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We examined the epidermal gene expression during the proliferative phase of wound healing. Matrix metalloproteases were the group of proteases most prominently up-regulated in skin wounds, whereas serine protease inhibitors were the most strongly up-regulated protease inhibitors. Furthermore, we found down-regulation of genes involved in the extrinsic pathway of apoptosis. This together with the u
Hyperalphalipoproteinemia, as observed in patients who are either homozygous or heterozygous for cholesteryl ester transfer protein (CETP) deficiency, has been shown to be associated with striking changes in apolipoprotein size distribution, namely, of high-density lipoprotein (HDL) and HDL-like particles. We compared the effect of varying degrees of CETP activity on the HDL apolipoprotein profile
Co-flowering plant species commonly share flower visitors, and thus have the potential to influence each other's pollination. In this study we analysed 750 quantitative plant-pollinator networks from 28 studies representing diverse biomes worldwide. We show that the potential for one plant species to influence another indirectly via shared pollinators was greater for plants whose resources were mo
Objective. To describe vascular events during an 8-year followup in a multicenter systemic lupus erythematosus (SLE) inception cohort and their attribution to atherosclerosis. Methods. Clinical data, including comorbidities, were recorded yearly. Vascular events were recorded and attributed to atherosclerosis or not. All of the events met standard clinical criteria. Factors associated with atheros
Fox Sparrows (Passerella iliaca (Merrem, 1786)) and Song Sparrows (Melospiza melodia (A. Wilson, 1810)) cohabit on many islands along the Pacific coast of North America, and previous studies suggest that they rely on similar prey types. We used delta C-13 and delta N-15 stable isotope analysis on blood collected from breeding adults of both species in each of two habitats on Triangle Island, Briti
Case studies are largely used for investigating software engineering practices. They are characterized by their flexible nature, multiple forms of data collection, and are mostly informed by qualitative data. Synthesis of case studies is necessary to build a body of knowledge from individual cases. There are many methods for such synthesis, but they are yet not well explored in software engineerin
To specify the incidence and risk factors for secondary autoimmune diseases (ADs) after HSCT for a primary AD, we retrospectively analyzed AD patients treated by HSCT reported to EBMT from 1995 to 2009 with at least 1 secondary AD (cases) and those without (controls). After autologous HSCT, 29 of 347 patients developed at least 1 secondary AD within 21.9 (0.6-49) months and after allogeneic HSCT,
Background Children with poor response acute myeloid leukaemia (AML) generally have a very poor outcome. Allogeneic stem cell transplantation (SCT) is often recommended for these children but the benefit is unclear. The aim of this study was to investigate survival for poor response AML patients treated with SCT. Material and Methods Treatment was given according to the NOPHO-AML 2004 protocol. Al
A cervical cytology biobank (CCB) is an extension of current cytopathology laboratory practice consisting in the systematic storage of Pap smears or liquid-based cytology samples from women participating in cervical cancer screening with the explicit purpose to facilitate future scientific research and quality audit of preventive services. A CCB should use an internationally agreed uniform cytolog
Functionalresponses describe the per capita consumption rates of predators depending on prey density, which quantifies the energy transfer between trophic levels. We studied a typical interaction of the litter–soil systems between hunting spiders (Pardosa lugubris; Araneae: Lycosidae) and springtails (Heteromurus nitidus; Collembola: Entomobryidae) at varying habitatstructure, i.e. with moss vs. w
Changing fire regimes in response to climate change are likely to have significant effects on terrestrial ecosystems and biogeochemical cycles. While effects of fire on some nutrient cycles have been quite well-studied, little attention has been paid to the silicon cycle. We used an alkaline continuous extraction to examine changes in the quantity and characteristics of alkaline extractable Si (Al
Objective: To study the effect of a large number of repetitions on the most comfortable level (MCL) when doing the acceptable noise level (ANL) test, and explore if MCL variability is related to central cognitive processes. Design: Twelve MCL repetitions were measured within the ANL test using interleaved methodology during one session using a non-semantic version. Phonological (PWM) and visuospat
Factor H is an important complement regulator of the alternative pathway commonly recruited by pathogens for increased survival in the human host. The respiratory pathogen Moraxella catarrhalis that resides in the mucosa is highly serum resistant and causes otitis media in children and respiratory tract infections in individuals with underlying diseases. In this study, we show that M. catarrhalis
We present a method based on passive spectroscopy with aim to remotely study flying birds. A compact spectrometer is continuously recording spectra of a small section of the sky, waiting for birds to obscure part of the field-of-view when they pass the field in flight. In such situations the total light intensity received through the telescope, looking straight up, will change very rapidly as comp
So far, no common environmental and/or phenotypic factor has been associated with melanoma and renal cell carcinoma (RCC). The known risk factors for melanoma include sun exposure, pigmentation and nevus phenotypes(1); risk factors associated with RCC include smoking, obesity and hypertension(2). A recent study of coexisting melanoma and RCC in the same patients supports a genetic predisposition u
Local irritation and inflammation at the site of administration is a common side effect following administration of parenteral formulations. Biological effects of surface (interfacial) activity in solutions are less well investigated than effects caused by other physico-chemical parameters such as pH and osmolality. The interfacial activity in different systems, including human plasma, typical amp
We present here a dynamical method for modelling temporal and geographical variations in ammonia emissions in regional-scale chemistry transport models (CTMs) and chemistry climate models (CCMs). The method is based on the meteorology in the models and gridded inventories. We use the dynamical method to investigate the spatiotemporal variability of ammonia emissions across part of Europe and study
This article presents an analysis of football supporters as magicians based on the theory of magic developed by Marcel Mauss. The research was conducted in co-operation with a local football club from Sweden called Malmö FF. Taking into consideration how the supporters see their position in the club and their contribution, it is possible to explain their behaviour and involvement in terms of a col
The imprinting factors of the β-lactam antibiotics penicillin V, methicillin, nafcillin, oxacillin, cloxacillin, dicloxacillin, and piperacillin on a poly(methacrylic acid-co-trimethylolpropane trimethacrylate) molecularly imprinted stationary phase targeted for penicillin G were correlated with molecular descriptors obtained by molecular computation. One-parameter linear regression and multivaria
Femoral neck fractures in children and young adults are rare, but have a high risk of avascular necrosis (AVN) and subsequent gradual collapse of the femoral head. In 2006, we initiated the use of scintigraphy for the diagnosis of vascular impairment after a cervical fracture in children. In the present retrospective case study, we evaluated the effect of the remaining postoperative circulation in
