Filtyp
ADP-ribosylation is a conserved modification that uses NAD+ as a co-substrate to regulate essential cellular processes, such as genome stability and transcription, with Poly(ADP-ribose) Polymerases (PARPs) serving as the major catalyzing enzymes in humans. Historically defined as a protein post-translational modification, ADP-ribosylation on nucleic acids has been increasingly recognized in recent
In this paper, in-situ X-ray microtomography was used to analyze liquor penetration/impregnation and delignification of wood chips during kraft pulping, allowing microstructural changes to be assessed over time. The study was conducted with sapwood of three hardwood species (alder, aspen and birch), using a reactor designed to provide liquor circulation and temperature control. Each wood sample wa
Al-Ga-based alloys are promising carriers of renewable energy, which can provide hydrogen by hydrolysis in challenging working environments. Manipulating their performance by different process conditions and comprehending the mechanisms are important for achieving directional design synthesis of alloys and enhancing their practicality. This study presents a novel approach to optimizing the hydroge
Droughts have intensified under climate change, threatening ecosystem stability. While rising atmospheric CO2 concentrations may enhance vegetation drought resistance, the net effect remains uncertain amid concurrent warming. Here we combine ecological modeling with multi-source observations to investigate how CO2 and warming jointly regulate vegetation drought responses on the Qinghai-Tibetan Pla
Background: Tick-borne encephalitis (TBE) is a serious vector-borne neurological disease in Europe, with a complex transmission cycle involving ticks of genus Ixodes, animal hosts, environmental and climatic determinants. Methods: We modelled annual Geocoded Swedish TBE case data for the period 2005–2023 as a log-Gaussian Cox process in relation to population, environmental and climate data, and w
Background: The C-reactive protein-triglyceride-glucose index (CTI) has been proposed as a novel biomarker for insulin resistance and inflammation. However, its role in the progression trajectory of cardiometabolic multimorbidity (CMM) remains unclear. We aimed to investigate the involvement of the CTI in the CMM progression trajectory. Methods: This prospective study included 266,049 individuals
This article examines how de-risking policy instruments interact to shape implementation conditions for Sino-research collaboration in Danish, Norwegian and Swedish higher education institutions (HEIs). Using comparative policy analysis, it analyses how instruments combine across types, functions and actor loci, and what these interactions mean for HEIs. The findings show that implementation condi
The interest in putting a price on carbon emissions is increasing in pace with the urgency of climate change. In this article we compare the adoption of one such policy instrument, carbon taxation, in the cases of Sweden and Mexico. We use a theoretical framework that focuses on economic and environmental factors influencing the policy process via distinct policy areas, as well as the mechanisms t
AbstractThe need to minimise wear of hardmetal cutting tool materials requires an understanding of, and in turn accurate measurement of, both the external changes in dimensions and the internal microstructural changes which cause plastic deformation underneath the tool coating.This paper summarises development of methods to quantify the dimensional changes of the complex 3D tip shape of a tool and
All-solid-state batteries provide new hope for developing electrical energy storage far beyond the current state of the art. Here, we present a new sample environment developed for operando and in situ investigations of solid-state batteries, allowing for simultaneous collection of X-ray diffraction and electrochemical data along with temperature control and stack pressure monitoring. The Aarhus p
Background: Continuous traits evolution of a group of taxa that are correlated through a phylogenetic tree is commonly modelled using parametric stochastic differential equations to represent deterministic change of traits through time, while incorporating noises that represent different unobservable evolutionary pressures. A heterogeneous Gaussian process that consists of multiple parametric sub-
Soluble growth stimulation protein form of interleukin-1 receptor-like 1 (ST2) may signal myocardial stress, and elevated ST2 blood levels are associated with adverse outcomes in adult heart disease. Data on ST2 in children with congenital heart disease (CHD) is limited. This study explored ST2 in newborns and older children with atrial septal defect (ASD), as this represents a common CHD type tha
Anxiety and mood disorders are the most diagnosed mental health conditions globally, but many people do not have access to treatment that is effective, affordable, and acceptable. Sensory modulation intervention is an emerging approach, which may provide an accessible alternative or complement to existing pharmaceutical and talking therapies for managing anxiety and low mood. Evidence suggests tha
The α-transfer and breakup channels in7Be+12C at 35 MeV are studied. The total cross sections from α-transfer, populating different states of16O are obtained. This work also presents the first exclusive breakup measurement of7Be. In contrast to earlier works, the results show a significant contribution of breakup.
A set of ultrawide bandgap single-crystal NdGaO3 samples cut with crystallographic surface orientations (001), (101), and (110) are investigated by using generalized spectroscopic ellipsometry. We report the complex anisotropic dielectric functions in the spectral range from 0.73 to 9.0 eV, for polarization along directions a, b, and c of the orthorhombic unit cell. A Kramers–Kronig consistent par
Synthetic biomaterials used as bone graft extenders (BGE) in spinal fusion surgery can supplement but do not replace autologous bone. This pilot study evaluated a calcium sulfate/hydroxyapatite (CaS/HA) material as an antibiotic-eluting BGE and a carrier for bone morphogenetic protein-2 (BMP-2) in a rabbit posterolateral lumbar (L4–L5) spinal fusion model (PLF). Pre-set CaS/HA beads were loaded wi
