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Intuitionistic epistemic logic, Kripke models and Fitch's paradox
The present work is motivated by two questions. (1) What should an intuitionistic epistemic logic look like? (2) How should one interpret the knowledge operator in a Kripke-model for it? In what follows we outline an answer to (2) and give a model-theoretic definition of the operator $K$. This will shed some light also on (1), since it turns out that $K$, defined as we do, fulfills the properties
Flow field-flow fractionation: Critical overview.
This overview regards some critical issues in performing flow field-flow fractionation (flow FFF, FlFFF, AF4, HF-FlFFF, HF5). It includes the channel thickness, void time, channel-flow parabolic profile, channel-flow velocity gradient, uniformity of the cross-flow, sample injection time, relaxation/focusing time, width of sample starting zone, retention level, theoretical and experimental zone bro
Understanding quantitative structure-property relationships uncertainty in environmental fate modeling
In cases in which experimental data on chemical-specific input parameters are lacking, chemical regulations allow the use of alternatives to testing, such as in silico predictions based on quantitative structureproperty relationships (QSPRs). Such predictions are often given as point estimates; however, little is known about the extent to which uncertainties associated with QSPR predictions contri
Protein adsorption and complement activation for di-block copolymer nanoparticles
Four types of nanoparticles with core-diffuse shell structures have been synthesized through self-assembly of PICBA-Dextran block copolymers. These nanoparticles are designed to carry pharmaceutically active molecules into the human body through injection into the blood stream. In this work, we have determined how the characteristics of the diffuse shell influence the adsorption of three types of
Electron spectroscopic studies of nanowires formed by (GaMn)As growth on GaAs(111)B
Valence band photoemission with photon energies around the Mn2p excitation threshold has been used to study the development of nanowires catalyzed by MnAs particles. A gradual change in the spectra with increasing nanowire length is observed, such that the resonant photoemission eventually dominates over the Auger decay channel. The change is ascribed to dilution of Mn, showing that Mn is transfer
Search for New Particles in Two-Jet Final States in 7 TeV Proton-Proton Collisions with the ATLAS Detector at the LHC
A search for new heavy particles manifested as resonances in two-jet final states is presented. The data were produced in 7 TeV proton-proton collisions by the LHC and correspond to an integrated luminosity of 315 nb(-1) collected by the ATLAS detector. No resonances were observed. Upper limits were set on the product of cross section and signal acceptance for excited-quark (q*) production as a fu
Multicenter Patch Testing With a Resol Resin Based on Phenol and Formaldehyde Within the International Contact Dermatitis Research Group.
Contact allergy to phenol-formaldehyde resins (PFRs) based on phenol and formaldehyde is not detected by a p-tertiary-butylphenol-formaldehyde resin included in most baseline patch test series.
Medication beliefs and self-reported adherence-results of a pharmacist's consultation: a pilot study
Objectives Clinical outcomes in the secondary prevention of cardiovascular disease depend on the patients' adherence to prescribed medicines. Motivational interviewing (MI) is a patient-centred approach used to change different health behaviours. The objective of this pilot study was to explore the impact of a clinical pharmacist's consultation on beliefs about medicines and self-reported medicati
A GH57 4-α-glucanotransferase of hyperthermophilic origin with potential for alkyl glycoside production.
4-α-Glucanotransferase (GTase) enzymes (EC 2.4.1.25) modulate the size of α-glucans by cleaving and reforming α-1,4 glycosidic bonds in α-glucans, an essential process in starch and glycogen metabolism in plants and microorganisms. The glycoside hydrolase family 57 enzyme (GTase57) studied in the current work catalyzes both disproportionation and cyclization reactions. Amylose was converted into c
Effect of Everolimus Introduction and Calcineurin Inhibitor Reduction on Graft Vasculopathy in Heart Transplant Recipients
Efficient but getting wet feet. A not-entirely-frivolous note on the side-effects of growth-promoting institutions
Using data covering 38 countries across the 1965–2005 period, this paper shows that former British colonies tend to exhibit higher levels of carbon dioxide emission than other countries.
Myocardial Metabolism and Function During Induced Endotoxaemia and Hemorrhagic Shock in a Porcine Model
Humanistic and normativistic metaphysics, epistemology, and conative orientation: Two fundamental systems of meaning
Polarity Theory suggests that worldview controversies spanning areas such as morality, politics, epistemology, and metaphysics are ultimately rooted in the clash between humanism, which portrays human nature as intrinsically good and valuable, and normativism, which portrays human goodness and value as contingent upon conformity and achievement. Previous research has shown that humanism and normat
Combined effects of global change pressures on animal-mediated pollination
Pollination is an essential process in the sexual reproduction of seed plants and a key ecosystem service to human welfare. Animal pollinators decline as a consequence of five major global change pressures: climate change, landscape alteration, agricultural intensification, non-native species, and spread of pathogens. These pressures, which differ in their biotic or abiotic nature and their spatio
Nonmedical Prescription Drug Use (NMPDU) in the Swedish General Population-Correlates of Analgesic and Sedative Use.
Background: Nonmedical prescription drug use (NMPDU) is a growing problem in many countries. Objectives: The aim of the present study was to report correlates of and compare different subtypes of NMPDU in the Swedish general population. Methods: Data were drawn from a Swedish national household survey conducted in 2008-2009. A stratified sample of 58,000 individuals aged 15 to 64 was randomly sele
Arsenic trioxide is a novel agent for combination therapy to prolong heart allograft survival in allo-primed T cells transferred mice
Alloreactive memory T cells are major barriers to transplantation acceptance due to their capacity to accelerate rejection. Here, we investigated the effects of combined treatment with arsenic trioxide (As(2)O(3)) and blocking monoclonal antibodies (mAb) against CD154 and LFA-1 (anti-CD154/LFA-1) on graft survival as well as changes in pathology and immunological responses in mice with adoptively
Deriving seasonal dynamics in ecosystem properties of semi-arid savanna grasslands from in situ-based hyperspectral reflectance
This paper investigates how hyperspectral reflectance (between 350 and 1800 nm) can be used to infer ecosystem properties for a semi-arid savanna grassland in West Africa using a unique in situ-based multi-angular data set of hemispherical conical reflectance factor (HCRF) measurements. Relationships between seasonal dynamics in hyperspectral HCRF and ecosystem properties (biomass, gross primary p
Human Embryonic Stem Cell Derived Mesenchymal Stroma Cells (hES-MSC) Share Basic Properties with Bone Marrow MSC, They Have Potent Stroma Support Capacities but Lack Immune Modulatory Function Implications for off the Shelf ES MSC Therapies
Low-complexity detection of atrial fibrillation in continuous long-term monitoring.
This study describes an atrial fibrillation (AF) detector whose structure is well-adapted both for detection of subclinical AF episodes and for implementation in a battery-powered device for use in continuous long-term monitoring applications. A key aspect for achieving these two properties is the use of an 8-beat sliding window, which thus is much shorter than the 128-beat window used in most exi