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The differential diagnosis between Type 1 (insulin-dependent) and Type 2 (non-insulin-dependent) diabetes is complicated since no specific markers are available for either disease. In this study, 244 consecutive patients were diagnosed with diabetes mellitus during two years in Malmö (230000 inhabitants), corresponding to an incidence rate of 53·100000-1·year-1. Age, body mass index, HbA1c, C-pept

The effect of immunizing healthy individuals with either tetanus toxoid or yellow fever live attenuated vaccine was examined by measuring interferon (IFN)-dependent oligoadenylate synthetase (2-5A) activity. This enzyme converts ATP into oligonucleotides coupled together in 2'-5' diester bonds. The synthetized products possess among other effects growth inhibiting properties and stimulate a latent

Dithizone, a zinc chelating agent, is known to selectively stain the islets of Langerhans in the pancreas. In the present study, we have used this stain to aid the identification of islets in material obtained by collagenase digestion of human pancreas. Islets were shown to rapidly and reversibly stain red on incubation with dithizone solution. Tissue selected on the basis of dithizone staining wa

The idiom ‘for someone’s sake’ plays a central role in recent attempts to understand the distinction between impersonal values and personal values—e.g. between what is valuable or good, period, and what is valuable for or good for someone. In the first section three historical approaches to this distinction are outlined. Section 2 presents a modified fitting-attitude (FA) analysis of final ‘value-

Vision sensors are built from a camera and intelligent hardware and/or software. Steadily decreasing microelectronic costs have spawned a large number of vision sensory applications, such as surface defect detection. A constructive method for defect detection entails a mixture of mathematical and intelligent modules. Such a heterogeneous modular system can be realized in many ways. In this paper w

Popular Abstract in Swedish Genteknik innebär stora möjligheter att förändra och förbättra organismers egenskaper. Genom att i en organism föra in en främmande gen kan man ge den helt nya egenskaper som den aldrig skulle ha förvärvat på naturlig väg. Genmodifierade bakterier odlas idag industriellt i stora bioreaktorer för tillverkning av olika proteiner, till exempel insulin till diabetiker, humaVitreoscilla is an obligate aerobic bacterium living in oxygen-poor environments such as stagnant ponds and decaying vegetable matter. Vitreoscilla expresses a homodimeric haemoglobin (VHb) when subjected to oxygen-limited conditions. In several organisms, expression of VHb has been shown to increase microaerobic cell growth and enhance oxygen-dependent cell metabolism. Moreover, the presence of V