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Waist-hip ratio (WHR) is a measure of body fat distribution and a predictor of metabolic consequences independent of overall adiposity. WHR is heritable, but few genetic variants influencing this trait have been identified. We conducted a meta-analysis of 32 genome-wide association studies for WHR adjusted for body mass index (comprising up to 77,167 participants), following up 16 loci in an addit
In a broad range of species-including humans-it has been demonstrated that telomere length declines throughout life and that it may be involved in cell and organismal senescence. This potential link to ageing and thus to fitness has triggered recent interest in understanding how variation in telomere length is inherited and maintained. However, previous studies suffer from two main drawbacks that
The present thesis is aimed to examine the hypothesis that the degree of vascular inflammation correlates with the expression of vascular endothelin and angiotensin receptors. The receptor changes were studied in subcutaneous resistance arteries in patients with different degrees of ischemic heart disease (IHD). In addition, patients with giant cell arteritis (GCA) were also investigated because o
Popular Abstract in Swedish Båtbenet är ett lite ben i handloven som är väsentlig för handledens funktion. Båtbenet kan skadas om man ramlar och tar emot med handen, och den skadade är ofta en ung man, som inte sällan håller på med sport. Man ser ingen felställning på handledens utsida, men patienten upplever ofta smärta på handledens tummsida. Röntgen har svårt att påvisa ett brott, eftersom båtbAbstract The scaphoid is the most commonly fractured carpal bone. The diagnosis is difficult and untreated the long-term results are poor. Approximately 10% do not unite even if they are treated properly. The aim of this thesis was to study scaphoid fracture epidemiology, diagnosis and treatment. During a four-year period (2004-03-01 to 2008-02-28) all patients attending the Emergency Department a
In this paper, we consider dynamical subsystems interconnected in a broadcast architecture. In the broadcast-out case, the root node can affect several leaf nodes, but the leaf nodes do not affect any other nodes. Each subsystem is locally controlled via output feedback, and the controllers can communicate according to a structure that parallels the dynamic coupling between subsystems. Explicit st
Despite the central role played by human capital in entrepreneurship, little is known about how employees in entrepreneurial firms are compensated and incentivized. We address this gap in the literature by studying 18,935 non-CEO compensation contracts across 1,809 privately held venture-backed companies. Our key finding is that employee compensation varies with the degree to which VCs versus foun
In this paper, we present a new color buffer compression algorithm for floating-point buffers. It can operate in either an approximate (lossy) mode or in an exact (lossless) mode. The approximate mode is error-bounded and the amount of introduced accumulated error is controlled via a few parameters. The core of the algorithm lies in an efficient representation and color space transform, followed b
"When we celebrate the days of our deceaced brothers" -- texts for the Office of the dead in Liber daticus vetustior
Tissue factor pathway inhibitor 2 (TFPI-2) is a matrix-associated serine protease inhibitor with an enigmatic function in vivo. Here, we describe that TFPI-2 is present in fibrin of wounds and also expressed in skin, where it is up-regulated upon wounding.
I Indonesien pågår en livlig aktivitet kring hur man bör tolka kvinnors rättigheter inom den muslimska läran. Insikten om genus betydelse står högt på agendan inom forskning och utbildning; vid flera universitet skrivs kursplaner och kurslitteratur utifrån ett genusperspektiv. Även utanför akademien pågår islambaserat arbete för att stärka kvinnors rättigheter. Ett exempel är information om hiv oc
The on-going excavation campaign at Uppåkra in Scania began in 1996 and the site has seen fieldwork annually since. The archaeology covers c. 40 hectares and represents continuous settlement from c 100 BC to AD 1000. Trial trenches have been scattered across the site, with a concentration to what is now seen as the most important part, the residence. Here the foundation of an apparently cultic bui
Diode laser absorption spectroscopy was utilized for non-intrusive assessment of gas content in human body cavities, including intestines and lungs of a new-born, the mastoid bone, and sinus cavities for monitoring sinusitis recovery in adults.
One of the most important measures of offspring performance is growth rate, which is often traded off against another important survival trait, immune function. A particular feature of ostrich chicks maintained in farmed environments is that cohorts of chicks vary widely in size. As parents can have a profound effect on the phenotype and fitness of their offspring, we investigated whether chick gr
This article contributes to ongoing debates on how bottom-up social cooperation can halt and reverse processes of environmental and human degradation, dispossession and impoverishment, by proposing a synchronization of resistance and of commoning practices. The article moves from the empirical case of social and ecological conflicts currently unfolding in the so-called Land of Fires, an area in So
We have studied the oxidation of CO over Rh(100) using high pressure x-ray photoelectron spectroscopy under CO and O2 pressures ranging from 0.01 to 1 mbar. The results show a very low or no conversion for the CO covered surface found at low temperatures, while the activity rises slightly when the temperature is high enough for some CO to desorb, exposing surface sites for dissociative O2 adsorpti
The electromagnetic (EM) coupling between metal nanoparticles (NPs) is of essential importance in nanoplasmonic systems, leading to a variety of fundamental studies and practical applications. The successive investigations in this field not only bring forward surprising optical effects in nanoplasmonics, but also allow revealing other novel chemical/physical properties in relevant systems. In this
Studies on fetal lung/brain circulation by means of power Doppler technique have suggested a marked reduction in lung perfusion in high-risk pregnancies as a sign of circulation redistribution. The ratio between lung/brain perfusion might therefore give a new method to predict fetal circulation centralization. Objective: The aim of the present study was to obtain fetal lung and cerebral artery rat
