Sökresultat

Filtyp

Din sökning på "*" gav 541800 sökträffar

Mid-infrared polarization spectroscopy of polyatomic molecules: Detection of nascent CO2 and H2O in atmospheric pressure flames

We report the application of mid-infrared polarization spectroscopy (IRPS) for detection of nascent CO2 and H2O in atmospheric pressure flames. The recorded IRPS spectra demonstrated both the quantitative nature of the method and the suppression of strong infrared emission from flames. In spite of the high line-density of the hot polyatomic ro-vibrational spectrum, lines belonging to different CO2

Preparation, crystallization and preliminary X-ray analysis of protein YtlP from Bacillus subtilis

Bacillus subtilis YtlP is a protein that is predicted to belong to the bacterial and archael 2'-5' RNA-ligase family. It contains 183 residues and two copies of the HXTX sequence motif conserved among proteins belonging to this family. In order to determine the structure of YtlP and to compare it with the paralogue YjcG and identified 2'-5' RNA ligases, the gene ytlP was amplified from B. subtilis

Timolol increased retrobulbar flow velocities in untreated glaucoma eyes but not in ocular hypertension

PURPOSE: To investigate retrobulbar blood flow velocities and the effects of topical timolol treatment in eyes with newly detected, previously untreated open angle glaucoma or ocular hypertension. METHODS: Fifteen eyes with open angle glaucoma (OAG) and 12 eyes with ocular hypertension (OH), in the same number of patients, all untreated and newly detected, were examined with colour Doppler imaging

Unique features of the insulin receptor in rat brain

We examined the structure of the affinity-labeled insulin receptors in rat brain, rat liver, and human IM-9 lymphocytes using sodium dodecyl sulfate-polyacrylamide gel electrophoresis. In gels run under reducing conditions, the alpha-subunit of the insulin receptor in brain had an apparent Mr of 127,000 distinctly lower than that seen in both rat liver and human lymphocytes (apparent Mr = 136,000)

Samhällsekonomiska studier av diabetes behövs. Ger underlag för beslutsfattande och för internationella jämförelser

Cost-of-illness studies have shown diabetes to be associated with substantial direct and indirect costs, accounting for 5-6 percent of total health care expenditure. In a Swedish study, where total costs were divided into costs due to management of diabetes and costs due to complications, the total annual cost to the community was estimated to be SEK 5.7 billion in 1994, costs due to complications

L-carnitine and haemodialysis: double blind study on muscle function and metabolism and peripheral nerve function

Twenty-eight haemodialysis patients were randomized to L-carnitine, 2 g i.v. three times a week, and saline over a 6-week period. No obvious deficiency of carnitine was found in vastus lateralis with a median value of 12.9 mmol/kg dry weight; range 6.2-21.4. Female patients had lower total plasma carnitine compared to female controls, p less than 0.002, whereas no decrease was found in males. No r

An Integrated Technique for Test Vector Selection and Test Scheduling under Test Time Constraint

The quality of test is highly related to the number of faults that can be detected during the testing (fault coverage) and the defect probability of each testable unit. High test quality is reached by applying an excessive number of good test vectors, however, such a high test data volume can be problematic to fit in the ATE's (automatic test equipment) limited memory. We therefore propose, for co

Diabetes mellitus--nya svenska nationella riktlinjer

In 1996, national guidelines for the care and treatment of patients with diabetes mellitus were drawn up by specialists, in collaboration with representatives of the patient organisation, diabetes nurses, the professional associations of various medical specialties and central authorities. The national programme is divides into three parts: summarised information for decision-makers, clinical guid

Generation of midbrain dopaminergic neurons in vivo and in vitro: the role of Neurogenin2

Popular Abstract in Swedish I hjärnan finns många olika typer av nervceller. De använder sig av olika signalsubstanser, kallade neurotransmittorer, för att kommunicera med andra nervceller. En viss typ av nervceller använder neurotransmittorn dopamin. Dopaminceller finns på många ställen i hjärnan men de flesta ligger i mellanhjärnan i ett par olika cellgrupper som var och en skickar signaler tillParkinsons disease (PD) is a neurodegenerative disorder where dopaminergic neurons of the substantia nigra (SNc) in the mesencephalon are progressively eliminated. The ensuing loss of dopaminergic innervation of the basal ganglia manifests itself as severe motor deficits in PD patients. Clinical trials have shown that cell replacement therapy, where dopaminergic neuroblasts derived from fetal vent

Studies in building physics : dedicated to professor Lars Erik Nevander on his 60th anniversary, November 11, 1981

Preface: This report has been produced in order to celebrate the 60th anniversary of professor Lars Erik Nevander on the 11th of November, 1981. A number of topics are presented within the field of building physics. They relate to heat transfer in buildings, air infiltration, moisture darnages etc, varying from energy conservation aspects to failures of the building and its design for moisture pro

A rapid and simple ABO genotype screening method using a novel B/O2 versus A/O2 discriminating nucleotide substitution at the ABO locus

An ABO genotype screening method discriminating the common alleles A1, A2, B, O1 and O2 at the ABO locus was made possible by the discovery of a novel nucleotide substitution (G1096A) present only in B and O2 alleles. A rapid and reliable single-tube approach using multiplex PCR with four primers amplifying exons 6 and 7 of the ABO genes followed by simultaneous addition of two restriction enzymes

A distributed capacitance analysis of co-planar inductors for a CMOS QVCO with varactor tuned buffer stage

A quadrature voltage controlled oscillator (QVCO) topology exhibiting low power consumption and high phase noise performance at low supply voltages is presented. The QVCO buffer includes varactors to maximize the output voltage and minimize the current consumption. Microstrip theory and the principle of conservation of energy have been used to evaluate the distributed capacitances of symmetrical i

Pathophysiology of bone metastases in prostate cancer

Objective: Men with advanced prostate cancer are at high risk for bone metastases that result in significant skeletal morbidity. This review discusses the pathophysiology of bone metastases in prostate cancer. Methods: Relevant information was identified through searches of published studies, abstracts from scientific meetings, and review articles. Results: Bone metastases are common in patients w

Molecular and structural characterization of five novel mutations in the Bruton's tyrosine kinase gene from patients with X-linked agammaglobulinemia

Background: The Btk (Bruton's tyrosine kinase) gene has been shown to be mutated in the human immunodeficiency disease, XLA (X-linked agammaglobulinemia). Btk is a member of the Tec family of cytosolic protein tyrosine kinases with distinct functional domains PH, TH, SH3, SH2, and kinase. Mutations have been observed in each of the Btk subdomains in XLA. We have analyzed the Btk gene in six XLA pa