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Variability in reported histopathology parameters in operated periampullary adenocarcinomas may affect the prognostic weight of the parameters. Standardized axial sectioning produces a higher incidence of involved margins and also seems to produce a lower relative incidence of pancreatic compared with distal bile duct origin and a higher incidence of involved lymph nodes, compared with non-standar
We present calculations of fission properties for heavy elements. The calculations are based on the macroscopic-microscopic finite-range liquid-drop model with a 2002 parameter set. For each nucleus we have calculated the potential energy in three different shape parametrizations: (1) for 5 009 325 different shapes in a five-dimensional deformation space given by the three-quadratic-surface parame
Measurements of the centrality and rapidity dependence of inclusive jet production in root(NN)-N-S = 5.02 TeV proton-lead (p + Pb) collisions and the jet cross-section in root s = 2.76 TeV proton-proton collisions are presented. These quantities are measured in datasets corresponding to an integrated luminosity of 27.8 nb(-1) and 4.0 pb(-1), respectively, recorded with the ATLAS detector at the La
We present a theoretical investigation of the hyperfine structure of the 5s5d D-3(2)-5s4f F-3(2,3)0 transitions in In II. Earlier work has failed in determining hyperfine constants for the upper levels of these transitions. We show that this is due to strong off-diagonal hyperfine interaction, which not only changes the position of the individual hyperfine lines but also introduces large intensity
Enzymatic pretreatment of algae by means of cellulose degrading enzyme was evaluated through lab-scale and pilot-scale experiments. The degradation efficiency of the enzyme depended on the initial physical quality of the algae. Lab-scale batch anaerobic digestion experiments showed comparatively low methane potential for the pretreated algae at both mesophilic and thermophilic temperatures. Howeve
Various researchers and policy analysts have made empirical studies of innovation systems in order to understand their current structure and trace their dynamics. However, policy makers often experience difficulties in extracting practical guidelines from studies of this kind. In this paper, we operationalize our previous work on a functional approach to analyzing innovation system dynamics into a
Disposable electrodes were fabricated by coating chromium (5 nm) and gold (200 nm) on glass strips (5.0 mm x 25.4 mm) and used in a label-free immunosensor. Human Serum albumin (HSA) and its antigen (anti-HSA) were used as a model system. Electropolymerization of o-phenylenediamine was used for the immobilization of anti-HSA by covalent binding. A linear relationship was obtained in the range from
Popular Abstract in Swedish Det finns celler i vår kropp som har ett livslångt ansvar att tillverka alla blodceller. De kallas blodstamceller, eller hematopoetiska stamceller, och är en till antalet liten population celler som har den enorma kapaciteten att göra 1012 blodceller om dagen under hela vårt liv. Blodstamceller har multipotentiell differentieringsförmåga dvs. de kan bilda alla mogna bloThis thesis is about the regulation of hematopoietic stem cells (HSCs) that represent rare cells residing in the bone marrow (BM) of adults. They are multipotent cells that have the capacity to differentiate to all mature cells of the blood system and have the capacity to self-renew, i.e. generate new HSCs. These cells have tremendous therapeutic potential to treat a variety of hematopoietic disor
Introduction: Interatrial frequency gradient is used to guide catheter ablation of atrial fibrillation (AF) but reliable tools for its non-invasive estimation are lacking. We present a patient with dissociated left and right atrial rhythms that allows identification of sum face ECG leads that closely reflect left atrial activity. Methods: 12-lead ECG was recorded simultaneously with electrograms f
BACKGROUND: The requirement of essential fatty acids (EFA) for the development of the brain is well documented. OBJECTIVE: To investigate the early neurological development at term and 44weeks gestational age in preterm infants in relation to EFA concentrations in breast milk and in infants' and mothers' plasma phospholipids. METHOD: Fifty-one premature infants and their mothers were consecutively
Background: The widespread use of relative scales in socioepidemiological studies has recently been criticized. The criticism is based mainly on the fact that the importance of different risk factors in explaining social inequalities in cardiovascular disease (CVD) varies, depending on which scale is used to measure social inequalities. The present study examines the importance of established risk
Mammalian cells, including tumor cells, adapt to hypoxia via stabilization of two transcription factors - Hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha. Among other consequences, hypoxia is a main driving force behind angiogenesis. The differentiation stage of tumor cells is recognized as an important clinical factor in several malignancies including neuroblastoma. Tumors with an immature
Federmann, R., Bäckström, M. & Goldsmith, R. (2009). The Stress Strategy Test in relation to personality traits and cognitive abilities. Scandinavian Journal of Psychology.Relations between results of the Stress Strategy Test (SST), a computerized test the first author developed partly involving the Stroop effect, and of an interview and an intelligence test used by the Swedish armed forces as
Mating systems and parental care are predicted to coevolve because the former dictates the cost-benefit ratio of the latter by affecting genetic relatedness between adults and offspring. Reptiles show only rudimentary forms of sociality and parental care and, hence, could provide important insights into the early stages of the evolution and maintenance of social systems. The skink genus Egernia ex
Between 1992 and 2008, 713 high hyperdiploid acute lymphoblastic leukemias in children aged 1-15 years were diagnosed and treated according to the Nordic Society for Pediatric Hematology and Oncology acute lymphoblastic leukemia 1992/2000 protocols. Twenty (2.8%) harbored t(1;19), t(9; 22), der(11q23), or t(12; 21). The median age of patients with "classic" high hyperdiploidy was lower than that o
Neutrophils interacting with a chemoattractant gradually become nonresponsive to further stimulation by the same agonist, a process known as desensitization. Receptor desensitization is a highly regulated process that involves different mechanisms depending on which receptor-ligand pair that is studied. Galectin-3, a member of a large family of beta-galactoside-binding lectins, has been suggested
A central question in Alzheimer's disease (AD) research is what role β-amyloid peptide (Aβ) plays in synaptic dysfunction. Synaptic activity increases Aβ secretion, potentially inhibiting synapses, but also decreases intraneuronal Aβ, protecting synapses. We now show that levels of secreted Aβ fall with time in culture in neurons of AD-transgenic mice, but not wild-type mice. Moreover, the ability
In Sweden, a large share of public services are organised, produced and delivered by municipalities, large and small, rich and poor. Contextual conditions (size and location) and economic conditions (efficiency and wealth) differ considerably among these service-providing organisations. The question raised in this paper is whether a municipality's economic situation is a direct consequence of the
Objective. To study lumbopelvic pain in women randomized to a regular exercise program during pregnancy in comparison to women receiving standard antenatal care. Design. A two-armed, two-center, randomized controlled trial. Setting. St Olavs Hospital, Trondheim University Hospital and Stavanger University Hospital. Population. A total of 855 pregnant women were randomized to intervention or contro
