The X-ray structures of dUTPase from equine infectious anaemia virus (EIAV) in unliganded and complexed forms have been determined to 1.9 and 2.0 A resolution, respectively. The structures were solved by molecular replacement using Escherichia coli dUTPase as search model. The exploitation of a relatively novel refinement approach for the initial model, combining maximum likelihood refinement with

No abstract is available

Cerebrospinal fluid (CSF) levels of tau, beta-amyloid(1-42) and growth-associated protein 43 (GAP-43) were studied in patients with frontotemporal dementia (FTD; n = 17), Alzheimer's disease (AD; n = 60), subcortical white-matter dementia (SWD; n = 24), Parkinson's disease (PD; n = 23) and dysthymia (n = 19) and in age-matched controls (n = 32). CSF-tau was significantly increased only in AD, and

During the last years, three rarely collected Lecidea species have been found in Skane and Halland, southernmost Sweden, viz. "Lecidea" ahlesii, L. promixta and L. confluentula. The first two are reported earlier from Sweden, but are probably overlooked. L. confluentula is new to Sweden, has been confused with L. fuscoatra, and shown here to be fairly common in western Sweden. All species are depi

Congenital mesoblastic nephroma (CMN) and infantile fibrosarcoma (IFS) are two pediatric tumors arising in the kidneys and soft tissues of infants, respectively. Recently, a t(12;15)(p13;q25) resulting in ETV6-NTRK3 gene fusion was detected in patients with IFS and in patients with the cellular type of CMN, suggesting a common pathogenetic pathway. We investigated the presence or absence of ETV6 r

Background: Research involving expressed sequence tags ( ESTs) is intricately coupled to the existence of large, well-annotated sequence repositories. Comparatively complete and satisfactory annotated public sequence libraries are, however, available only for a limited range of organisms, rendering the absence of sequences and gene structure information a tangible problem for those working with ta

This thesis presents results from two areas of research. Firstly, the resonant coherent laser techniques polarization spectroscopy (PS), degenerate four-wave mixing (DFWM) and stimulated emission (SE) have been developed in the general field of combustion diagnostics. Secondly, laser induced fluorescence (LIF) has been developed and applied for the visualization of mixture fractions in turbulent n

Male black cutworm moths (Agrotis ipsilon, Lepidoptera, Noctuoidea, Noctuidae), which are attracted by a three-component pheromone blend ((Z)-7-dodecenyl acetate, Z7-12:Ac; (Z)-9-tetradecenyl acetate, Z9-14:Ac; (Z)-11-hexadecenyl acetate, Z11-16:Ac), express diverse antennal pheromone binding proteins (PBPs). Two PBP isoforms (Aips-1 and Aips-2) that show 46% identity were cloned from antennal cDN

Purpose: To describe the MR appearance of acute cholangitis and discuss the role of MR imaging as a diagnostic method in this disease. Material and Methods: Of 60 patients with clinical acute cholangitis, 12 were examined with MR before endoscopic retrograde pancreatography (ERCP). A retrospective review was performed of MR and ERCP findings. The MR findings registered were presence of biliary duc

Background. Dehiscence of colon anastomosis is a common, serious and potentially life-threatening complication after colorectal operation. In experimental models, impaired biomechanic strength of colon anastomoses is preventable by general inhibitors of matrix metalloproteinases (MMPs) and associated with collagen loss, which indicates a possible link between MMP-mediated collagen degradation and

BACKGROUND: Proteinuria, due to impairment of the charge- and/or size selectivity of the glomerular capillary wall (GCW) is the earliest clinical evidence of diabetic nephropathy (DN). To study the pathophysiological differences between patients with DN in type 1 diabetes mellitus (type 1 DN) and type 2 diabetes mellitus (type 2 DN), we compared the patterns of urinary proteins of different size a

A major drawback of the defibration or refining process in manufacturing pulp is that of its large energy requirements. If the mechanics of the process were better understood, large amounts of energy could probably be saved. The initial defibration seems to be crucial for both the quality of the pulp and the total consumption of energy. Numerical simulations by means of the finite element method r

The moult migration of Greylag Geese Anser anser from Scania, southernmost Sweden, was studied based on resightings of neck-banded individuals marked in the breeding areas. Most geese seen in moulting areas were recorded in the marking area both before and after moult. Lip to 1992, 72% of all neck-banded Greylag Geese recorded front a moulting area were reported from Oostvaardeusplassen in the Net

Mice deficient for SPI-group ETS transcription factors PU.1 or SPI-B fail to generate lymphocytes or do not mount normal antibody mediated immune responses, respectively. PU.1 expression is restricted to B-, T-lymphocytes and macrophages, while SPI-B is expressed in B- and T-lymphocytes. SPI-C is an ETS transcription factor closely related to PU.1 and SPI-B, and expressed temporarily during B-cell

A postal survey was carried out to determine the clinical and legal guidelines governing the use of electroconvulsive therapy (ECT) in the countries of the wider Europe. Respondents from 23 of the 33 countries returned completed questionnaires. Considerable variation was found in the availability of ECT, the frequency of its use and associated legal procedures. However, there was a broad consensus

Popular Abstract in Swedish För att tillverka produkter av hög kvalitet, behöver industriella företag strukturera arbetet med hjälp av instruktioner och riktlinjer som är lätta att förstå och komma åt. Dessa samlas ofta i en eller flera pärmar eller på internt datornätverk, ofta som en del av den internationella kvalitetsstandarden ISO 9000. Men detta fungerar sällan som ett välfungerande stöd förIndustrial companies supply products intended to satisfy customers’ needs and requirements. To be competitive and to maintain good economic performance, efficient systems are needed to communicate information and exchange knowledge. Such systems are often referred to as quality systems as they intend to support development as well as standardized work regarding the quality of the product and incre

BACKGROUND: Roux-en-Y gastric bypass is a bariatric procedure of choice. There is evidence supporting a small isolated pouch and a wide anastomosis. Gastric vascular anatomy renders the ventral aspect less suited for anastomotic construction. The lesser curvature has abundant blood supply that should preferably not be interfered with. Terminal anastomosis is a logical choice. METHODS: We devised a

In this paper we trace the establishment of the graduate school in mathematics education in Sweden. To provide a useful context for this initia-tive we review briefly the evolution of the PhD, the development of doctoral degrees and doctoral programmes in mathematics departments in Sweden, as well as the growing popularity of graduate schools. Progress and pro-gramme issues encountered to date are

Efter tre års så kallad djungelregim (jungle raj) under Mulayam Singh Yadavs ledning, återkommer nu dalitledaren Mayawati till makten på eget mandat i Uttar Pradesh, Indiens folkrikaste delstat. I det utdragna valet, vars resultat blev klart den 11 maj 2007, vann hon och hennes parti Bahujan Samaj Party (BSP) en absolut majoritet med 206 mandat i delstatförsamlingen.