In amyloid light chain (AL) amyloidosis, amyloid fibrils derived from immunoglobulin light chain are deposited in many organs, interfering with their function. The etiology of AL amyloidosis is poorly understood. Summary data from genome-wide association studies (GWASs) of multiple phenotypes can be exploited by Mendelian randomization (MR) methodology to search for factors influencingALamyloidosi

This article seeks to recover strands of liberalism in Cambodian politics from the period leading up to Independence onwards. It uses Bell’s (2014) summative conception of the liberal tradition, which understands liberalism contextually as a constructed and contested historical phenomenon. The starting point of the analysis is liberalism from the vantage point of the present: today’s half-hearted

Background: People with Parkinson’s disease are less physically active than controls. It is important to promote physical activity, which can be assessed using different methods. Subjective measures include physical activity questionnaires, which are easy and cheap to administer in clinical practice. Knowledge of the psychometric properties of physical activity questionnaires for people with Parki

Background: Suicide in old age is a significant contributor to mortality. However, the extent to which life weariness and suicidal thoughts impact on mortality in a long-term perspective is unknown. The aim of this study was to investigate the effect of life weariness and suicidal thoughts on long-term survival (16 years) in an older Swedish population, controlling for demographic and social netwo

The Great Green Wall Initiative (GGWI) is a pan-African program launched in 2007 to combat land degradation and bring about both ecological and socio-economic benefits in the Sahel. With projects in place on only one-fifth of the targeted land and uncertainty about the extent of positive impacts, there is a need for improved monitoring and evaluation of current projects to inform the design of fut

”Invasiva främmande arter” är ett uttryck som hörs allt oftare, såväl i medier som i diskussioner vid fikabordet. Vad är då en invasiv främmande art och varför väcker dessa arter så starka känslor? Varför är de ett problem? Hur blir man av med dem? Har de några positiva egenskaper? Det är några av de frågor vi tar upp i den här boken som är ett resultat av det tvärvetenskapliga forskningstemat ”Pe

Global climate change is projected to intensify soil drying-rewetting (DRW) events with extended drought, especially in arid and semiarid ecosystems. However, the extent to which the soil DRW with intensified drought can alter soil respiration (Rs) in forests is still under debate, and subsequent legacy effects on Rs are not well understood. Here, we conducted a 180-d soil incubation experiment to

Abstract för skriften: ”Invasiva främmande arter” är ett uttryck som hörs allt oftare, såväl i medier som i diskussioner vid fikabordet. Vad är då en invasiv främmande art och varför väcker dessa arter så starka känslor? Varför är de ett problem? Hur blir man av med dem? Har de några positiva egenskaper? Det är några av de frågor vi tar upp i den här boken som är ett resultat av det tvärvetenskapl

Background: Preterm infants are susceptible to hyperglycaemia and hypoglycaemia, which may lead to adverse neurodevelopment. The use of continuous glucose monitoring (CGM) devices might help in keeping glucose levels in the normal range, and reduce the need for blood sampling. However, the use of CGM might be associated with harms in the preterm infant. Objectives: To assess the benefits and harms

Background: Clubfeet are typically shorter than normal feet. This study aimed first to describe the development of foot length in a consecutive series of children with congenital clubfoot and second to relate foot length to development of relapse and motion quality. Methods: Foot length was measured every 6 months in 72 consecutive children with congenital clubfoot (29 bilateral) aged from 2 to 7

Background: In early stage chronic obstructive pulmonary disease (COPD), dyspnea has been reported as the main symptom; but at the end of life, patients dying from COPD have a heavy symptom burden. Still, specialist palliative care is seldom offered to patients with COPD; they more often receive end of life care in hospitals. Furthermore, symptoms, symptom relief and care activities in the last we

Background: Radiation Therapy (RT) is a common treatment after breast cancer surgery and a complex process using high energy X-rays to eradicate cancer cells, important in reducing the risk of local recurrence. The high-tech environment and unfamiliar nature of RT can affect the patient’s experience of the treatment. Misconceptions or lack of knowledge about RT processes can increase levels of anx

Background: Alzheimer’s disease (AD) and other dementias currently represent the fifth most common cause of death in the world, according to the World Health Organization, with a projected future increase as the proportion of the elderly in the population is growing. Air pollution has emerged as a plausible risk factor for AD, but studies estimating dementia cases attributable to exposure to fine

Background: Several studies have assessed the Quality of Life (QoL) in Deaf and hard-of-hearing (DHH) children and adolescents. The findings from these studies, however, vary from DHH children reporting lower QoL than their typically hearing (TH) peers to similar QoL and even higher QoL. These differences have been attributed to contextual and individual factors such as degree of access to communi

Background: A novel generation of PET scanners based on silicon (Si)-photomultiplier (PM) technology has recently been introduced. Concurrently, there has been development of new reconstruction methods aimed at increasing the detectability of small lesions without increasing image noise. The combination of new detector technologies and new reconstruction algorithms has been found to increase image

PURPOSE In developing countries, Hodgkin lymphoma (HL) affects the young population. In Ethiopia, nearly 70% of the population are, 35 years of age. Therefore, this study aimed to elucidate the age distribution, histopathologic patterns, clinical characteristics and treatment outcomes of HL in Ethiopia. MATERIALS AND METHODS Data from clinical records of 133 consecutive patients with HL between 20

Context: Women with congenital adrenal hyperplasia (CAH) may present with androgen excess that is difficult to control with conventional suppressive doses of glucocorticoids. Clinical management is challenging, and the woman is at great risk of developing steroid-induced complications. Patients and Methods: A 32-year-old woman with salt-wasting CAH due to 21-hydroxylase deficiency underwent right-