Filtyp
Hereditary cystatin C amyloid angiopathy (HCCAA) is an autosomal dominant disorder leading to massive brain hemorrhage and death in young adults (Jensson et al., 1987). A variant of a potent inhibitor of cysteine proteinases, cystatin C (Barrett et al., 1984), is deposited as amyloid fibrils in the cerebral arteries of the patients (Ghiso et al., 1986). We have used the full length cystatin C cDNA
A need for a hand-ergonomics training kit has been identified to increase critical thinking concerning choice of hand tools. This study deals with the design, use and evaluation of a hand-ergonomics training kit for use in ergonomics training programmes. The effects on awareness of hand ergonomics among training course participants have been evaluated by means of a questionnaire and interviews at
The use of topographical data in hydrological and agricultural applications has increased with GPS data availability and the concept of precision agriculture. This thesis investigates the relationships between topography and in one case simulated soil moisture and in the other case yield. The yield was recorded with a new optical sensor, which uses a digital camera to detect objects and records th
The crustacean cuticle has numerous projections and some of these projections, the setae, have important mechanical as well as sensory functions. The setae display a wide diversity in their external morphology, which has led to great problems separating setae from other projections in the cuticle and problems in making a consistent classification system. Here, the cuticular projections on the mout
This report presents results regarding fear of crime amongst young people in a small Swedish town, Ljungby. It also considers the experience of violence and other types of crime. A questionnaire was distributed to 320 students in upper secondary school during October 2001. The results from these questionnaires shows that female students more often than male students state that they are worried whe
Objectives: To identify genetic and non-genetic risk factors for papillary serous uterine cancer. Methods: A case-control study was conducted. Case women with papillary serous uterine cancer were compared with two control groups: 1) women with endometrioid uterine cancer and 2) healthy women with no past history of cancer. Cases and controls were matched for age (within two years) and ethnic group
Metal-organic chemical vapour deposition growth of titanium oxide on moderately pre-oxidised Si(1 1 1) using the titanium(IV) isopropoxide precursor has been studied for two different growth modes, reaction-limited growth at 300 degrees C and flux-limited growth at 500 degrees C. The interfacial properties have been characterized by monitoring synchrotron radiation excited Si 2p photoemission spec
The performance of a 5' nuclease real-time PCR assay was studied to optimize an automated method of detection of preenriched Salmonella enterica cells in buffered peptone water (BPW). The concentrations and interactions of the PCR reagents were evaluated on the basis of two detection responses, the threshold cycle (C(T)) and the fluorescence intensity by a normalized reporter value (DeltaR(n)). Th
Gene therapy holds great promise for treating many genetic diseases, including muscular dystrophies. Mutations in the gene encoding laminin alpha2 chain ? an extracellular protein prominently expressed in the neuromuscular system ? cause a severe neuromuscular disorder: congenital muscular dystrophy type 1A (MDC1A). Currently, there is no treatment for MDC1A. Preclinical studies are the first step
Children's utilization of curative care was studied to analyse the division of responsibilities between undifferentiated primary care and specialized care. All chronically ill (n = 510), a control group (n = 287) and the total population 0-15 years of age (n = 6080) in a primary care district were studied using register data. Chronically ill children comprised 8.4% of the total child population an
In this paper we present a novel method for predictive coding with application to transmission of speech over packet-switched networks. Our method uses multiplexing to distribute a part of the information about a segment of each speech signal in several data packets while keeping the data packet rate and payload for that part of the information unchanged. We investigate three multiplexing schemes:
In this paper, we address some Internet core network optimization issues related to a combination of Open Shortest Path First (OSPF) and Multi Protocol Label Switching (MPLS) routing protocols. Since MPLS can be combined with any routing protocol there has appeared an idea of coupling IP streams routed via the OSPF protocol and MPLS Label Switched Paths (LSPs) in the same network. One expected adv
Searches for resonant (ν) over tilde production in e(+)e(-) collisions under the assumption that R-parity is not conserved and that the dominant R-parity violating coupling is lambda(121) or lambda(131) used data recorded by DELPHI in 1997 to 2000 at centre-of-mass energies of 183 to 208 GeV. No deviation from the Standard Model was observed. Upper limits are given for the lambda(121) and lambda(1
Interactions between the cell cycle machinery and transcription factors play a central role in coordinating terminal differentiation and proliferation arrest. We here show that cyclin-dependent kinase 6 (Cdk6) is specifically expressed in proliferating hematopoietic progenitor cells, and that Cdk6 inhibits transcriptional activation by Runx1, but not C/ EBP alpha or PU. 1. Cdk6 inhibits Runx1 acti
The finite impulse response (FIR) function of the proposed filter is realised by integrating weighted signal currents in a given time window on a capacitor. The resulting capacitor voltage becomes the filter output, periodically available between integration and reset. In such an FIR filter, the hardware cost is delinked to the number of taps,
The bioelectrocatalytical reduction of H2O2 based on direct electron transfer (ET) between polycrystalline silver and the heme containing active site of horseradish peroxidase (HRP) is studied and compared with that obtained at gold. Native HRP and recombinant wild type HRP, containing additionally a six-histidine tag at the N-terminus, NHisrHRP, have been used for adsorptive modification of the e
The remarkable variation in plumage and morphological characters in the redpoll complex Carduelis flammea-hornemanni has puzzled taxonomists for several decades. In contrast, molecular studies have not revealed any genetic differentiation among the phenotypic redpoll forms. This could either be a result of high present-day gene flow or morphological differentiation following a rapid and recent pop
