Filtyp
Objective: Intranasal immunization with a fusion protein of the ApoB100-derived peptide p210 and the cholera toxin B subunit (CTB-p210) has previously been shown to induce mucosal tolerance and reduce atherosclerosis development, but the exact mode of action remains to be elucidated. Recent studies have indicated an important role for B cells in mucosal tolerance, in particular by induction of reg
The objective of this paper is to evaluate the performance of a semi-closed oxy-fuel combustion combined cycle (SCOC-CC) and its power penalties. The power penalties are associated with CO2 compression and high-pressure oxygen production in the air separation unit (ASU). The paper discusses three different methods for high pressure oxygen (O2) production. Method 1 is producing O2 directly at high
Purpose: Magnetic resonance imaging (MRI)-only radiotherapy is performed without computed tomography (CT). A synthetic CT (sCT) is used for treatment planning. The aim of this study was to develop a clinically feasible quality assurance (QA) procedure for sCT using the kV-cone beam CT (CBCT), in an MRI-only workflow for prostate cancer patients. Material and method: Three criteria were addressed;
Today, glucagon-like peptide-1 (GLP-1) receptor agonists are established glucose-lowering drugs used in the management of type 2 diabetes. Their development emerged from the understanding that a combined islet dysfunction comprising of impaired insulin secretion and exaggerated glucagon secretion is the key defect of hyperglycemia. GLP-1 was shown to target these defects, and after the discovery t
Membrane technology is a relative new technology in the pulp and paper industry with interesting applications in the water loop, the by-product loop and the chemical loop. The technology was pioneered in the pulp and paper industry by DDS Filtration, now Alfa Laval Nakskov in the 1970’ies and this article reviews the opportunities to use membrane technology in the different loops investigated ove
Purpose: To characterize the effects of water T2 relaxation time in the glycosaminoglycan chemical exchange saturation transfer method (gagCEST) and compare them between 3T and 7T as well as between various saturation schemes. Methods: Simulations and a phantom experiment were conducted at 3T and 7T in a range of water T2 values and GAG concentrations using various saturation schemes. For both sim
Purpose: This study examines the influence of voice quality and multi-talker babble noise on processing and storage performance in a working memory task performed by children using cochlear implants (CI) and/or hearing aids (HA). Methods: Twenty-three children with a hearing impairment using CI and/or HA participated. Age range was between 6 and 13 years. The Competing Language Processing Task (CL
Active design is an expression that has been used fore some years now. This paper will present a case study from an excavation of two cavern constructions (80m long x 16m wide x 12m high) and access tunnels in a Bryozoan limestone in southern Sweden. By using various geophysical survey methods like for instance resistivity soundings, in combination with core drilling and geophysical well logs a ge
This review discusses in vivo airway aspects of plasma exudation in relation to current views on epithelial permeability and epithelial regeneration in health and disease. Microvascular-epithelial exudation of bulk plasma proteins characteristically occurs in asthmatic patients, being especially pronounced in those with severe and exacerbating asthma. Healthy human and guinea pig airways challenge
Final value accrues to objects that are good for their own sakes, while instrumental value accrues to objects that are good for the sake of their effects. The following paper aims to show that this distinction cuts across some surprising areas of the evaluative domain. This means that there may be some unexpected types of value that can come in a final or instrumental form. The argument proceeds b
Helianthemum oelandicum var. oelandicum is an endemic taxon on the Baltic island of Öland, SE Sweden. Plants can be classified into two morphs: the bristled morph (with bristles and with or without scattered stellate hairs) and the glabrous morph (without bristles and stellate hairs). In crosses between plants assumed to be homozygous for the trait that characterises the phenotypes of the two morp
Arguments in favour of strengthening the rights of victim–survivors in the criminal justice process have largely been made within the framework of a human rights perspective and with a view to meeting their procedural needs and minimising their experiences of secondary victimisation. In this article, however, I ask whether the prevalent legal arrangement, whereby victim–survivors are assigned the
Heat supply bottlenecks are common in district heating (DH) networks and makes the DH network work in a non-optimal way, why it is beneficial to address them. The purpose of this paper is thus to investigate risks, opportunities, added values and issues coupled to various bottleneck measures. This is made by in depth interviews with DH companies and through DH network simulations. The results show
Most of the present scientific efforts and technical developments within water supply, water treatment technology, environmental protection and restoration methods are still devoted to technology designed by, and applicable in rich, developed countries. These technologies emerged in a long process of development during the last century, mainly in European countries and in North America. During thi
In this paper I take another look at the view, defended by C. Nino, that we may punish criminals because, by knowingly breaking a law, they have consented to becoming liable to the prescribed punishment. I will first rebut the criticisms usually aimed at this view in the literature, aiming to show that they are inconclusive. They are all efforts to show that criminal offenders in fact do not conse
We have estimated free energies for the binding of eight carboxylate ligands to two variants of the octa-acid deep-cavity host in the SAMPL6 blind-test challenge (with or without endo methyl groups on the four upper-rim benzoate groups, OAM and OAH, respectively). We employed free-energy perturbation (FEP) for relative binding energies at the molecular mechanics (MM) and the combined quantum mecha
This study concerns effects of two main variables on hydrodynamics and mass transfer in the liquid-liquid two-phase slug flow regime. The influence of size of square and rectangular microchannels and presence of sodium dodecyl sulfate (SDS) are investigated. Three microchannels with dimensions 600x600 (MC600), 400x400 (MC400) and 600x300 (MC300) µm were used with hydraulic diameters of 600, 400 an
