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Differences in prolactin receptor (PRLR) in mouse and human fallopian tubes: Evidence for multiple regulatory mechanisms controlling PRLR isoform expression in mice

The anterior pituitary-derived hormone prolactin (PRL) signals through the PRL receptor (PRLR) and is important for female reproductive function in mammals. In contrast to the extensive studies of PRLR expression and regulation in human and mouse ovary and uterus, the mechanisms controlling the regulation of PRLR isoform expression in the fallopian tube are poorly understood. Because dynamic inter

Dietary amino acids influence plumage traits and immune responses of male house sparrows, Passer domesticus, but not as expected

Traits that influence social interactions (signals) are widely thought to be honest indicators of some underlying quality of their bearer. One hypothesis is that a signal and the bearer's immunocompetence are linked via a condition-dependent pathway. We tested this idea by measuring the effect of specific dietary components on the development of a melanin-based plumage signal and the production of

Ostracod stable isotope records from a deglacial isolation sequence in southern Sweden

A Late Weichselian sediment succession from the Kullen Peninsula, southern Sweden, was studied by means of stable carbon and oxygen isotope analyses of calcitic valves of selected ostracod taxa. The lower part of the record was deposited in a slightly brackish marginal sea close to the receding inland ice, whereas the upper part is lacustrine in origin as a result of glacio-isostatic rebound. The

Geophysical and hydrogeologic investigation of groundwater in the Karoo stratigraphic sequence at Sawmills in northern Matabeleland, Zimbabwe: a case history

Geophysical and hydrogeological investigations have been carried out around Sawmills in Zimbabwe, Africa. The investigations are components of a larger investigation to assess the groundwater potential of the Karoo sedimentary basin with regards to supplying water to Bulawayo City. The Sawmills area was selected due to the availability of borehole logs indicating favourable stratigraphy for ground

GABA, a natural immunomodulator of T lymphocytes.

gamma-aminobutyric acid (GABA) is the main neuroinhibitory transmitter in the brain. Here we show that GABA in the extracellular space may affect the fate of pathogenic T lymphocytes entering the brain. We examined in encephalitogenic T cells if they expressed functional GABA channels that could be activated by the low (nM-1 microM), physiological concentrations of GABA present around neurons in t

Band alignment at the ZrO2/Si(100) interface studied by photoelectron and x-ray absorption spectroscopy

We present measurements of the Zr and Si core level photoelectron binding energies relative to the Fermi level and the vacuum level under a ZrO2 growth series on Si(100). It is shown that the Zr core level binding energy is most properly referenced to the local vacuum level already from the monolayer regime. This confirms the insulating properties of ZrO2. The Si core levels are referenced to the

Automated reporting from gel-based proteomics experiments using the open source Proteios database application

The assembly of data from different parts of proteomics workflow is often a major bottleneck in proteomics. Furthermore, there is an increasing demand for the publication of details about protein identifications due to the problems with false-positive and false-negative identifications. In this report, we describe how the open-source Proteios software has been expanded to automate the assembly of

ADHD in adult psychiatry. Minimum rates and clinical presentation in general psychiatry outpatients.

The objective of the study was to determine the prevalence and comorbidity of persisting attention-deficit hyperactivity disorder (ADHD) in adult psychiatric outpatients. Consecutive patients, first visits excluded, at a general psychiatric outpatient clinic were offered a screening for childhood ADHD with the Wender Utah Rating Scale (WURS). One hundred and forty-one patients out of 398 (35%) com

Aspects of estimating parameter dependencies in a detailed chromatography model based on frontal experiments

A methodology for estimation of the dependency on flow rate and bead size of the axial dispersion coefficient and the film mass transfer coefficient in a detailed model for chromatographic processes is proposed. The model describes the concentration of the solute in the mobile phase and considers external/internal mass transfer resistance. The flow rate dependency of the mixing effect in the exter

Distributed colouring and communication in rings with local knowledge

We consider two interrelated tasks in a synchronous n-node ring: distributed constant colouring and local communication. We investigate the impact of the amount of knowledge available to nodes on the time of completing these tasks. Every node knows the labels of nodes up to a distance r from it, called the knowledge radius. In distributed constant colouring every node has to assign itself one out

Type III cGMP-inhibited cyclic nucleotide phosphodiesterases (PDE3 gene family)

Seven different but related cyclic nucleotide phosphodiesterase (PDE) gene families have been identified. Type III cGMP-inhibited (cGI) PDEs, the PDE3 gene family, are found in many tissues. cGI PDEs exhibit a high affinity for both cAMP and cGMP, and are selectively and relatively specifically inhibited by certain agents which augment myocardial contractility, promote smooth muscle relaxation and

Maintenance of dominance is mediated by urinary chemical signals in male European lobsters, Homarus gammarus

We studied the relevance of urine cues in Homarus gammarus dominance maintenance, hypothesising that urinary signals are necessary to mediate recognition of former opponents. Males in size-matched pairs interacted on two consecutive days with or without blocking urine release by adding catheters to both contestants on the second day. European lobsters established dominance in a first fight, and fi

Nationalism and Historicity

In this article the nation is shown to be a historical subject. As such, it is constructed and constantly reconstructed by discursive practices of power and knowledge. The author argues that the symbiotic interlinkage between nationalism and the organising knowledge principle of historicity, is an example of a power practice in the modern state. Throughout the article, it is shown that this practi

Fecal water from ileostomic patients consuming oat beta-glucan enhances immune responses in enterocytes

Yeast, fungal, and dietary beta-glucans have immune-modulating effects in vitro and in vivo, as thought, mainly by affecting leukocytes; however, effects of oat beta-glucan on enterocytes have never been studied. As recognized, supplying oat beta-glucans as such to cells in culture directly is difficult because of solubility problems. Therefore, six ileostomic patients consumed, in random order, a

GABAB receptors within the ventral tegmental area are involved in the expression and acquisition of morphine-induced place preference in morphine-sensitized rats

The influence of intra-ventral tegmental area administration of gamma-amino-butyric-acid-B (GABAB) receptor agonist and antagonist on the expression and acquisition of morphine-induced conditioned place preference (CPP) in morphine-sensitized female rats was examined. Our pilot experiment showed that subcutaneous administration of morphine-(2.5, 5 and 7.5 mg/kg) induced CPP. Administration of one

Propagation in bianisotropic media-reflection and transmission

A systematic analysis for solving the wave propagation problem in a general bianisotropic, stratified medium is presented. The method utilises the concept of propagators, and the representation of these operators is simplified by introducing the Cayley-Hamilton theorem. The propagators propagate the total tangential electric and magnetic fields in the slab and only outside the slab do the up- and