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The construction industry is affected by several ongoing crises, derived from e.g. the climate emergency and geopolitical challenges. Thus, new thinking and novel business models are much needed. The major role of the construction industry in the climate energy and resource depletion calls for sustainable and circular business models specifically. Consequently, this study aims to develop a sustain
The extensive genetic diversity of HIV-1 represents a major challenge to public health interventions, treatment, and successful vaccine design. This challenge is particularly pronounced in the Middle East and North Africa (MENA) region, where limited data among other barriers preclude the accurate characterization of HIV-1 genetic diversity. The objective of this review was to analyze studies cond
We present the discovery and characterization of two warm mini-Neptunes transiting the K3V star TOI-815 in a K–M binary system. Analysis of its spectra and rotation period reveal the star to be young, with an age of 200+−400200 Myr. TOI-815b has a 11.2-day period and a radius of 2.94 ± 0.05 R+ with transits observed by TESS, CHEOPS, ASTEP, and LCOGT. The outer planet, TOI-815c, has a radius of 2.6
OBJECTIVE: Infective native aneurysms of the femoropopliteal arteries (INA-FPs) are rare and mostly reported in intravenous drug users (IVDU). This study aimed to summarize all cases of INA-FPs presented in the literature, to describe patient characteristics, microbiology, treatments and outcomes, and compare IVDU with non-IVDU patients.METHODS: A systematic search of PubMed, ScienceDirect, Embase
Introduction: Malaria remains a persistent challenge in global health, disproportionately affecting populations in endemic regions (eg, sub-Saharan Africa). Despite decades of international collaborative efforts, malaria continues to claim hundreds of thousands of lives each year, with young children and pregnant women enduring the heaviest burden. This concise review aimed to provide an up-to-dat
Bouchra Khalili occupies three theater stages, offering the present a sensitive echo of hidden memories and forgotten stories.With her project Asterisms (Fig. 1 to 3), Bouchra Khalili, visual artist invited to the 2025 edition of the Festival d’Automne, successively invests three theater stages to explore the links between the representation of buried histories, performance, and moving images. Dra
We present new observations from CHEOPS (CHaracterising ExOPlanet Satellite) and TESS (Transiting Exoplanet Survey Satellite) to clarify the architecture of the planetary system hosted by the old Galactic thick disc star TOI-561. Our global analysis, which also includes previously published photometric and radial velocity data, incontrovertibly proves that TOI-561 is hosting at least four transiti
Southern Kazakhstan, particularly the Zhambyl Region, is facing increasing groundwater stress due to climate change, degradation of irrigation infrastructure, and unsustainable water use. Despite substantial renewable groundwater reserves (8.33 km3/year), irrigation still relies on ephemeral surface flow. This study delineates priority zones for Managed Aquifer Recharge (MAR) using a GIS-based Mul
Background: Neuroimaging with magnetic resonance imaging (MRI) may assist clinicians in evaluating brain injury and optimising care in comatose adults resuscitated after out-of-hospital cardiac arrest (OHCA). However, contemporary international data on its use are lacking. Aim: The primary aim was to compare the patient characteristics, early postresuscitation care, and neurological outcomes of pa
Background Primary ciliary dyskinesia (PCD) represents a group of rare hereditary disorders characterised by deficient ciliary airway clearance that can be associated with laterality defects. We aimed to describe the underlying gene defects, geographical differences in genotypes and their relationship to diagnostic findings and clinical phenotypes. Methods Genetic variants and clinical findings (a
Objectives: Posttransplant infections may lead to dire consequences in immunocompromised organ recipients. Oral foci of infection are therefore often eliminated prior to solid organ transplantation to reduce posttransplant morbidity. However, despite increasing numbers of organ transplantations the necessity of pretransplant dental treatment and its effect on transplant outcome remains uncertain.
Background: High-dose haemodiafiltration has been shown, in a randomised clinical trial, to result in a 23% lower risk of mortality for patients with kidney failure when compared with conventional high-flux haemodialysis. Nevertheless, whether treatment effects differ across subgroups, whether a dose–response relationship with convection volume exists, and the effects on cause-specific mortality r
Background: Beta-cell monogenic forms of diabetes have strong support for precision medicine. We systematically analyzed evidence for precision treatments for GCK-related hyperglycemia, HNF1A-, HNF4A- and HNF1B-diabetes, and mitochondrial diabetes (MD) due to m.3243 A > G variant, 6q24-transient neonatal diabetes mellitus (TND) and SLC19A2-diabetes. Methods: The search of PubMed, MEDLINE, and Emba
Context. Among the thousands of exoplanets discovered to date, approximately a few hundred gas giants on short-period orbits are classified as 'lonely'and only a few are in a multi-planet system with a smaller companion on a close orbit. The processes that formed multi-planet systems hosting gas giants on close orbits are poorly understood, and only a few examples of this kind of system have been
Context. The TOI-178 system consists of a nearby, late-K-dwarf with six transiting planets in the super-Earth to mini-Neptune regime, with radii ranging from ∼1.1 to 2.9 R⊕ and orbital periods between 1.9 and 20.7 days. All the planets, but the innermost one, form a chain of Laplace resonances. The fine-tuning and fragility of such orbital configurations ensure that no significant scattering or co
Multiplanetary systems spanning the radius valley are ideal testing grounds for exploring the different proposed explanations for the observed bimodality in the radius distribution of close-in exoplanets. One such system is HIP 29442 (TOI-469), an evolved K0V star hosting two super-Earths and one sub-Neptune. We observed HIP 29442 with CHEOPS for a total of 9.6 days, which we modelled jointly with
BACKGROUND: While the associations between pediatric non-obese metabolic dysfunction-associated fatty liver disease (MAFLD) and multiple diagnostic biomarkers are well-established, the role of a broader range of blood-based, urine-based, and body composition-based biomarkers for monitoring MAFLD are needed.METHODS: A pediatric cohort was established in Wuxi, China. We measured body composition bio
Context. Occultations are windows of opportunity to indirectly peek into the dayside atmosphere of exoplanets. High-precision transit events provide information on the spin-orbit alignment of exoplanets around fast-rotating hosts. Aims. We aim to precisely measure the planetary radius and geometric albedo of the ultra-hot Jupiter (UHJ) KELT-20 b along with the spin-orbit alignment of the system. M
Additive manufacturing creates surfaces with random roughness, impacting heat transfer and pressure loss differently than traditional sand–grain roughness. Further research is needed to understand these effects. We conducted high-fidelity heat transfer simulations over threedimensional additive manufactured surfaces with varying roughness heights and skewness. Based on an additive manufactured Inc
