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New research shows that it is possible to induce new bone formation around orthopaedic implants in osteoporotic patients. The study has been published in Acta Biomaterialia. The study, which was led from Lund University in Sweden, is a collaboration with researchers from Lithuania, Germany and China.The Nordic region has the highest incidence of osteoporosis, a disease that makes bone prone to fra
The guidelines governing the treatment of sudden cardiac arrest exhibit variation across different nations, with treatment strategies often resting on a limited evidential foundation. A randomized international study is underway poised to address some of the most pivotal questions. Encompassing a cohort of 3,500 patients, this study aims to scrutinize the impact of different fever treatments, cont
https://www.medicine.lu.se/article/best-treatment-cardiac-arrest-new-international-study-will-provide-answer - 2025-10-03
A treatment that has reduced plaque development in animals has now been tested in people with psoriasis. Jan Nilsson at Lund University is one of the researchers behind the clinical study that showed a reduced inflammation of the coronary arteries, which in turn may reduce the risk of dying from a heart attack. People with diabetes may also benefit from the treatment in the future. Short facts abo
https://www.medicine.lu.se/article/new-treatment-atherosclerosis-may-reduce-risk-heart-attack - 2025-10-03
Higher dose cohort initiated after positive early safety evaluation in Parkinson's therapy. After a positive initial safety evaluation, the pioneering STEM-PD clinical trial has advanced to higher dose testing. STEM-PD is a first-in-human clinical trial testing a new investigational therapy for Parkinson’s disease aimed at replacing the dopamine cells lost to the disease with healthy ones derived
https://www.medicine.lu.se/article/update-on-stem-pd-clinical-trial-stem-cell-based-transplant-parkinsons-disease - 2025-10-03
By analysing small microvesicles that cells release to communicate with their surroundings in the blood, researchers at Lund University map what happens in the brains of stroke patients. The study published in the scientific journal Stroke expands our understanding of stroke and opens doors to new treatment strategies. Ischemic stroke, caused by a blood clot in the brain, is the leading cause of
https://www.medicine.lu.se/article/cell-specific-biomarkers-blood-reflect-what-happens-brain-during-stroke - 2025-10-03
There is a constant war between bacteria and their viruses, bacteriophages, where both try to outsmart each other. An international study led by Lund University provided an important missing bit to the puzzle of how the bacteria defend themselves against phages. This is an important stepping stone towards developing effective phage-based therapies to be used as an alternative to antibiotics. Bacte
https://www.medicine.lu.se/article/war-between-bacteria-and-their-virus - 2025-10-03
The EAT-Lancet diet is a framework designed to promote environmental sustainability while also preventing common diseases such as type 2 diabetes. How do we know if the diet actually works? An international research team studied seven dietary scores and found that two of them were particularly good at evaluating adherence to the diet. Reliable diet scores are important when developing sustainable
https://www.medicine.lu.se/article/research-paves-way-sustainable-dietary-guidelines - 2025-10-03
Interest in type 1 diabetes screening is growing as methods improve and new treatments become available to more patients. New research at Lund University demonstrates how screening for autoimmune diseases can be carried out on a large-scale basis. A new treatment that can delay the onset of type 1 diabetes has been approved for use in the United States. If the treatment Teplizumab becomes availabl
https://www.medicine.lu.se/article/new-method-allows-large-scale-screening-autoimmune-diseases - 2025-10-03
Antibodies are the body's superheroes, recognizing and eliminating disease-causing substances. By combining parts from antibodies, researchers at Lund University have designed a hybrid antibody that better stimulates the immune system against both the SARS-CoV-2 virus and streptococcal bacteria. Antibodies can be likened to keys, with antigens as the corresponding locks. Each antibody is uniquely
https://www.medicine.lu.se/article/recipe-great-antibody - 2025-10-03
Heart attack and stroke are common complications of diabetes, as the body's ability to repair and form vessels is impaired. Researchers at Lund University have developed a new substance with the capacity to stimulate vascular repair response and the formation of vessels. In diabetes, the body's ability to repair vascular damage caused by the disease is impaired, which can lead to complications suc
https://www.medicine.lu.se/article/new-peptide-may-reduce-risk-diabetes-complications - 2025-10-03
Filipe Pereira and his research team have discovered a recipe on how to reprogram cancer cells into antigen-presenting dendritic cells, essential for initiating and enhancing anti-tumour immunity. This approach provides a promising strategy for cancer treatment. The goal of the now awarded project is to engineer the "vehicle" to deliver the instruction converting the cells, utilizing RNA vectors f
https://www.medicine.lu.se/article/professor-filipe-pereira-awarded-erc-proof-concept-grant - 2025-10-03
Precision medicine seeks to reduce errors and improve accuracy in medical and health recommendations, but better evidence is needed to fulfil its potential. An international consortium led by Paul Franks at Lund University presents new guidelines that may increase the clinical relevance of precision medicine research. An international consensus report on precision medicine that was published in Na
https://www.medicine.lu.se/article/new-guidelines-aim-increase-accuracy-precision-medicine-research - 2025-10-03
By injecting a solution of nanoparticles around the heart, a temporary heart stimulator self-assembles, which can correct heart arrhythmia in emergency situations with the help of an external power source. After treatment, the electrode spontaneously disappears from the body. The study was conducted on animals. Short facts about the study: arrhythmia // basic research // experimental study // anim
https://www.medicine.lu.se/article/injectable-heart-stimulator-emergency-situations - 2025-10-03
In an infection, there are tens of thousands of peptides that provide a wealth of information about which bacteria have caused the infection and how severe it is. A research team at Lund University has now combined clinical questions with mathematical methods to systematically analyze these peptides. This scientific breakthrough has the potential to transform the diagnosis and treatment of infecti
https://www.medicine.lu.se/article/faster-detection-dangerous-infections - 2025-10-03
There were no differences in quality of life, symptoms, hospital admissions or mortality between a group of patients with pulmonary disease and low oxygen levels in the blood that received oxygen therapy at home for 24 hours a day, and a group that received the same therapy for 15 hours a day, according to a study from Lund University in Sweden. “This has considerable significance for patients wit
https://www.medicine.lu.se/article/no-benefits-24-hour-compared-15-hour-oxygen-therapy - 2025-10-03
Researchers at Lund University are developing a new type of gene therapy that reprograms cancer cells within tumors into immune cells that can help the immune system fight cancer. Their approach, now published in the journal Science, could lead to more effective treatments for hard-to-treat cancers. Reprogramming Cancer Cells into Immune Cells Earlier research by the team showed that three special
https://www.medicine.lu.se/article/researchers-reprogram-tumor-cells-cancer-fighting-immune-cells-living-beings - 2025-10-03
By describing his research as a battle between good and evil and likening himself to a hacker who attacks cancer cells to make them kind, PhD student Luís Oliveira took home the win in this year's Research Grand Prix. It is a competition in presentation technique for researchers, and it was held in front of an audience of almost 400 students at Helsingborg's Stadsteater on 1 October. In November,
https://www.medicine.lu.se/article/he-won-regional-heat-researcher-grand-prix-now-heading-national-contest-stockholm - 2025-10-03
For the first time, researchers have linked specific frequent defects in sperm to risk of pregnancy complications and negative impacts on the health of the baby. The study from Lund University in Sweden shows that high proportion of father’s spermatozoa possessing DNA strand breaks is associated with doubled risk of preeclampsia in women who have become pregnant by IVF. It also increases the risk
https://www.medicine.lu.se/article/defective-sperm-doubles-risk-preeclampsia - 2025-10-03
It has previously been difficult to identify DNA mutations in sperm, as these changes are rare, and most sequencing techniques have a large margin of error. Now a research study led from Lund University, have conducted a pilot study in which they examined sperm DNA and it’s similarity to mutations in children, using the advanced technique called duplex sequencing. Nearly 80 percent of all new muta
https://www.medicine.lu.se/article/new-method-enables-identification-mutations-sperm - 2025-10-03
A career in science was not on the map for Kári Stefánsson, who aspired to become a writer. But life took another road and the return to Iceland almost three decades ago marked the start of a journey that would revolutionize genetics. Meet this year’s receiver of the Eric K. Fernström Award. "Genetics is the only way to systematically study human nature. So we came to the conclusion that the way t
https://www.medicine.lu.se/article/success-makes-it-difficult-quit - 2025-10-03
