Uncovering the role of PUS10 and RNA pseudouridylation in somatic cell reprogramming and cell fate determination
Uncovering the role of PUS10 and RNA pseudouridylation in somatic cell reprogramming and cell fate determination RNA modifications are emerging as dynamic regulators of gene expression programmes in development and disease. The isomerisation of uridine to pseudouridine (Ψ) is the most widespread modification in living organisms. Previously thought to be a static RNA mark, Ψ is currently known to