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The "International Society for Heart and Lung Transplantation Guidelines for the Evaluation and Care of Cardiac Transplant Candidates-2024" updates and replaces the "Listing Criteria for Heart Transplantation: International Society for Heart and Lung Transplantation Guidelines for the Care of Cardiac Transplant Candidates-2006" and the "2016 International Society for Heart Lung Transplantation Lis
Alzheimer's disease (AD) is a debilitating neurodegenerative disorder characterized by the accumulation of β-amyloid (Aβ) peptides and phosphorylated tau (P-tau) proteins in the brain, leading to cognitive decline and memory impairment. Despite extensive research, the exact mechanisms of AD pathogenesis remain elusive, and reliable biomarkers for early diagnosis and disease monitoring are still ne
Hazel (Corylus avellana) has been abundant in the vegetation of northern and central Europe since the early Holocene and has provided food and materials for humans ever since. Here we use stable carbon isotope (δ13C) values of hazelnut shells to infer woodland openness based on the premise of the “canopy effect”. It is well established that plants growing in dense, shaded forests have lower carbonHazel (Corylus avellana) has been abundant in the vegetation of northern and central Europe since the early Holocene and has provided food and materials for humans ever since. Here we use stable carbon isotope (δ13C) values of hazelnut shells to infer woodland openness based on the premise of the “canopy effect”. It is well established that plants growing in dense, shaded forests have lower carbon
This paper reports cross-section measurements of ZZ production in pp collisions at s=13.6TeV at the Large Hadron Collider. The data were collected by the ATLAS detector in 2022, and correspond to an integrated luminosity of 29 fb−1. Events in the ZZ→4ℓ (ℓ=e, μ) final states are selected and used to measure the inclusive and differential cross-sections in a fiducial region defined close to the anal
A search for high-mass resonances decaying into a Formula Presented-lepton and a neutrino using proton-proton collisions at a center-of-mass energy of Formula Presented is presented. The full run 2 data sample corresponding to an integrated luminosity of Formula Presented recorded by the ATLAS experiment in the years 2015-2018 is analyzed. The Formula Presented-lepton is reconstructed in its hadro
Introduction: Prolonged progress can occur in the first and second stages of labour and may contribute to a negative birth experience. However, previous studies have mainly focused on quantitative aspects or overall birth experience, and little is known about women's experiences of a prolonged passive second stage. Objective: To describe the lived experiences of a prolonged passive second stage of
While organisms have evolved to cope with predictable changes in the environment, the rapid rate of current global change presents numerous novel and unpredictable stressors to which organisms have had less time to adapt. To persist in the urban environment, organisms must modify their physiology, morphology and behaviour accordingly. Metabolomics offers great potential for characterising organism
Background: Inflammatory bowel disease (IBD) is characterized by recurrent inflammation of the gastrointestinal tract and has been linked to an imbalance in gut bacteria. Synbiotics, which combine probiotics and prebiotics, are emerging as potential IBD treatments. Aim: To examine the effects of four synbiotic formulations on intestinal inflammation and peripheral biomarkers in a rodent IBD model
The market for artificial sweeteners as substitutes for conventional sugar (sucrose) is growing, despite potential health risks associated with their intake. Estimating population usage of artificial sweeteners is therefore crucial, and wastewater analysis can serve as a complement to existing methods. This study evaluated spatial and temporal usage of artificial sweeteners in five Swedish communi
This paper presents a study of Z→llγ decays with the ATLAS detector at the Large Hadron Collider. The analysis uses a proton–proton data sample corresponding to an integrated luminosity of 20.2 fb-1 collected at a centre-of-mass energy s = 8 TeV. Integrated fiducial cross-sections together with normalised differential fiducial cross-sections, sensitive to the kinematics of final-state QED radiatio
Background: The absence of Epithelial Membrane Protein 3 (EMP3) on red blood cells (RBCs) underlies the MAM-negative (MAM−) phenotype. EMP3 is a ubiquitous protein found at low levels in most tissues but with higher expression in hematopoietic cells. Low levels of CD44 are a signature of MAM− RBCs due its proposed physical interaction with EMP3, indicating that EMP3 stabilises CD44 in the membrane
Higgsinos with masses near the electroweak scale can solve the hierarchy problem and provide a dark matter candidate, while detecting them at the LHC remains challenging if their mass splitting is O(1 GeV). This Letter presents a novel search for nearly mass-degenerate Higgsinos in events with an energetic jet, missing transverse momentum, and a low-momentum track with a significant transverse im
Background: Polygenic prediction studies in continental Africans are scarce. Africa’s genetic and environmental diversity pose a challenge that limits the generalizability of polygenic risk scores (PRS) for body mass index (BMI) within the continent. Studies to understand the factors that affect PRS variability within Africa are required. Methods: Using the first multi-ancestry genome-wide associa
Background: As global aging accelerates, routinely assessing the functional status and morbidity burden of older patients becomes paramount. The aim of this study is to assess the validity of the comprehensive clinical and functional Health Assessment Tool (HAT) based on four cohorts of older adults (60 + years) from the Swedish National study on Aging and Care (SNAC) spanning urban, suburban, and
Daylight analysis informs design decisions in architectural spaces, yet materials, colours, and furnishings - often chosen later - can significantly impact indoor daylighting. This study assessed these effects in a typical open-plan office in Copenhagen using parametric simulations with Radiance through Honeybee in Grasshopper, complemented by a sensitivity analysis following the Morris method. Va
While grandiose narcissism is well-studied, vulnerable narcissism remains largely unexplored in the workplace context. Our study aimed to compare grandiose and vulnerable narcissism among managers and people from the general population. Within the managerial sample, our objective was to examine how these traits diverge concerning core personality traits and socially desirable responses. Furthermor
Purpose: This study aimed to assess the accuracy of patient-specific absorbed dose calculations for tumours and organs at risk in radiopharmaceutical therapy planning, utilizing hybrid planar-SPECT/CT imaging. Methods: Three Monte Carlo (MC) simulated digital patient phantoms were created, with time-activity data for mIBG labelled to I-123 (LEHR and ME collimators) and I-131 (HE collimator). The s
