Simulations of Osmotic Ultrafiltration Failure in CAPD Using a Serial Three-Pore Membrane/Fiber Matrix Model.
Ultrafiltration failure ( UFF) is a common complication of long- term peritoneal dialysis ( PD). Functionally UFF is in most cases characterized by an enhanced peritoneal mass transfer area coefficient for glucose ( PSg) combined with a largely unchanged peritoneal glucose osmotic conductance ( LpS sigma(g)). Morphologically, marked UFF occurs with fibrosis of the submesothelial zone in the perito