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Numerical investigation of railway subgrade stiffening : Critical speed and free-field vibrations
For a train speed close to the speed of elastic waves in the soil, often referred to as “critical speed”, largely elevated vibration responses occur. This can be a practical problem for soft soil sites, where the phenomenon may cause excessive vibrations in the track and also at distances far from the track. To ensure the running safety of the train, the long-term quality of the track and to reduc
Luminescence characteristics of Scandinavian quartz, their connection to bedrock provenance and influence on dating results
The success of optically stimulated luminescence (OSL) dating relies to a large extent on suitable characteristics of the analysed mineral, in this case quartz. Previous OSL dating of Quaternary sediments in Scandinavia has shown that quartz characteristics vary widely across the region, resulting in dating studies with varied success. The aim of this study is to provide an overview of quartz lumi
Myocardial infarction in ANCA-associated vasculitis- a population-based cohort-study
Antipsychotic Use During Pregnancy and Risk for Gestational Diabetes : A National Register-Based Cohort Study in Sweden
Objective: We aimed to study whether antipsychotic use during pregnancy is associated with gestational diabetes. Methods: This was a Swedish national register‐based cohort study on the Medical Birth Register and the Prescribed Drug Register including all 1,307,487 singleton births between July 2006 and December 2017. Antipsychotics were divided into first-generation antipsychotics (n = 728), high-
Experimental study on combustion and flow resistance characteristics of an afterburner with air-cooled bluff-body flameholder
In the afterburner assembled with an air-cooled bluff-body flameholder, cooling air is directly injected into the recirculation zone behind the bluff-body, which can reduce the local temperature and increase the oxygen concentration of the gas mixture in the wake of the bluff-body, thereby affecting the total pressure loss and combustion characteristics. To better understand the flow and combustio
Epidemiology and Clinical Characteristics of Adult-Onset IgA Vasculitis in Southern Sweden
Evaluation of Antibiotic-Based Selection Methods for Camelina sativa Stable Transformants
Camelina sativa (Camelina) is an oilseed crop that in recent years has gained importance due to its closeness to the plant model organism Arabidopsis thaliana (Arabidopsis), its low agronomical requirements, and the ability to grow under temperate conditions. To explore all the agronomical and biotechnological possibilities of this crop, it is important to evaluate the usability of the molecular p
No evidence that sun exposure can decrease the risk of vasculitis
Practice-near school research in Sweden : tendencies and teachers’ roles
The Education Act from 2010 states that education in Sweden ought to be based on scientific knowledge and proven experience. The aim of this study is to explore practice-near school research published by Swedish researchers in the wake of the Education Act with the focus on the participation of teachers in research. As a background, the international and national roots of practice-near school rese
FAIRVASC: A semantic web approach to rare disease registry integration
Effects of the host defense peptide LL-37 on human cells : Immunomodulation and cytotoxicity
The human host defense peptide LL-37 has an essential role in the first line of defense against invading pathogens. This cathelicidin is mainly produced by immune cells and epithelial cells aligning the mucosal areas and is normally upregulated upon infection and inflammation. LL-37 displays direct antimicrobial activity against a variety of pathogens, but also modulates the immune responses by ac
FAIRVASC: A semantic web approach to rare disease registry integration
Rare disease data is often fragmented within multiple heterogeneous siloed regional disease registries, each containing a small number of cases. These data are particularly sensitive, as low subject counts make the identification of patients more likely, meaning registries are not inclined to share subject level data outside their registries. At the same time access to multiple rare disease datase
Cosmetic preservative labeling in Philippine products in accordance with Philippine regulations
Background: Preservatives are usually added to a wide array of consumer products to prevent growth of microbes and to prevent product destabilization and degradation. However, many of these preservatives are common skin sensitizers and may cause allergic contact dermatitis. The amount of preservatives may vary per country or region according to their respective legislation and may be reported in d
A Conceptual Framework for Understanding the Purpose of Change Initiatives
This paper develops a conceptual framework for understanding how organizations create an accepted purpose for organizational change initiatives related to business processes. The framework is based on a longitudinal study related to an Action Research project and the ‘higher level learning’ from using a performance measurement system for change initiatives. Over more than four years, we followed a
Dual SGLT1/SGLT2 inhibitor phlorizin reduces glucose transport in experimental peritoneal dialysis
Introduction: Glucose absorption during peritoneal dialysis (PD) is commonly assumed to occur via paracellular pathways. We recently showed that SGLT2 inhibition did not reduce glucose absorption in experimental PD, but the potential role of glucose transport into cells is still unclear. Here we sought to elucidate the effects of phlorizin, a non-selective competitive inhibitor of sodium glucose c
Antibiotic use in Australian and Swedish primary care : a cross-country comparison
Objective: Antimicrobial resistance is a growing worldwide problem and is considered to be one of the biggest threats to global health by the World Health Organization. Insights into the determinants of antibiotic prescribing may be gained by comparing the antibiotic usage patterns of Australia and Sweden. Design: Publicly available data on dispensed use of antibiotics in Australia and Sweden betw
Simulation of volumetric breast densities for virtual clinical trials
Risk factors and outcomes for patients with pancreatic cancer undergoing surgical exploration without resection due to metastatic disease : A national cohort study
Background: Unresectable disease is sometimes diagnosed during surgery in patients with pancreatic ductal adenocarcinoma (PDAC). This study aimed to identify preoperative risk factors for metastatic disease diagnosed at surgical exploration and to investigate and compare survival in resected and non-resected patients. Methods: Patients were identified from the Swedish National Pancreatic and Peria
Effect of a Smoking and Alcohol Cessation Intervention Initiated Shortly Before Radical Cystectomy—the STOP-OP Study : A Randomised Clinical Trial
Background: Evidence concerning the reduction of postoperative complications due to smoking and alcohol drinking in patients undergoing radical cystectomy is incomplete. Objective: To evaluate the efficacy of a 6-wk smoking and/or alcohol cessation intervention, initiated shortly before surgery and continued until 4 wk after, in reducing complications. Design, setting, and participants: Between 20