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In The Making : Traversing the project exhibition In the Desert of Modernity: Colonial Planning and After

The principal aim of my PhD research is to think through practices involved in the making of In the Desert of Modernity. Colonial Planning and After (Berlin 2008, Casablanca 2009), that constituted as well as traversed the exhibitions and went beyond. The project developed through a transnational constellation of culture producers, scholars, and activists from Berlin, Zurich, Paris, Delft and Casa

The Better Diabetes Diagnosis (BDD) study – A review of a nationwide prospective cohort study in Sweden

The incidence of type 1 diabetes (T1D) in Sweden is one of the highest in the world. However, the possibility of other types of diabetes must also be considered. In addition, individuals with T1D constitute a heterogeneous group. A precise classification of diabetes is a prerequisite for optimal outcome. For precise classification, knowledge on the distribution of genetic factors, biochemical mark

Elucidating recent history by tracing genetic affinity of three 16th century miners from Sweden

Objectives: Sala Silver Mine in central Sweden was an important manufacturer of silver from at least the 16th till the early 20th century, with production peaking in the 16th, mid 17th and 19th centuries. The job opportunities offered by the mine attracted people to the area resulting in the development of a small township with an associated cemetery in the vicinity of the mining center. People af

Antenatal corticosteroids : a retrospective cohort study on timing, indications and neonatal outcome

Introduction: An antenatal corticosteroid (ACS) delivery interval of 24 h to seven days is commonly referred to as optimal timing. We aimed to investigate whether the ACS delivery interval was associated with the obstetric indication for treatment and with neonatal complications. Material and methods: The study was a retrospective chart review of clinical data from preterm neonates delivered at th

Bleeding-related hospitalization in patients with von Willebrand disease and the impact of prophylaxis : Results from national registers in Sweden compared with normal controls and participants in the von Willebrand Disease Prophylaxis Network

Introduction: Patients suffering from von Willebrand disease (VWD) have a variety of bleeding symptoms and require both outpatient care for treatment and, in more severe cases, hospitalization. Aim: To investigate the impact of having VWD on frequency of hospitalization compared to a control group and to evaluate whether regular replacement therapy (prophylaxis) is associated with reduction in the

Extreme prematurity, treated retinopathy, bronchopulmonary dysplasia and cerebral palsy are significant risk factors for ophthalmological abnormalities at 6.5 years of age

Aim: This study evaluated the contributions of various prenatal and postnatal predictive factors to a documented high prevalence of ophthalmological abnormalities in children aged 6.5 years who were born extremely preterm. Methods: We carried out a prospective population-based study of all children born in Sweden at a gestational age of 22 + 0 to 26 + 6 weeks based on the Extremely Preterm Infants

Sufficiency, change, and flexibility : Critically examining the energy consumption profiles of solar PV prosumers in Sweden

The number of consumers producing electricity at home, i.e., “prosumers”, is rapidly increasing in many European countries. This article analyses the electricity consumption and energy-saving behaviours of households that own photovoltaic (PV) systems in Sweden. Earlier studies of how home production of electricity affects consumption patterns are few and their results are mixed. We interviewed pr

Phosphoproteomic insights into processes influenced by the kinase-like protein DIA1/C3orf58

Many kinases are still 'orphans,' which means knowledge about their substrates, and often also about the processes they regulate, is lacking. Here, DIA1/C3orf58, a member of a novel predicted kinase-like family, is shown to be present in the endoplasmic reticulum and to influence trafficking via the secretory pathway. Subsequently, DIA1 is subjected to phosphoproteomics analysis to cast light on i

Mid-trimester sonographic cervical consistency index to predict spontaneous preterm birth in a low-risk population

Objectives: To investigate the effectiveness of mid-trimester sonographic cervical consistency index (CCI) for the prediction of spontaneous preterm birth (sPTB) in low-risk pregnancies and to compare its performance with that of mid-trimester sonographic cervical-length (CL) measurement. Methods: This was a prospective cohort study of women with a singleton pregnancy examined by ultrasound at 19+

Associations between birth size and later height from infancy through adulthood : An individual based pooled analysis of 28 twin cohorts participating in the CODATwins project

Background: There is evidence that birth size is positively associated with height in later life, but it remains unclear whether this is explained by genetic factors or the intrauterine environment. Aim: To analyze the associations of birth weight, length and ponderal index with height from infancy through adulthood within mono- and dizygotic twin pairs, which provides insights into the role of ge

Spectrally Resolved UV Absorption Cross-Sections of Alkali Hydroxides and Chlorides Measured in Hot Flue Gases

Spectrally resolved ultraviolet (UV) absorption cross-sections of gas-phase sodium chloride (NaCl), potassium hydroxide (KOH), and sodium hydroxide (NaOH) were measured, for the first time, in hot flue gases at different temperatures. Homogenous gas-phase NaCl, KCl (potassium chloride), NaOH, and KOH at temperatures 1200 K, 1400 K, 1600 K, and 1850 K were prepared in the post-flame zone of laminar

Dickkopf-related protein 1 and gremlin 1 show different response than frizzled-related protein in human synovial fluid following knee injury and in patients with osteoarthritis

Objective: To explore the involvement of the wingless-type MMTV integration site (WNT) and bone morphogenetic protein (BMP) antagonists dickkopf-related protein 1 (DKK1), frizzled-related protein (FRZB) and gremlin 1 (GREM1) in knee injury and osteoarthritis (OA). Design: The antagonists were immunoassayed in synovial fluid from a cross-sectional cohort of nine knee healthy reference subjects, pat

IL-23R deficiency does not impact atherosclerotic plaque development in mice

Background--Interleukin-23 (IL-23) has been implicated in inflammatory and autoimmune diseases by skewing CD4+ T helper cells towards a pathogenic Th17 phenotype. In this study we investigated the presence of IL-23 receptor (IL-23R)-expressing cells in the atherosclerotic aorta and evaluated the effect of IL-23R deficiency on atherosclerosis development in mice. Methods and Results--We used hetero

Disturbed left and right ventricular kinetic energy in patients with repaired tetralogy of Fallot : pathophysiological insights using 4D-flow MRI

Objectives: Indications for pulmonary valve replacement (PVR) in patients with pulmonary regurgitation (PR) after repaired tetralogy of Fallot (rToF) are debated. We aimed to compare right (RV) and left ventricular (LV) kinetic energy (KE) measured by 4D-flow magnetic resonance imaging (MRI) in patients to controls, to further understand the pathophysiological effects of PR. Methods: Fifteen patie

‘Paranormal Reality Television: Audience Engagement with Mediums and Spirit Communication’

Reality television is a term that describes a mixture of fact and drama. We cannot understand reality television in isolation, but part of wider social and cultural phenomena, including production practices, communicative modes, and audience practices. As an inter-generic space reality television occupies the world space of observable phenomena, the dramatic space of entertainment, and the enterta

Angiotensin II type 1 receptor autoantibodies in postural tachycardia syndrome

Background--Both the adrenergic and renin-angiotensin systems contribute to orthostatic circulatory homeostasis, which is impaired in postural orthostatic tachycardia syndrome (POTS). Activating autoantibodies to the α1-adrenergic and β1/2-adrenergic receptors have previously been found in sera from patients with POTS. We hypothesized that patients with POTS might also harbor activating autoantibo

Backbone 1H, 13C, and 15N resonance assignments of the ligand binding domain of the human wildtype glucocorticoid receptor and the F602S mutant variant

The glucocorticoid receptor (GR) is a nuclear hormone receptor that regulates key genes controlling development, metabolism, and the immune response. GR agonists are efficacious for treatment of inflammatory, allergic, and immunological disorders. Steroid hormone binding to the ligand-binding domain (LBD) of GR is known to change the structural and dynamical properties of the receptor, which in tu

Leveraging accounting information systems for standardization : A case study of a SOX compliance journey

Standards, that is, a set of rules, norms or measures that establish a degree of uniformity such that idiosyncratic instances can be subjected to comparative evaluation, have long been recognized as fundamental to the production of economic efficiency. For instance, the division of labor, which underpins not only global trade but also innovation, relies on standards (Smith, 1776). Specifically, se

Integration with other data and systems

As the new generation of Information Technology is progressing at a rapid pace, with big data establishing a trend in organisations, integration between systems becomes substantial. In this chapter, we particularly look at information security as a system that has become an essential part of Business Intelligence (BI). BI systems represent one type of decision support system (DSS) with a focus on