyntesis, which could and will mimic natural photosynthesis, the process that uses light to create energy rich compounds from H2O and CO2. Water is oxidized in Photosystem II (PSII) by the Water Oxidizing Complex (WOC), which is a catalytic site on the lumenal side of the thylakoid membrane. The chlorophyll complex P680 absorbs light and electrons are tr