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Regulation of RNA splicing reveals unique clinical features of aggressive breast cancers

Researchers from Lund University in Sweden have identified a new layer of gene regulation mediated by changes in ribonucleic acid metabolism downstream of major oncogenes. This study, published now in the Molecular Cell journal, explains aggressive clinical features observed in triple negative breast cancers. A collaborative study between Lund Stem Cell Center (LSCC) and Lund University Cancer Cen

https://www.stemcellcenter.lu.se/article/regulation-rna-splicing-reveals-unique-clinical-features-aggressive-breast-cancers - 2025-12-04

PhD defence interview - Shelby Shrigley

During her PhD studies Shelby Shrigley has been exploring patient-specific cell replacement therapy for Parkinson's disease. Defending her PhD thesis on March 12th, here Shelby tells us about her research within the Developmental and Regenerative Neurobiology research group led by Prof. Malin Parmar and her time spent at Lund Stem Cell Center. Can you tell us about your PhD research? The main focu

https://www.stemcellcenter.lu.se/article/phd-defence-interview-shelby-shrigley - 2025-12-04

New method for developing antibody-based drugs

In recent years, therapeutic antibodies have transformed the treatment of cancer and autoimmune diseases. Now, researchers at Lund University in Sweden have developed a new, efficient method based on the genetic scissors CRISPR-Cas9, that facilitates antibody development. The discovery is published in Nature Communications. Antibody drugs are the fastest growing class of drug, and several therapeu

https://www.stemcellcenter.lu.se/article/new-method-developing-antibody-based-drugs - 2025-12-04

New model of human airways speeds up the battle against Covid-19

The fight against COVID-19 continues. In Lund, researchers are working to identify a compound that could be used to prevent viral infection, and thus save lives. “This model that has been developed with our collaborators will fill an important gap for current and future drug screening efforts for the upper or lower airways using human airway cells”, says Sinem Tas, associate researcher. The most r

https://www.stemcellcenter.lu.se/article/new-model-human-airways-speeds-battle-against-covid-19 - 2025-12-04