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Obesity and excess weight increase the risk of developing type 2 diabetes, but individuals of normal weight can also develop the disease. Researchers at Lund University in Sweden have discovered that it is possible to identify at-risk individuals by measuring BMI in a new way. The authors of the study have identified metabolic changes associated with obesity that can increase the risk of developin

https://www.medicine.lu.se/article/metabolic-bmi-can-predict-risk-type-2-diabetes-normal-weight-patients - 2026-10-17

At the end of March, the first cases of acute severe hepatitis of unknown origin in children were reported in the UK. Since then, the number has increased to more than 300 in around 20 countries; there are now reports of nine suspected cases in Sweden. The acute liver infection mainly affects otherwise completely healthy children under the age of 16, which puzzles researchers who are now searching

https://www.medicine.lu.se/article/researchers-search-answers-increase-acute-severe-hepatitis-children - 2026-10-17

Epigenetics has become an important tool for researchers endeavoring to understand the causes and development stages of type 2 diabetes. In the future, epigenetic biomarkers could be used to predict type 2 diabetes and individualise its treatment. Diabetes and epigenetics researchers at Lund University summarise some of the most important advancements in a review article published in Nature Review

https://www.medicine.lu.se/article/epigenetics-can-pave-way-individualised-treatment-type-2-diabetes - 2026-10-17

One in three patients is asked about their lifestyle habits when they visit the outpatient healthcare clinics. This figure really ought to be higher, according to Professors Hanne Tønnesen and Inger Kristensson Hallström, who are in charge of the WHO Collaborating Centre at Lund University. Lifestyle should concern the health care system even more than it does today,stresses Hanne Tønnesen: “We qu

https://www.medicine.lu.se/article/who-mission-creating-evidence-how-health-care-can-prevent-disease - 2026-10-17

In order to be able to prescribe the appropriate dose of physical activity to patients, healthcare professionals need to consider a range of individual factors. There is a need to facilitate the assessment of aerobic capacity i. e. maximal oxygen uptake capacity (VO2max), as well as to calculate the intensity of training according to the WHO recommendations for physical activity. Now, researchers

https://www.medicine.lu.se/article/my-aerobic-capacity-rpc - 2026-10-17

The Bundy Academy’s 2022 major prize amounting to SEK 3 million is awarded to Sebastian Palmqvist, Associate Professor of Clinical Memory Research at Lund University and Senior Physician at the Memory Clinic at Skåne University Hospital, for his research on improved diagnostics of Alzheimer’s disease. RationaleSebastian Palmqvist has published a large number of research papers in the field of cogn

https://www.medicine.lu.se/article/awardees-2022-bundy-academy-major-prize - 2026-10-17

By using cells isolated from cancer patients and mixing them with a new technology called “OssiGel”, it is possible to engineer human mini-bones. These miniaturized organs consist of mature bone and marrow tissue and can be used as model to study the disease mechanisms behind cancers that arise in bone marrow or spread to the bones, and offer the personalized testing of new drugs. Paul Bourgine is

https://www.medicine.lu.se/article/miniature-bones-research-model-cancer - 2026-10-17

Insulin secretion into the bloodstream requires a protein called CD59. New research led by Lund University shows that the two protein variants that are responsible for this function of CD59 are affected in diabetes. The study has been recently published in PNAS. Insulin affects many bodily functions, and is required for survival. It causes cells to take up glucose from the blood, storage of energy

https://www.medicine.lu.se/article/newly-discovered-protein-variants-are-key-insulin-secretion - 2026-10-17

Researchers at Lund University in Sweden have developed a new method for studying age-related brain disorders. The researchers have focused on the neurodegenerative disorder Huntington’s disease and the results have now been published in the journal Brain. Basic medical research often faces the challenge of developing disease models that correspond to specific disease mechanisms or the disease to

https://www.medicine.lu.se/article/researchers-reprogram-human-skin-cells-aged-neurons-study-neurodegenerative-disorders - 2026-10-17

The environment in which breast cancer arises –the interplay between the patient’s BMI, tumour size and cancer-specific proteins –is of importance for the prognosis. This is shown in a study from Lund University in Sweden. The knowledge could further enhance precision medicine in breast cancer. Major advances in diagnostics and treatment have improved survival rates among breast cancer patients in

https://www.medicine.lu.se/article/tumour-environment-can-affect-breast-cancer-prognosis - 2026-10-17

A large amount of lungs donated yearly cannot be used for transplantation. Researchers at Skåne University Hospital and Lund University have conducted an animal study with results that give hope that more donor lungs could be used to save lives in the future. The researchers have started a pilot study to investigate if the treatment will have the same positive effects on human beings. About 190 or

https://www.medicine.lu.se/article/new-treatment-can-result-access-more-donor-lungs-and-fewer-complications-after-transplantations - 2026-10-17

In November 2021, a private foundation was established to promote scientific research in pancreatic cancer, gastroenterology, and pain management at Lund University. The foundation will be endowed with a total of SEK 40 million and will be managed by Lund University. Earlier this spring, the first grants from the foundation were distributed – approx. SEK 3 million will support the efforts of five

https://www.medicine.lu.se/article/sek-40-million-donation-faculty-medicine - 2026-10-17

Den här artikeln är över 5 år gammal, och informationen kan därför vara inaktuell. På senare år har man upptäckt ett 70-tal genetiska riskvarianter för diabetes, men fortfarande är TCF7L2 - känd som ”diabetesgenen” - den gen som innebär störst risk för att insjukna i typ 2 diabetes. Med hjälp av en ny metod, ”exon skipping”, vill Ola Hansson vid Lunds universitets Diabetescentrum fördjupa kunskape

https://www.diabetesportalen.lu.se/artikel/ny-metod-reparerar-skadade-gener - 2026-10-17

Den här artikeln är över 5 år gammal, och informationen kan därför vara inaktuell. Med hjälp av ett enkelt blodprov kan man i dag se att vissa personer i framtiden riskerar att insjukna i typ 2 diabetes. Anders Rosengren, forskare vid Lunds universitets Diabetescentrum och läkare vid Skåne universitetssjukhus i Malmö, håller nu på att studera hur man kan hitta nya behandlingar för personer med en

https://www.diabetesportalen.lu.se/artikel/inflammationshammande-lakemedel-ska-forhindra-diabetes-typ-2 - 2026-10-17

Impaired insulin secretion is closely associated with type 2 diabetes, but the process is not yet fully understood. A new study by researchers at Lund University shows that the Piezo1 ion channel regulates insulin secretion, which means it may be an important target for new diabetes treatments. Type 2 diabetes often occurs because the pancreatic beta cells are unable to produce enough effective in

https://www.medicine.lu.se/article/study-shows-piezo1-ion-channel-plays-important-role-insulin-secretion - 2026-10-17

Den här artikeln är över 5 år gammal, och informationen kan därför vara inaktuell. Diamyd Medical, som äger diabetesvaccinet GAD, har slutit ett nytt licensavtal med University of California i Los Angeles. Avtalet avser ett patent på terapeutisk användning av GABA (gammaaminosmörsyra) i kombination med GAD vid typ 1-diabetes och andra inflammatoriska tillstånd som vid typ 2-diabetes, metabolt synd

https://www.diabetesportalen.lu.se/artikel/nytt-diabetesprojekt-diamyd - 2026-10-17

Den här artikeln är över 5 år gammal, och informationen kan därför vara inaktuell. Dendritcellen är en typ av cell som upptäcktes på 70-talet men nu blivit ett hett forskningsobjekt. Den spelar en viktig roll för immunförsvaret genom att plocka upp främmande ämnen och presentera dem för de vita blodkroppar som ska bekämpa angriparna. En forskargrupp från Lunds universitet har just publicerat en ar

https://www.diabetesportalen.lu.se/artikel/dendritcellerna-viktiga-var-tarmhalsa - 2026-10-17

Den här artikeln är över 5 år gammal, och informationen kan därför vara inaktuell. En av de huvudmisstänkta orsakerna till att processen mot autoimmunitet och typ 1 diabetes triggas igång har i många år varit virusinfektioner. En ny studie kunde dock inte bekräfta något samband. Två grupper av barn i TEDDY-undersökningen (se länkar nedan) har jämförts. Dels de som har utvecklat antikroppar vilka ä

https://www.diabetesportalen.lu.se/artikel/ny-teddy-studie-diabetesgatan-fortsatter-gacka-forskarna - 2026-10-17

Den här artikeln är över 5 år gammal, och informationen kan därför vara inaktuell. Forskare vid Lunds universitet har tillsammans med holländska kollegor använt en ny teknik som lett till förbättrad insulinproduktion i mänskliga celler. – Vår studie är ett första steg mot att använda konstgjorda molekyler, sk antagomirer som behandling vid typ 2-diabetes, säger Lena Eliasson, professor vid Lunds u

https://www.diabetesportalen.lu.se/artikel/antagomirer-ny-substans-vid-behandling-av-typ-2-diabetes - 2026-10-17

Den här artikeln är över 5 år gammal, och informationen kan därför vara inaktuell. Forskare vid Karolinska Institutet har identifierat en mekanism som kan förklara den försämrade sårläkningen vid diabetes, som kan leda till diabetiska fotsår. Studien publiceras i tidskriften PNAS, Proceedings of the National Academy of Sciences. Hos möss med diabetes förbättrades sårläkningen när den identifierade

https://www.diabetesportalen.lu.se/artikel/mekanism-bakom-forsamrad-sarlakning-vid-diabetes-identifierad - 2026-10-17