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Maternal smoking during pregnancy and daughters' risk of gestational diabetes and obesity.

AIMS/HYPOTHESIS: The primary aim of the study was to investigate the risk of developing gestational diabetes in women who were exposed to tobacco smoke in utero. Secondary aims were to assess the risk of obesity and non-gestational diabetes. METHODS: Data were retrieved from the Medical Birth Register of Sweden for women who were born in 1982 (when smoking data were first registered) or later and

Discourses of counter-Islamic-threat mobilization in post 9/11 documentaries

This article critically studies documentaries focusing on the "Islamic terrorist threat", produced in the US and in Western Europe. The particular films relate to the discourses of the growing far right political movements in liberal democracies. The article analyzes the communicational tactics deployed by the filmmakers for counter-terrorist mobilization of "Westerners". The films' producers obje

Aberrant recombination and repair during immunoglobulin class switching in BRCA1-deficient human B cells.

Breast cancer type 1 susceptibility protein (BRCA1) has a multitude of functions that contribute to genome integrity and tumor suppression. Its participation in the repair of DNA double-strand breaks (DSBs) during homologous recombination (HR) is well recognized, whereas its involvement in the second major DSB repair pathway, nonhomologous end-joining (NHEJ), remains controversial. Here we have st

Gendering Al-Nakba : Elderly Palestinian Refugees' Stories and Silences about Dying Children

This article builds on the life-stories of elderly Palestinian refugees, collected in the West Bank in 2003-2004. It discusses accounts about flight in 1948 (i.e. al-Nakba) and pays particular interest to stories as well as silences about dying children. The article argues that men and women remembered their flight differently and that the gendered experiences of flight influenced understandings o

Multispectral guided fluorescence diffuse optical tomography using upconverting nanoparticles

We report on improved image detectability for fluorescence diffuse optical tomography using upconverting nanoparticles doped with rare-earth elements. Core-shell NaYF4 : Yb3+/Er3+ @ NaYF4 upconverting nanoparticles were synthesized through a stoichiometric method. The Yb3+/Er3+ sensitizer-activator pair yielded two anti-Stokes shifted fluorescence emission bands at 540 nm and 660 nm, here used to

Measurement of the W -> lv and Z/gamma* -> ll production cross sections in proton-proton collisions at root s=7 TeV with the ATLAS detector

First measurements of the W -> lv and Z/gamma* -> ll (l = e; mu) production cross sections in proton-proton collisions at root s = 7 TeV are presented using data recorded by the ATLAS experiment at the LHC. The results are based on 2250 W -> lv and 179 Z/gamma* -> ll candidate events selected from a data set corresponding to an integrated luminosity of approximately 320 nb(-1). The measured total

Faceting, composition and crystal phase evolution in III-V antimonide nanowire heterostructures revealed by combining microscopy techniques

III-V antimonide nanowires are among the most interesting semiconductors for transport physics, nanoelectronics and long-wavelength optoelectronic devices due to their optimal material properties. In order to investigate their complex crystal structure evolution, faceting and composition, we report a combined scanning electron microscopy (SEM), transmission electron microscopy (TEM), and scanning

Increased plasma levels of the soluble Mer tyrosine kinase receptor in systemic lupus erythematosus relate to disease activity and nephritis

Introduction: Mer and Tyro3 are receptor tyrosine kinases important for the phagocytosis of apoptotic cells. Together with Axl, they constitute the TAM receptor family. These receptors can be shed from the cell membrane and their soluble extracellular regions can be found in plasma. The objective of this study was to elucidate whether the plasma levels of soluble Mer (sMer) and Tyro3 (sTyro3) were

The polygenic nature of inhibitors in hemophilia A: results from the Hemophilia Inhibitor Genetics Study (HIGS) Combined Cohort.

Studies of determinants of development of inhibitory antibodies to factor VIII in people with hemophilia A indicate a complex process involving multiple factors. The Hemophilia Inhibitor Genetics Study Combined Cohort was formed to extend understanding of the genetic background of risk. The study group contains 833 subjects from three independent cohorts: brother pairs and singletons with and with

Haemophilus influenzae: recent advances in the understanding of molecular pathogenesis and polymicrobial infections.

Non-typeable Haemophilus influenzae (NTHi) is a human-specific mucosal pathogen and one of the most common causes of bacterial infections in children and patients with chronic obstructive pulmonary disease. It is also frequently found in polymicrobial superinfections. Great strides have recently been made in the understanding of the molecular mechanisms underlying NTHi pathogenesis.

The Tyrosine Kinase Inhibitors Imatinib and Dasatinib Reduce Myeloid Suppressor Cells and Release Effector Lymphocyte Responses

Immune escape mechanisms promote tumor progression and are hurdles of cancer immunotherapy. Removing immunosuppressive cells before treatment can enhance efficacy. Tyrosine kinase inhibitors (TKI) may be of interest to combine with immunotherapy, as it has been shown that the inhibitor sunitinib reduces myeloid suppressor cells in patients with renal cell carcinoma and dasatinib promotes expansion

Josef Hammar (1868-1927) - a Swedish physician in the Anglo-Boer War (1899-1902).

It is well-known that the Anglo-Boer War attracted support and sympathy for the Boer cause from all over Europe. One topic that has not received much scholarly attention, however, is the contribution of Scandinavian medical doctors and nurses in the conflict. One of them was the Swedish surgeon Josef Hammar. This article argues that his participation was for both idealistic and pragmatic reasons.

Acetylation of intragenic histones on HPV16 correlates with enhanced HPV16 gene expression.

We report that many histone modifications are unevenly distributed over the HPV16 genome in cervical cancer cells as well as in HPV16-immortalized keratinocytes. For example, H3K36me3 and H3K9Ac that are common in highly expressed cellular genes and over exons, were more common in the early than in the late region of the HPV16 genome. In contrast, H3K9me3, H4K20me3, H2BK5me1 and H4K16Ac were more

Body mass index (BMI) and dental caries in 5-year-old children from southern Sweden.

OBJECTIVES: The aim of the present survey was to study the association between dental caries and body mass index (BMI) in Swedish preschool children (born in 1999). METHODS: A population-based and cross-sectional study design was used comprising all 920 5-year-old children in a defined area in and around the city of Lund. Anthropometric measures for the calculation of BMI were retrieved for each

Barrier properties of heat treated starch Pickering emulsions.

There is a recognized technological need for delivery systems encapsulating lipophilic substances in food and pharmaceutical products. Pickering emulsions can provide well-defined and highly stable systems, but may not provide good enough barrier properties. Starch granules, recently being used for Pickering stabilization, have the advantage of the ability to swell during gelatinization. Hence, th

Searching for doubly charged vector bileptons in the golden channel at the LHC

In this paper we investigate the LHC potential for discovering doubly charged vector bileptons considering the measurable process p, p -> e(-/+) e -/+ mu(+/-) mu(+/-) X. We perform the study using four different bilepton masses and three different exotics quark masses. Minimal LHC integrated luminosities needed for discovering and for setting limits on bilepton masses are obtained for both 7 and 1

Lack of supportive evidence for the use of immunohistochemical staining to identify occult regional lymph node metastases in primary lung cancer.

Immunohistochemical (IHC) staining for the identification of nodal occult metastases (OM), not detected by routine histological examination, has been proposed for improved staging, prognostication and decision of adjuvant treatment in surgically treated primary lung cancer. In a prospective study, we analysed 178 cases of primary lung cancer stage I-III (N0-N1) for OM by immunostaining lymph node

The parasites: Synchrotron radiation at SLAC, 1972-1992

The synchrotron radiation activities at SLAC National Accelerator Laboratory (formerly Stanford Linear Accelerator Center) started out in 1972 as a small-scale Stanford University project. The project gradually grew to become one of the first national centers for synchrotron radiation in the United States and, eventually, an independent laboratory in charge of its own accelerator machine and organ