Background. Myocardial infarction (MI) remains the leading cause of death worldwide, despite several advances in acute coronary care during the last decades. This thesis assessed different risk stratification tools and evaluated interventional and pharmacological treatment strategies in high-risk patients with MI. Methods. This work comprises four studies. The first and the fourth study extracted

Biofuels from vegetable oils or animal fats are considered to be more sustainable than petroleum-derived diesel fuel. In this study, we have assessed the effect of hydrogenated vegetable oil (HVO) exhaust on levels of DNA damage in peripheral blood mononuclear cells (PBMCs) as primary outcome, and oxidative stress and inflammation as mediators of genotoxicity. In a randomized cross-over study, hea

We show that a recent spectral flow approach proposed by Berkolaiko–Cox–Marzuola for analyzing the nodal deficiency of the nodal partition associated to an eigenfunction can be extended to more general partitions. To be more precise, we work with spectral equipartitions that satisfy a pair compatible condition. Nodal partitions and spectral minimal partitions are examples of such partitions. Along

Background and purpose: Up-to-date population-based information about long-term survival, causes of death and recurrence after stroke is needed. Methods: Four hundred consecutive individuals in a population-based cohort of first-ever stroke between 2015 and 2016 in Lund, Sweden, were followed up to 3 years regarding (i) survival (Swedish Population Register); (ii) causes of death (Swedish Causes o

Background: The SIOP-Renal Tumor Study Group (RTSG) does not advocate invasive procedures to determine histology before the start of therapy. This may induce misdiagnosis-based treatment initiation, but only for a relatively small percentage of approximately 10% of non-Wilms tumors (non-WTs). MRI could be useful for reducing misdiagnosis, but there is no global consensus on differentiating charact

Academia, as many other sectors, has faced wide-ranging disruptions due to COVID-19, with teaching and research activity conducted entirely online in many countries. Before the pandemic grounded travel, academics were often hypermobile, some traveling more than 150,000 kilometers per year for conferences, board meetings, collaborations, fieldwork,seminars, and lectures. It is no surprise then that

This paper discusses methods to test the performance of the adaptation layer in a self-adaptive system. The problem is notoriously hard, due to the high degree of uncertainty and variability inherent in an adaptive software application. In particular, providing any type of formal guarantee for this problem is extremely difficult. In this paper we propose the use of a rigorous probabilistic approac

Objective: To assess which structural abnormalities on knee MRI are associated with development of osteophytes in middle-aged subjects without radiographic knee osteoarthritis. Design: We included subjects from the Osteoarthritis Initiative, aged 40–55 years, Kellgren & Lawrence grade 0 in both knees, and knee MRIs from both knees available at baseline, 24, 48 and 72 months. Structural exposur

The high cycle fatigue behaviour of autoclave-cured carbon fibre-reinforced polymer (CFRP) composite gears is investigated. The CFRP gears were milled from a composite plate and tested in mesh with a steel drive gear under five torque loads ranging between 0.4 and 0.8 Nm in unlubricated conditions. A detailed gear damage analysis is conducted by employing scanning electron microscopy and high-reso

This special issue follows on from a special call for contributions tothe ECER 2016 conference in Dublin on the need to rethink andreconceptualise internationalisation in higher education (HE). Thepapers in this special issue contribute to a critically reflectiveinterdisciplinary discussion on the phenomena ofinternationalisation in terms of the evolution of the structures,systems, and functions o

The purpose of this thesis is to add an astronomical component to the history and evolution of Earth by reconstructing the micrometeorite flux to Earth at different time intervals during the Phanerozoic Eon, using sediment-dispersed extraterrestrial spinel group minerals as a proxy. Chromite and chrome spinel are common refractory members of the spinel group, occurring in both extraterrestrial and