Sökresultat

In this comparative effectiveness study, a total of 141 randomized clinical trials referenced in the National Comprehensive Cancer Network Clinical Practice Guidelines for 8 common solid tumor types were identified. Data on participants within the National Cancer Database (NCDB) diagnosed between 2004 and 2014, matching the eligibility criteria of the randomized clinical trial, were obtained. The

https://www.lupop.lu.se/article/evaluation-use-cancer-registry-data-comparative-effectiveness-research - 2025-12-01

In the developing countries with high mortality rates, poisoning is considered to be one of the most common causes of admission to emergency wards. Given the importance of registering data on poisoned patients, it is very important to have a complete poisoning Minimum Data Set (MDS). Therefore, the purpose of this study was to determine an MDS for poisoning registry in Iran. Read more at https://o

https://www.lupop.lu.se/article/development-national-minimum-data-set-poisoning-registry-iran - 2025-12-01

The goal of the global congestive heart failure (G-CHF) registry is to collect comparative international data on heart failure characteristics, management, and outcomes and to better understand the determinants that impact the clinical course of heart failure. Read more at https://www.sciencedirect.com/science/article/abs/pii/S0002870320301800

https://www.lupop.lu.se/article/multinational-registry-study-characteristics-and-outcomes-heart-failure-patients-global-congestive - 2025-12-01

Cerebral palsy (CP) describes a heterogeneous group of motor disorders resulting from disturbance in the developing brain. CP occurs in approximately 2.1 per 1000 live births in high-income countries, but in low- and middle-income countries (LMICs) the prevalence and severity of CP may be greater and aetiological risk factors different. In Sri Lanka, a LMIC, there have been no epidemiological stud

https://www.lupop.lu.se/article/protocol-sri-lankan-cerebral-palsy-register-pilot-study - 2025-12-01

Patients with advanced cancer commonly suffer from both distressing symptoms and cognitive impairment, but the effect of cognitive impairment on the reliability and validity of symptom self-report is unknown. Read more at https://www.sciencedirect.com/science/article/pii/S0885392420301342

https://www.lupop.lu.se/article/mild-moderate-cognitive-impairment-does-not-affect-ability-self-report-important-symptoms-patients - 2025-12-01

The ability to provide primary care with the help of a digital platform raises both opportunities and risks. While access to primary care improves, overuse of services and medication may occur. The use of digital care technologies is likely to continue to increase and evidence of its effects, costs and distributional impacts is needed to support policy-making. Read more at https://bmjopen.bmj.com/

https://www.lupop.lu.se/article/study-protocol-effects-costs-and-distributional-impact-digital-primary-care-infectious-diseases - 2025-12-01

Recent research showed that exposure to the vaccine against polio in early life had no long-term economic benefits among native Swedes. However, whether this result holds for individuals from other countries remains unexplored. This study explores the relationship between exposure to the vaccine and later-life outcomes, but focuses on individuals who migrated to Sweden (birth cohorts 1946–1971), a

https://www.lupop.lu.se/article/were-there-long-term-economic-effects-exposure-polio-vaccination-analysis-migrants-sweden-1946-2003 - 2025-12-01

Alterations in the human metabolome occur years before clinical manifestation of type 2 diabetes (T2DM). By contrast, there is little knowledge of how metabolite alterations in individuals with diabetes relate to risk of diabetes complications and premature mortality. Metabolite profiling was performed using liquid chromatography-mass spectrometry in 743 participants with T2DM from the population-

https://www.lupop.lu.se/article/plasma-metabolites-associate-all-cause-mortality-individuals-type-2-diabetes - 2025-12-01

Dementia disorders predispose for lethal complications and decrease life expectancy. A more profound knowledge regarding end‐stage conditions in dementia could therefore ameliorate treatment and care of these patients. Read more at https://onlinelibrary.wiley.com/doi/full/10.1111/ene.14450

https://www.lupop.lu.se/article/cause-death-autopsy-confirmed-dementia-disorders - 2025-12-01

The Danish National Patient Registry (DNPR) has been the source of several epidemiological studies of inflammatory bowel disease (IBD). However, the validation dates back to 1996 and lacks outpatient records and disease classification. The aim of this study was to update the validation and assess the validity and reliability of using the registry in disease classification. Read more at https://www

https://www.lupop.lu.se/article/validation-ulcerative-colitis-and-crohns-disease-and-their-phenotypes-danish-national-patient - 2025-12-01

The aim was to investigate associations between the experience of parental separation/divorce in childhood and tobacco smoking in adulthood, adjusting for economic stress in childhood and adulthood and psychological health (General Health Questionnaire GHQ12). Methods: The 2012 public-health survey in Skåne, southern Sweden, is a cross-sectional postal questionnaire population-based study with 28,

https://www.lupop.lu.se/article/parental-separationdivorce-childhood-and-tobacco-smoking-adulthood-population-based-study - 2025-12-01

To compare consultations carried out via video with those performed in person for patients with painful, hard-to-heal ulcers, with a focus on ulcer pain and pain treatment. A further aim was to investigate predictors for pain and pain treatment. Read more at https://www.magonlinelibrary.com/doi/full/10.12968/jowc.2020.29.Sup8.S18

https://www.lupop.lu.se/article/pain-and-analgaesics-patients-hard-heal-ulcers-using-telemedicine-or-standard-consultations - 2025-12-01

Statins, commonly used to treat hypercholesterolemia, have also been proposed as anti-cancer agents. The identification of a predictive marker is essential. The 3-hydroxy-3-methylglutaryl-coenzyme-A reductase (HMGCR), which is inhibited by statins, might serve as such a marker. Thorough antibody validation was performed for four different HMGCR antibodies. Tumor expression of HMGCR (#AMAb90619, CL

https://www.lupop.lu.se/article/statin-use-hmgcr-expression-and-breast-cancer-survival-malmo-diet-and-cancer-study - 2025-12-01

With the increased number of cancer survivors, it is necessary to explore the effect of cancer and its treatments on pregnancy outcomes, such as preterm birth, which seriously endangers the health of offspring. We aimed to explore the risk of being born preterm among offspring of cancer survivors. Read more at https://www.frontiersin.org/articles/10.3389/fonc.2020.01352/full

https://www.lupop.lu.se/article/risk-being-born-preterm-offspring-cancer-survivors-national-cohort-study - 2025-12-01

The Swedish National Quality Registries (NQRs) contain individual-level health care data for specific patient populations, or patients receiving specific interventions. Approximately 90% of the 105 Swedish NQRs include any patient-reported outcome measure, with EQ-5D being the most common. As there has been no general overview of EQ-5D data within the NQRs, this study fills a knowledge gap by repo

https://www.lupop.lu.se/article/collection-and-use-eq-5d-follow-decision-making-and-quality-improvement-health-care-case-swedish - 2025-12-01

To determine development of new and worsening meniscal damage over 5 years after acute anterior cruciate ligament (ACL) injury comparing rehabilitation plus early ACL reconstruction (’earlyACLR’) versus rehabilitation with optional delayed ACL reconstruction (’optional-delayed-ACLR’). Read more at https://bjsm.bmj.com/content/bjsports/early/2019/10/25/bjsports-2019-101125.full.pdf

https://www.lupop.lu.se/article/does-early-anterior-cruciate-ligament-reconstruction-prevent-development-meniscal-damage-results - 2025-12-01

Housing adaptation aims to enable clients to live independently in their own homes. Studies focusing on participation in everyday life following a housing adaptation are lacking and needed. This study aimed to explore housing adaptation clients' experiences of participation in everyday life before and after a housing adaptation, through the lens of a housing adaptation, using a qualitative follow-

https://www.lupop.lu.se/article/participation-everyday-life-and-after-housing-adaptation - 2025-12-01

This study explored factors associated with interest in taking PrEP among men who have sex with men (MSM) attending HIV testing venues in Sweden. Data from 658 HIV-negative respondents, surveyed by a questionnaire at six sites, were analyzed descriptively and by univariable and multivariable logistic regression. Read more at https://link.springer.com/article/10.1007/s10508-020-01740-9

https://www.lupop.lu.se/article/interest-taking-hiv-pre-exposure-prophylaxis-associated-behavioral-risk-indicators-and-self - 2025-12-01

Health impact assessments of differential air pollution rely on epidemiologically established relationships between concentration levels where people are exposed and adverse health outcomes. To assess air pollution concentrations, land use regression is commonly used. However, an alternative tool is dispersion modelling, where a detailed inventory of pollution sources together with meteorological

https://www.lupop.lu.se/article/particle-concentrations-dispersion-modelling-and-evaluation-southern-sweden - 2025-12-01

While the relationship between hypertension and incident intracerebral haemorrhage is well established, other risk factors are less clear. This study examined risk factors for primary intracerebral haemorrhage, separately for lobar and non-lobar intracerebral haemorrhage. Read more at https://journals.sagepub.com/doi/full/10.1177/2396987320932069

https://www.lupop.lu.se/article/risk-factors-intracerebral-haemorrhage-results-prospective-population-based-study - 2025-12-01