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Intruder bands in Te114 : Smooth band termination
The nucleus Te114 has been studied in heavy-ion -ray spectroscopy experiments performed with the early implementation of the GAMMASPHERE multidetector array. Three rotational intruder bands have been observed up to high spins. The yrast band, involving the 4p2h (h11/2)2(g7/2)2(g9/2)-2 proton configuration, reaches I=48Latin small letter h with stroke at an excitation energy of 30.3 MeV, the highes
Evaluation of knowledge, experiences, and fear toward prescribing and dispensing corticosteroids among Egyptian healthcare professionals : A cross-sectional study
Background: Corticosteroids (CS) are essential drugs in the treatment of several medical conditions. Assuming different roles, physicians and pharmacists play a primary role in prescribing and dispensing these medications to optimize patients' clinical management. The data on assessing knowledge and experience of healthcare professionals toward CS is scarce. Therefore, this study aimed to assess a
‘SAXS-osmometer’ method provides measurement of DNA pressure in viral capsids and delivers an empirical equation of state
We present a novel method that provides a measurement of DNA pressure in viral capsids using small angle X-ray scattering (SAXS). This method, unlike our previous assay, does not require triggering genome release with a viral receptor. Thus, it can be used to determine the existence of a pressurized genome state in a wide range of virus systems, even if the receptor is not known, leading to a bett
Particle lung deposited surface area (LDSAal) size distributions in different urban environments and geographical regions : Towards understanding of the PM2.5 dose–response
Recent studies indicate that monitoring only fine particulate matter (PM2.5) may not be enough to understand and tackle the health risk caused by particulate pollution. Health effects per unit PM2.5 seem to increase in countries with low PM2.5, but also near local pollution sources (e.g., traffic) within cities. The aim of this study is to understand the differences in the characteristics of lung-
Innovations, informality, and the global south : A thematic analysis of past research and future directions
The informal sector of the global south has lately started to gain attention from innovation and development studies scholars. Studies highlighting the determinants, barriers, social processes, and institutions that influence innovations in the informal sector have enriched the discussion on the topic. This paper analyzes the existing body of knowledge at the intersection of the informal sector, i
Nils Månsson Mandelgrens dokumentation av Sveriges medeltidskyrkor
The Benefits and Harms of Pharmacological Treatment for Postradiation Pelvic Pain : A Systematic Review by the European Association of Urology Chronic Pelvic Pain Panel with Recommendations for Clinical Practice
Context: Radiotherapy of the pelvis is a widely used method for the treatment of malignancies, and local complications including pain following pelvic radiation therapy are acknowledged complications. Objective: The primary objective is to assess the clinical effectiveness and safety of pharmacological therapies on postradiation pelvic pain. Evidence acquisition: A systematic review of the use of
The importance of business travel for trade : Evidence from the liberalization of the Soviet airspace
The strong negative relationship between geographical distance and trade is not well understood. I use the liberalization of the Soviet airspace to estimate the causal impact of business travel cost on trade. The liberalization radically reduced travel time between Europe and East Asia and was followed by a significant increase in trade. I find that the cost of business travel can account for a la
Toward standardization in reporting data on basic human semen examination : A crucial step in advancing the field of andrology and reproductive medicine
A highly-detailed anatomical study of left atrial auricle as revealed by in-vivo computed tomography
The left atrial auricle (LAA) is the main source of intracardiac thrombi, which contribute significantly to the total number of stroke cases. It is also considered a major site of origin for atrial fibrillation in patients undergoing ablation procedures. The LAA is known to have a high degree of morphological variability, with shape and structure identified as important contributors to thrombus fo
Charles Bonnet Syndrome Adversely Affects Vision-Related Quality of Life in Patients with Glaucoma
Purpose: To investigate the impact of Charles Bonnet syndrome (CBS) on vision-related quality of life (VRQoL) in patients with glaucoma. Design: Cross-sectional cohort study. Participants: Twenty-four patients with CBS and 42 matched controls without CBS out of 337 patients with open-angle glaucoma (OAG) with visual field (VF) loss. Methods: A matching technique was used to identify control patien
Irreversible electroporation of hepatocellular carcinoma and colorectal cancer liver metastases : A nationwide multicenter study with short- and long-term follow-up
Introduction: A nationwide multicenter study was performed to examine short- and long-term effects of irreversible electroporation (IRE) for hepatocellular carcinoma (HCC) and colorectal cancer liver metastases (CRCLM). IRE is an alternative method when thermal ablation is contraindicated because of risk for serious thermal complications. Methods: All consecutive patients in Sweden treated with IR
Linearly convergent nonoverlapping domain decomposition methods for quasilinear parabolic equations
We prove linear convergence for a new family of modified Dirichlet–Neumann methods applied to quasilinear parabolic equations, as well as the convergence of the Robin–Robin method. Such nonoverlapping domain decomposition methods are commonly employed for the parallelization of partial differential equation solvers. Convergence has been extensively studied for elliptic equations, but in the case o
The archaeometry of tuyeres from the Great Zimbabwe and wider implications for its iron production technologies
AbstractRecent research in the wider archaeological landscape of Great Zimbabwe recovered moreevidence of metallurgical tuyeres fused in varied multiples indicative of their use in natural draft iron smelting technologies. We report the first detailed chemical, microstructural and thermal analyses of these ceramic materials most likely associated with large-scale iron production at the zenith of tWe report the first detailed chemical, microstructural and thermal analyses of a growing corpus of metallurgical tuyeres from the wider archaeological landscape of Great Zimbabwe in southern Africa. Of note is the fusion of the tuyeres in multiples, suggestive of widespread use of natural draft iron smelting technologies for large-scale production of iron most likely during the zenith period of Gr
A Model System for Feralizing Laboratory Mice in Large Farmyard-Like Pens
Laboratory mice are typically housed under extremely clean laboratory conditions, far removed from the natural lifestyle of a free-living mouse. There is a risk that this isolation from real-life conditions may lead to poor translatability and misinterpretation of results. We and others have shown that feral mice as well as laboratory mice exposed to naturalistic environments harbor a more diverse
Pivotal advance : CD45RB glycosylation is specifically regulated during human peripheral B cell differentiation
A screen of cell surface markers differentially expressed during peripheral B cell differentiation identified that the CD45RB epitope detected by the mAb MEM-55 was highly expressed on CD27+ memory B cells and absent on CD27- naïve B cells. IgG+CD27- memory and a previously unacknowledged CD27- population in blood also expressed high levels of CD45RBMEM55. Naïve and memory B cells from tonsils fol
Serum-IgG responses to SARS-CoV-2 after mild and severe COVID-19 infection and analysis of IgG non-responders
Background To accurately interpret COVID-19 seroprevalence surveys, knowledge of serum-IgG responses to SARS-CoV-2 with a better understanding of patients who do not seroconvert, is imperative. This study aimed to describe serum-IgG responses to SARS-CoV-2 in a cohort of patients with both severe and mild COVID-19, including extended studies of patients who remained seronegative more than 90 days
A unique role of the cholera toxin A1-DD adjuvant for long-term plasma and memory B cell development
Adjuvants have traditionally been appreciated for their immunoenhancing effects, whereas their impact on immunological memory has largely been neglected. In this paper, we have compared three mechanistically distinct adjuvants: aluminum salts (Alum), Ribi (monophosphoryl lipid A), and the cholera toxin A1 fusion protein CTA1-DD. Their influence on long-term memory development was dramatically diff
Conserved sequence elements in K promoters from mice and humans : Implications for transcriptional regulation and repertoire expression
Promoter region sequences of human and mouse Igk-V genes were aligned and found to be conserved for about 200-300 base pairs (bp) within subgroups/families. No promoter similarity was found between IGKV promoters from different human subgroups. Related mouse Igk-V gene families were conserved in the promoter region but no similarity was evident when promoters from unrelated Igk-V gene families wer