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Johan Jakobsson and his team tries to understand how the human brain is so different in complexity and size to the brains of other great apes, even though our coding genome is almost identical. In an attempt to answer that, they used induced pluripotent stem cells (iPSCs) to generate neural progenitors from both humans and chimpanzees, which is our closest living relative in evolutionary terms. Th

https://www.stemcellcenter.lu.se/article/what-makes-human-brain-different-brain-chimpanzee - 2025-12-13

Associate senior lecturer Paul Bourgine and his team has generated a “cell-based but cell-free” biomaterial harboring the necessary signals for complete bone regeneration The field of tissue engineering for replacement therapies faces multiple challenges, including reproducible performance and scalability towards industrial production. Paul Bourgine and his research group at the SCC have come up w

https://www.stemcellcenter.lu.se/article/towards-establishment-human-tissue-factory-programming-cells-building-units - 2025-12-13

At 2pm on the 28th of October scientists all over Sweden were scrolling though the list of awarded grants in Medicine and health from The Swedish Research Council, in hope to find their name. The yearly awarded grants from The Swedish Research Council continues to support high quality research with their Project grants as well as enabling promising young scientists to establish themselves as group

https://www.stemcellcenter.lu.se/article/scc-scientists-awarded-326-million-swedish-research-council - 2025-12-13

The Soneji lab has developed an open-source virtual reality environment enabling scientists to analyse their single-cell sequencing data in 3D. Current single cell sequencing technology enable researchers to measure transcriptome-wide gene expression within thousands of individual cells in a single experiment. These type of projects generates enormous amounts of data which needs to be made compreh

https://www.stemcellcenter.lu.se/article/single-cell-analysis-enters-third-dimension - 2025-12-13

The Foundation supports research aiming to elucidate the mechanisms behind Parkinson’s disease with the vision of improved treatments as well as prevention of the disease. This year's annual announcement of granted project proposals from The Swedish Parkinson Foundation revealed a total support of 7 million SEK, from which over a million SEK went to stem cell-based projects at the SCC. We wish to

https://www.stemcellcenter.lu.se/article/swedish-parkinson-foundation-grants-several-scc-projects - 2025-12-13

Maria performed her doctoral studies in the group of Jenny Hansson at the SCC and defended her thesis on June 9th, 2021. Maria’s doctoral studies at the SCC resulted in the thesis “Molecular and Functional Dynamics of Hematopoietic Progenitor Cell Fate During Ontogeny” in which she focused her work on blood development and how it affects our immune system. The assessment committee at The Swedish S

https://www.stemcellcenter.lu.se/article/swedish-society-hematology-has-awarded-maria-jassinskaja-thesis-year - 2025-12-13

Taha Sen’s PhD thesis focus on the life span of red blood cells and elucidates the important role of mitochondria. He is defending his thesis on the 17th of November and in this interview he gives us an overview of his results as well as what it’s been like being a doctoral student during a pandemic. Can you tell us about the research during your PhD? I’ve been focusing my thesis work on the life

https://www.stemcellcenter.lu.se/article/phd-defence-interview-taha-sen - 2025-12-13

Martin Stenlo’s PhD thesis aims to improve the intensive care of lung patients as well as to increase the health status of transplantable donor lungs which will improve the success rate of lung transplantation. He is defending his thesis on the 12th of November and in this interview he tells us about his translational research and his time as a PhD student. It can’t be an easy task to combine a fu

https://www.stemcellcenter.lu.se/article/phd-defence-interview-martin-stenlo - 2025-12-13

The Swedish Cancer Foundation supports cancer research with a record sum this year: 850 million SEK divided between 230 research projects, selected based the highest chance of achieving successful results and contribute to defeating cancer. We are very happy to announce that 7 of those projects belong to scientists of Lund Stem Cell Center. The Swedish Cancer Foundation is one of Sweden's largest

https://www.stemcellcenter.lu.se/article/swedish-cancer-foundation-funds-lund-scc-scientists-232-million-sek - 2025-12-13

Martiné Wlosinska, medical doctor and PhD student, will be defending her thesis titled “Preventing Cardiovascular Disease. Complementary precision medicine” on the 26th of November. In this interview, Martiné tells us about the effect of aged garlic extract on progression of cardiovascular disease and the importance of treating patients on a personalized level. Can you tell us more about your PhD

https://www.stemcellcenter.lu.se/article/phd-defence-interview-martine-wlosinska - 2025-12-13

Giulia Beneventi has investigated the role of RNA modifications and post-transcriptional control in cancer and stem cells. In this interview, she tells us about her research and what is it like to be a PhD student in newly established group. Giulia defends her thesis on the 8th of December.   What have you been working with during your PhD studies? The main aim of my PhD project was to unravel pos

https://www.stemcellcenter.lu.se/article/phd-defence-interview-giulia-beneventi - 2025-12-13

The Distinguished Professor programme was created by the Swedish Research Council to allow the most prominent researchers to conduct long-term, ground-breaking research which has great potential for achieving scientific breakthroughs. The Distinguished Professor programme is awarded to at least 2 scientists every second year between 2019-2029 by the Swedish Research Council. It was created to allo

https://www.stemcellcenter.lu.se/article/malin-parmar-awarded-distinguished-professorship-swedish-research-council - 2025-12-13

The career program Wallenberg Academy Fellows is the largest private investment in young researchers in Sweden. It provides the most promising young researchers with long-term resources, giving them excellent opportunities to establish themselves and build up their research groups. Wallenberg Academy Fellows is designed for young researchers and was launched by the Knut and Alice Wallenberg Founda

https://www.stemcellcenter.lu.se/article/daniella-rylander-ottosson-has-been-admitted-wallenberg-academy-fellow - 2025-12-13

Mikael has been investigating the influence of cellular heterogeneity in ontogeny, ageing and leukemia. In this interview, he tells us about his time as a PhD student in the group of Stem Cells and Leukemia at Lund Stem Cell Center. He defends his thesis on the 16th of December. What have you been working with during your PhD studies? My PhD project was aimed at resolving cellular heterogeneity wi

https://www.stemcellcenter.lu.se/article/phd-defence-interview-mikael-sommarin-0 - 2025-12-13

In their latest study, published in Nature Communications, the Parmar Lab has established midbrain organoids using silk microfibers as scaffolds, offering a refined in vitro model of human midbrain development. They have studied their silk midbrain organoids using single cell sequencing, proteomics and functional assessment in order to shed light on the developmental trajectory, maturation and sub

https://www.stemcellcenter.lu.se/article/human-midbrain-organoids-grown-silk-recapitulate-midbrain-development-and-support-functionally - 2025-12-13

In a recent study from the SCC group of Niels-Bjarne Woods and collaborators, they have investigated the metabolic changes accompanying the emergence of blood during embryonic development. They discovered a previously unknown metabolic switch during endothelial to hematopoietic transition (EHT), the process by which the first blood cells are formed. This switch showed to be crucial in the determin

https://www.stemcellcenter.lu.se/article/metabolic-switch-during-embryonic-hematopoiesis-major-regulator-lineage-commitment - 2025-12-13

Ludwig Schmiderer has studied how to overcome delivery challenges in stem cell biology with nanotechnology. In this interview, he tells us about his research and generative art. What have you been working with during your PhD studies? At the beginning of my PhD, I was trying to reengineer the CRISPR/Cas9 system to make it work in mitochondria instead of nucleus. The project started off quite well

https://www.stemcellcenter.lu.se/article/phd-defence-interview-ludwig-schmiderer - 2025-12-13

Stem cell transplantation is a cornerstone in the treatment of blood malignancies. In order to succeed, stem cells need to be harvested from a donor. This requires that hematopoietic stem and progenitor cells (HSPC) are mobilized from the donor’s bone marrow into the blood. In a new study, the Nilsson lab discovered DNA sequence variants that regulate HSPC levels in human blood, exposing potential

https://www.stemcellcenter.lu.se/article/large-scale-genome-wide-association-study-reveals-new-potential-drug-target-blood-stem-cell - 2025-12-13

The Pereira research group has previously shown that it is possible to reprogram human skin cells into dendritic cells that strengthen the immune system. However, the efficiency of these reprogrammed cells has been shown to be very low. New studies now indicate that there are ways to increase the efficiency of these reprogrammed cells by over 75%. These findings provide mechanistic insights into h

https://www.stemcellcenter.lu.se/article/new-findings-indicate-ways-increase-efficiency-reprogrammed-immune-cells - 2025-12-13

Anna Fossum, Project Manager at the StemTherapy FACS Core Facility research infrastructure, has been sorting cells with a variety of types of FACS machines for the past 23 years. But she hasn’t gotten tired yet of the job – quite the opposite. And now she has a new and more powerful member of the “FACS family” to look after. “I really love my job! It’s stimulating to meet so many people and hear a

https://www.stemcellcenter.lu.se/article/new-addition-lund-stem-cell-center-facs-facility - 2025-12-13