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Abstract in German Bei 26 Patienten, die wegen eines Wilms-Tumors operiert wurden, wurden genetische Analysen durchgeführt. Bei 13 Kindern wurden klonal erworbene Chromosomenaberrationen gefunden, bei einem eine konstitutionelle Trisomie 18 als einzige Veränderung. Die Chromosomenzahl war bei 13 Patienten verändert. Numerische Veränderungen wurden bei 16 Kindern beobachtet und ein Bruch des ChromoIn 26 consecutive patients operated for Wilms' tumour samples from the tumour were genetically analyzed. Clonal acquired chromosome aberrations were found in 13 patients and a constitutional trisomy 18 as the sole change in 1. The chromosome number was altered in 13 patients. Numerical changes occurred in 16 patients and breakpoint of chromosome 1 in 6 patients. There was no structural alteration

Lithostratigraphy and chronostratigraphy of samples from 18 deep boreholes in Vendsyssel have resulted in new insight into the Late Weichselian glaciation history of northern Denmark. Prior to the Late Weichselian Main advance c. 23-21 kyr BP, Vendsyssel was part of an ice-dammed lake where the Ribjerg Formation was deposited c. 27-23 kyr BP. The timing of the Late Weichselian deglaciation is well

Pediobius sasae sp. nov. ( Hymenoptera: Eulophidae) is described from Japan. This new species belongs to the "eubius-complex" of species and is compared to the species of that group. It was reared from galls induced by an unidentified gall midge of the tribe Oligotrophini ( Diptera: Cecidomyiidae). The galls are formed on stems of dwarf bamboo (Sasa nipponica). Pediobius sasae is a solitary primar

Atomic spectroscopy plays an important role in fusion research and extensive knowledge of atomic parameters is needed for plasma diagnostics. However, a magnetically confined hot plasma can be considered as a spectroscopic fight source which has some unique properties, including high temperature and low density. Fusion devices can therefore be used to tackle problems in basic atomic physics. This

It has been suggested that a single photon can interfere with itself even if the difference between the two paths in the interferometer is larger than the “length” of the photon [Kessel’ and Moiseev, JETP Lett. 58, 81 (1993)]. The interference is regained by detecting the photons using a photon-echo process, where the absorbing atoms will, effectively, act as narrow-band filters. Such an experimen

The aim of this study was to determine MRI findings in patients successfully operated upon for lumbar disc herniation. We investigated 20 patients with a successful outcome after L4-5 or L5-S1 disc operations clinically and with MRI preoperatively, and at 5 days, 6 weeks, and 4 months after surgery. Postoperatively, T1- and T2-weighted images were obtained. At 4 months gadolinium-enhanced images w

The 999del5 mutation is the single, strong BRCA2 founder mutation in Iceland and the most common BRCA1/2 founder mutation in Finland. To evaluate the origin and time since spreading of the 999del5 mutation in Iceland and in Finland, we constructed haplotypes with polymorphic markers within and flanking the BRCA2 gene in a set of 18 Icelandic and 10 Finnish 999del5 breast cancer families. All Icela

Organic farming may contribute substantially to future agricultural production worldwide by improving soil quality and pest control, thereby reducing environmental impacts of conventional farming. We investigated in a comprehensive way soil chemical, as well as below and aboveground biological parameters of two organic and two conventional wheat farming systems that primarily differed in fertiliza

The closely related dioecious herbs Silene latifolia and Silene dioica are widespread and predominantly sympatric in Europe. The species are interfertile, but morphologically and ecologically distinct. A study of large-scale patterns of plastid DNA (polymerase chain reaction-restriction fragment length polymorphism) haplotypes in a sample of 198 populations from most of the European ranges of both

When a child is hospitalized, the parents find themselves in an unfamiliar environment and their parental role changes. They are in a stressful and often anxiety-filled situation and it may be difficult for them to participate in decisions. The purpose of this study was to examine the extent to which parents participate in decisions during the course of events when their child is hospitalized. Thi

Aim: To evaluate the characteristics, outcome and prognostic factors among children suffering from out of hospital cardiac arrest in Sweden. Methods: Patients aged below 18 years suffering from out of hospital cardiac arrest which were not crew witnessed and included in the Swedish cardiac arrest registry were included in the survey. This survey included the period 1990-2001 and 60 ambulance organ

Monocot residues such as corn stover and straw are often not fully exploited and constitute a potential substrate for bioethanol production. However, a number of factors such as high enzyme loadings make large-scale utilization economically difficult. Addition of non-ionic surfactants and poly(ethylene glycol) to enzymatic hydrolysis of various lignocellulosic substrates has been found to increase

The R2 protein subunit of class I ribonucleotide reductase (RNR) belongs to a structurally related family of oxygen bridged diiron proteins. In wild-type R2 of Escherichia coli, reductive cleavage of molecular oxygen by the diferrous iron center generates a radical on a nearby tyrosine residue (Tyr122), which is essential for the enzymatic activity of RNR, converting ribonucleotides into deoxyribo

Aim: To examine the prevalence and characteristics of uncontrolled hypertension (HT). Methods: A cross-sectional community-based study (1992-93) was carried out in Skara, Sweden, including 894 patients who consecutively underwent an annual follow-up at the hypertension outpatient clinic in primary care. Controlled HT was defined as diastolic blood pressure (DBP) <=90 mmHg and systolic blood press

Nanovials, microarrays, and microfluidics are brought together for the exploration of complex biological problems.

The enzyme chloroperoxidase (CPO) found in Calclariomyces fumago is able to catalyze several stereoselective oxidation reaction by using a dean oxidant, usually hydrogen peroxide (H2O2), without the need for expensive cofactor generation. CPO's lack of operational stability however, is a major limitation for its commercial use. In the present study, a capillary-LC on-line trypsin- digestion system