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Abstract Introduction: this study is about optimization and application of a new liquid chromatography tandem mass spectrometry method with reversed phase instead of HILIC column for analysis of methylmalonate. Background: methylmalonate cannot be broken down if there is a low level of cobalamin. Therefore, the investigation of lack of cobalamin is supplemented with, among other things, methyl
Ever since the Great Recession in 2008, the effectiveness of monetary policy has been increasingly debated. Central banks in modern economies were forced to find new ways of conducting expansionary monetary policy beyond conventional methods, most notably through quantitative easing and forward guidance, as they were at, or very close to, the zero lower bound of nominal interest rates. However, ev
In an evermore competitive environment for companies and business, predictive customer behaviour models can give companies a competitive edge over its competitors. Two such important predictive behaviour models are customer churn models and customer lifetime value (CLV) models. As it is more expensive for companies to acquire new customers rather than retaining existing ones, it is important for b
The recent revolution in structural prediction methods has made modeling novel protein structures a feasible analysis method. In particular, the Alphafold protocol can produce accurate models with atomic resolution. This work aims to model multiple novel toxin-antitoxin systems and to understand the interactions of their components through structural prediction and interface analysis. Structural p
Recruitment of new individuals is essential for a population to survive and flourish and bladderwrack (Fucus vesiculosus) is on the decline in some parts of the Baltic Sea. The causes being multitude and complex, culminating to the loss of light penetration being the main culprit. As society moves forward, artificial submerged structures may serve as new footholds for a waning population as well a
Disposable hygiene products, such as gloves and aprons, are commonly and frequently used in healthcare environments and are essential to maintain the hygiene standard. They are placed in different types of carriers, primarily in examination rooms and are mounted on the walls. This creates some difficulties for product development and fast access because not all hygiene products fit all carriers an
I samarbete med Cadence har detta examensarbete skapat ett webbaserat gränssnitt vilket kommer att visualisera stora mängder data på ett mer läsbart sätt för människor. Cadence är ett företag med inriktning på elektronisk system design och erbjuder andra företag lösningar för silikon design skapande, simulation, implementation och signoff för analoga och digitala kretsar och mycket mer. Detta gränIn collaboration with Cadence this thesis work has created a web based interface which aims to visualise large sets of data in a more human readable way. Cadence is a company specialising in electronic system design and is offering other companies solutions for silicon design creation, simulation, implementation and signoff of analog and digital circuits and a lot more. This interface will also be
The Swedish welfare system has been subject to extensive research, because of its unique alloy of capitalist and socialist ideas and principles. The Social Democratic formulation of the idea of the people’s home has been an integral part of the Swedish political discourse for the better part of a century. During the 1980’s and 1990’s, the hegemony of the social democratic ideology came into questi
Critical infrastructure is essential for a functioning society because of the services and goods they provide. Within these infrastructures there are several departments whose functionality is critical to society and when exposed to stress can lead to societal consequences. Therefore, it is important for the department within the critical infrastructure to have a solid crisis and continuity prepar
Gamification uses elements of game-designing on mundane tasks to enhance motivation and performance. This study aimed to investigate the effects of gamification on performance, intrinsic motivation and amotivation while doing work tasks. Using a randomized experimental design with the game design elements reward badges and character choice, gamification of in-tray exercises commonly used in Assess
I denna studie utforskar jag mitt intresseområde vilket är pianoundervisning inom den klassiska musikgenren på ett mer ingående sätt. Syftet med denna studie var att undersöka hur fem pianolärare, verksamma i fyra olika länder, strukturerar sina pianolektioner. Studiens fokus låg på grundskolor inom musik med klassisk inriktning. Det är en fördjupad studie i vad det egentligen innebär att undervis
The study of heterogeneous catalysis, especially within methane oxidation, is of high importance in order to more efficiently remove unburned methane from bio-fuel exhausts. This is relevant as bio-fuel engines will replace those driven by fossil fuels in the coming decades. This thesis contributes to the understanding of that reaction in a 5 mbar environmental pressure regime over a polycrystalli
With the growing global demand for affordable housing, the housing deficit needs to be addressed with building solutions that are fast to build while less expensive to operate and construct. As most prefabricated systems are targeted to mess production, individuality and option for customization has become highly limited. Looking into what is currently available in the market, reviewing these off
This master thesis project applies a mixed methods approach to fulfill the purpose of exploring how and in what ways digitalization transforms different retail categories. A theoretical framework is formulated using existing theories and research, from which four key variables are identified: distribution, interaction, competition and product offering. These variables, combined with an overarching
In the fall of 2022, Sweden's most significant social service that is located in Malmö City went through a major organizational change. The goal of the reorganization was that it would be easier to manage the daily operations, collaborate internally, and primarily handle cases equally when the respective departments were located in the same buildings. The aim of this study is to gain the persp
Both during and after the pandemic, the trend of biophilic design has reached maximum acceleration. One of the consequences being an increasing interest in gardening and plant care in general. Though not everybody might have so called ‘green fingers’, everyone should have the opportunity to try, and a product that facilitates horticulture is the self watering planter. IKEA of Sweden is looking int
Parkinson’s disease (PD) is a neurodegenerative disorder with toxic forms of alpha synuclein (α-syn) accumulating in the midbrain dopaminergic (DA) neurons, leading to cell death. In the first part of the study we wanted to investigate the midbrain DA population and their gene expression relative to the intracellular α-syn load. To this end, human wildtype α-syn was packaged inside custom, uniquel
