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Background/Objectives: The stimulator of interferon genes (STING) pathway plays a central role in innate immune signaling and represents an attractive therapeutic target for cancer immunotherapy. Amidobenzimidazole (ABZI) derivatives have emerged as promising non-nucleotide STING agonists with improved drug-like properties compared to cyclic dinucleotides. However, current ABZI compounds still exh
BackgroundTimely discharge of patients who are clinically ready to be discharged from hospitals to the next point of care is a common health system challenge. Ensuring safe and effective discharge holds new urgency, given the backlogs and increased waiting times for inpatient services in many countries after the COVID-19 pandemic.ObjectiveThe study aimed to identify policy options for addressing d
Understanding the properties of hierarchical materials such as wood requires combining information representing different length scales. Scanning wide-angle X-ray scattering (WAXS) connects the nanoscale cell wall structure to the scale of the annual growth rings, as demonstrated here by studying radially cut slices of mature softwood (Scots pine and Norway spruce), including the bark. WAXS offers
Purpose: To assess perceived overall knowledge in geriatric medicine and perceived educational needs in key geriatric topics and skills of health and social care professionals working within the WHO Region Europe. Methods: The sample of this cross-sectional survey was not designed to be nationally representative. We analysed the responses of 5425 professionals who completed a multilingual multinat
Cerebrovascular reactivity (CVR) is increasingly recognized as a valuable clinical biomarker, making accurate, and reliable quantification essential, particularly in the absence of a gold-standard reference. However, both the acquisition and processing of CVR data are influenced by numerous methodological factors, including imaging technique, sequence parameters, vascular paradigm, and data proces
Ätstört beteende (DE) och icke-suicidalt självskadebeteende (NSSI) förekommer ofta samtidigt under ungdomsåren och delar flera riskfaktorer, men deras longitudinella utveckling är fortfarande bristfälligt kartlagd. Denna studie undersöker prevalens, stabilitet och psykologiska prediktorer för upprepat NSSI och risk för DE från ungdomsåren till ung vuxenålder. Ett urval (N = 471) besvarade självskaDisordered eating (DE) and non-suicidal self-injury (NSSI) frequently co-occur during adolescence and share multiple risk factors, yet their longitudinal development remains poorly understood. This study examined the prevalence, stability, and psychological predictors of repetitive NSSI and risk of DE from adolescence to young adulthood. A community sample (N = 471) completed self-report asse
This explorative case study examines librarians’ perceptions and practices regarding environmental sustainability at Malmö University library. More specifically the study addresses which conditions and challenges that underlie these practices, with a core emphasis on the librarians’ perceptions regarding the role of academic libraries in the sustainable shift in Swedish society. Analytically the s
This is a master’s thesis about reading promotion. The purpose of this study is to examine and increase knowledge about reading promotion in a school context. The example used is the project “Free Reading”, implemented by third year students at a high school in southern Sweden. “Free Reading” requires the students to read for 15 minutes at the start of every English lesson, in a book of their own
This thesis uses critical discourse analysis as both theory and method to examine how Legimus and its users are constructed in the Swedish public debate in the context of higher education. Drawing on critical disability studies and crip theory, the thesis aims to highlight the norms about ability and disability that these constructions legitimate and reproduce. The empirical material for this thes
Book displays in public libraries engage a broad range of users and shape patterns of borrowing and reading. They therefore constitute an important means through which libraries can express institutional values and promote their collections. The aim of this thesis is to advance knowledge of how book selection for display is conducted in public libraries. The study draws on observations in four lib
This study has highlighted academic librarians’ own perspectives and experiences of their work with accessible course literature for students with reading disabilities. The study has addressed how academic librarians described their work, which working conditions are central, and how the work is shaped by institutional and material changes. Using a practice-theoretical framework with a neoinst
This thesis investigates how Swedish men aged 45-60 describe their relationship to clothing, fashion and sustainable consumption, and how these practices are negotiated in relation to masculinity. Addressing a research gap on middle-aged men’s clothing practices, the study is based on ten qualitative semistructured interviews with men from different social and professional backgrounds. The analysi
This bachelor’s thesis investigates the role of the dress in three different romcom movies from the 1990s and 2000s. The chosen dresses for this analysis are the colorful mini-dress from 13 going on 30 (2004), the yellow gown from How to Lose A Guy in 10 Days (2003) and the purple-blue ballgown from 10 Things I Hate About You (1999). This thesis uses a semiotic analysis by Roland Barthes to study
This thesis has through a comparative analysis, of a preindustrial clothing culture and a postindustrial clothing culture, researched if it is possible to implement a preindustrial clothing usage in todays society, in order to create a more sustainable future in fashion. This was done through an analysis and comparison of wardrobe studies from both periods, with the usage of three terms and theori
This bachelor thesis aims to examine how real observers relate to the constructions of implicit beholders in three photographs from Madonna´s 1992 photobook, Sex. Through the use of a mixed method study composed of picture analysis and a focus group study, implementing a theoretical framework consisting of Wolfgang Kemps theory of the implicit beholder, Susan Sontag´s theories about photography an
This thesis explores cultural memory and collective identity in trip-hop music. First, I question what it was about Bristol’s history and demography that created such a highly interesting and unusual music scene. To examine how music carries cultural memory, an investigation of significant Bristol artists like Massive Attack and Tricky is undertaken. Expanding the scope, I compare these genres to
Magical realism and weird fiction are two genres that have become increasingly discussed in contemporary literary studies. However, previous research has largely focused on defining the characteristics of these genres, rather than on the specific readerly effects produced by their shared use of supernatural or impossible elements. I argue that it is not the presence of such elements alone that det
This thesis examines how American Author Jack London’s dystopian novel The Iron Heel (1908) depicts freedom as limited and unattainable under the conditions of concentrated economic power from an oligarchy. While previous discourse on The Iron Heel has focused on the intentions behind the creation of the novel, seeing it as either a work of protest, propaganda, or a way to endorse a Marxist ideolo
To tackle the social inequalities in how disasters unfold, organisations working in Disaster Risk Reduction and Management (DRRM) have increasingly adopted socially inclusive approaches. With a similar aim of reducing disaster impacts, Anticipatory Action (AA) has emerged as a practical method to prevent losses and damage through forecasts, pre-agreed funding, and early action. However, a gap rema
